Optimal sizes of gold nanoparticles for laser treatment of tumors

Alexey P. Popov; Alexander V. Priezzhev; Risto Myllylä

doi:10.1117/12.741501

1 May 2007 Optimal sizes of gold nanoparticles for laser treatment of tumors

Alexey P. Popov, Alexander V. Priezzhev, Risto Myllylä

Proceedings Volume 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine; 65343K (2007) https://doi.org/10.1117/12.741501
Event: Fifth International Conference on Photonics and Imaging in Biology and Medicine, 2006, Wuhan, China

Abstract

In the present paper, the problem of laser treatment of tumors by means of gold nanoparticles is discussed. One of the mechanisms of cancerous cells destruction is formation of small bubbles on cell membranes and inside cells around gold nanoparticles induced by laser pulse absorption by the particles. It is shown by Mie theory calculations that the optimal spectral region for such tumor treatment is within 400 - 550 nm with the corresponding nanoparticles sizes to be 30 - 40 nm. The appropriate durations of laser pulses for such kind of laser therapy are under 1 ns in this spectral region.

Citation Download Citation

Alexey P. Popov, Alexander V. Priezzhev, and Risto Myllylä "Optimal sizes of gold nanoparticles for laser treatment of tumors", Proc. SPIE 6534, Fifth International Conference on Photonics and Imaging in Biology and Medicine, 65343K (1 May 2007); https://doi.org/10.1117/12.741501

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available