Both in vitro and in vivo acoustic measurements show feasibility for detecting tumors using MNPs. Moreover, magnetoacoustical detection and localization is a base for work, which is done in the lab regarding approximation of the temperature at the tumor location by using a combination of localization and thermal imaging. However, there are several ways to improve the acoustic measurements enabling the detection of smaller tumors, in greater depths and with higher signal-to-noise ratio (SNR). First, the stimulation magnetic signal should be narrower in the frequency domain. By narrowing its frequency band, the measured acoustic signal is expected to behave accordingly, which will result in higher SNR of the acquired signal. Moreover, if stimulation is narrower in the frequency domain, frequency sweeping would take less time, and will enable better averaging of recorded data. It should be noted that other temporal shapes of magnetic field can be successfully used for the generation of the acoustic signal from MNPs, and may be implemented in a future work based on the presented method.35,36 Second, a more suitable transducer can be used for acquiring the acoustic signal as the transducer used in this experiment was a hydrophone that is most suitable for underwater measurement. In the in vivo measurements, the contact area between the transducer and the mouse skin was rather small. Therefore, future improvement should consider the use of other transducers more suitable for in vivo measurements. Third, a future improvement might include the use of an array of transducers. Using such an array may enable not only the presence of a tumor but also could provide information regarding its morphology.