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5 March 2021 Ultra-low concentration SERS Detection of biomolecules using rainbow trapping in width-graded plasmonic gratings
Moein Shayegannia, Katelyn Dixon, Naomi Matsuura, Nazir P. Kherani
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Proceedings Volume 11661, Plasmonics in Biology and Medicine XVIII; 1166107 (2021) https://doi.org/10.1117/12.2583176
Event: SPIE BiOS, 2021, Online Only
Abstract
This study shows unique capability of deep-subwavelength metal-insulator-metal (MIM) width-graded nano-gratings in offering high intensity electromagnetic field. The plasmonic field is underpinned by the strong coupling of the surface plasmon polaritons on the sidewalls of the nanogrooves. We present quantitative SERS detection of various biomolecule species at an ultra-low concentration corresponding to detection of single molecule. We report limit of detection of a gold coated bullseye width-graded plasmonic nano-grating as a SERS platform in detecting small molecule (such as propylene glycol) or sepsis biomarkers (such as protein c) at multiple wavelengths of light.
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Moein Shayegannia, Katelyn Dixon, Naomi Matsuura, and Nazir P. Kherani "Ultra-low concentration SERS Detection of biomolecules using rainbow trapping in width-graded plasmonic gratings", Proc. SPIE 11661, Plasmonics in Biology and Medicine XVIII, 1166107 (5 March 2021); https://doi.org/10.1117/12.2583176
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KEYWORDS
Surface enhanced Raman spectroscopy
Molecules
Plasmonics
Gold
Molecular nanotechnology
Nanotechnology
Plasmons
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