Research Papers

Improved surface-enhanced Raman scattering of insulin fibril templated colloidal gold nanoparticles on silicon

[+] Author Affiliations
Chiung-Wen Hsieh, Pei-Ying Lin, Shuchen Hsieh

National Sun Yat-sen University, Department of Chemistry, 70 Lien-Hai Road, Kaohsiung, 80424, Taiwan

J. Nanophoton. 6(1), 063501 (Mar 12, 2012). doi:10.1117/1.JNP.6.063501
History: Received October 14, 2011; Revised November 22, 2011; Accepted November 30, 2011
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Abstract.  Insulin fibrils were used as a biotemplate to attach gold nanoparticles to silicon wafer surfaces for application as surface-enhanced Raman scattering (SERS) substrates. Gold nanoparticles (NP) attach to the insulin fibrils through electrostatic interactions forming chains of discreet NPs. A combination of 4-aminothiophenol and 4-Mercaptobenzoic acid were used as probe molecules to evaluate the Raman signal enhancement that was 104 to 106. The SERS signal was strongly enhanced on these surfaces due to the close inter-particle spacing of the patterned gold NPs.

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© 2012 Society of Photo-Optical Instrumentation Engineers

Citation

Chiung-Wen Hsieh ; Pei-Ying Lin and Shuchen Hsieh
"Improved surface-enhanced Raman scattering of insulin fibril templated colloidal gold nanoparticles on silicon", J. Nanophoton. 6(1), 063501 (Mar 12, 2012). ; http://dx.doi.org/10.1117/1.JNP.6.063501


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