Surface-enhanced Raman spectroscopy of mouse serum using silver colloid substrate

Shupeng Liu; Hongfei Zhu; Shaofeng Chen; Zhenyi Chen; Na Chen; Tingyun Wang

doi:10.1117/12.915979

30 January 2012 Surface-enhanced Raman spectroscopy of mouse serum using silver colloid substrate

Shupeng Liu, Hongfei Zhu, Shaofeng Chen, Zhenyi Chen, Na Chen, Tingyun Wang

Proceedings Volume 8351, Third Asia Pacific Optical Sensors Conference; 83512I (2012) https://doi.org/10.1117/12.915979
Event: Asia Pacific Optical Sensors Conference, 2012, Sydney, Australia

Abstract

In this paper, the Raman spectra of the cancer nude mouse serum were measured using surface-enhanced Raman scattering (SERS) with the silver colloid substrate. The result indicated that the SERS spectra of the serum increased several peaks compared with conventional Raman spectra. More ever, these peaks were so crucial for analysis of the serum component and structure so that the information of the protein, carbohydrate, lipid and other trace amounts component could be analyzed through SERS spectra. Therefore, SERS technique is reliably used to compare relative intensity shifts and to investigate the adsorption of biological molecular proteins on Ag nanoparticles.

Citation Download Citation

Shupeng Liu, Hongfei Zhu, Shaofeng Chen, Zhenyi Chen, Na Chen, and Tingyun Wang "Surface-enhanced Raman spectroscopy of mouse serum using silver colloid substrate", Proc. SPIE 8351, Third Asia Pacific Optical Sensors Conference, 83512I (30 January 2012); https://doi.org/10.1117/12.915979

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KEYWORDS

Raman spectroscopy

Silver

Surface enhanced Raman spectroscopy

Proteins

Raman scattering

Cancer

Molecules

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