Research Papers

Plasmonic phototherapy using gold nanospheres and gold nanorods irradiated with light-emitting diodes

[+] Author Affiliations
Gananathan Poorani, Aruna Prakasa Rao, Ganesan Singaravelu

Anna University, Department of Medical Physics, Sardar Patel Road, Guindy, Chennai 600 025, India

Elanchezhiyan Manickam

University of Madras, IBMS, Department of Medical Microbiology, Taramani, Chennai 600113, India

J. Nanophoton. 10(2), 026027 (Jun 15, 2016). doi:10.1117/1.JNP.10.026027
History: Received March 3, 2016; Accepted May 24, 2016
Text Size: A A A

Abstract.  Gold nanoparticles (GNPs) provide different modes of therapeutic responses in cells depending on their size and shape. We have studied two modifications of GNPs exhibiting surface plasmon resonances (SPRs) with phototherapeutic effects in nonmalignant Vero and malignant HeLa cell lines. The cells were treated with 30-nm-size gold nanospheres (GNSs) (having SPR at a wavelength of 530 nm) and with gold nanorods (GNRs) (having SPR at 630 nm). The plasmonic phototherapy effect in cells was provided by irradiating them with green and red light-emitting diodes (LEDs). The cytotoxicities of GNPs were determined by MTT assay. Both the GNSs and GNRs were found to be biocompatible and have efficient phototherapeutic activity with LEDs.

Figures in this Article
© 2016 Society of Photo-Optical Instrumentation Engineers

Citation

Gananathan Poorani ; Aruna Prakasa Rao ; Ganesan Singaravelu and Elanchezhiyan Manickam
"Plasmonic phototherapy using gold nanospheres and gold nanorods irradiated with light-emitting diodes", J. Nanophoton. 10(2), 026027 (Jun 15, 2016). ; http://dx.doi.org/10.1117/1.JNP.10.026027


Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Related Book Chapters

Topic Collections

Advertisement
  • Don't have an account?
  • Subscribe to the SPIE Digital Library
  • Create a FREE account to sign up for Digital Library content alerts and gain access to institutional subscriptions remotely.
Access This Article
Sign in or Create a personal account to Buy this article ($20 for members, $25 for non-members).
Access This Proceeding
Sign in or Create a personal account to Buy this article ($15 for members, $18 for non-members).
Access This Chapter

Access to SPIE eBooks is limited to subscribing institutions and is not available as part of a personal subscription. Print or electronic versions of individual SPIE books may be purchased via SPIE.org.