Confocal microscopy to guide laser ablation of basal cell carinoma: a preliminary feasibility study

Bjorg A. Larson; Heidy Sierra; Jason Chen; Milind Rajadhyaksha

doi:10.1117/12.2005482

8 March 2013 Confocal microscopy to guide laser ablation of basal cell carinoma: a preliminary feasibility study

Bjorg A. Larson, Heidy Sierra, Jason Chen, Milind Rajadhyaksha

Proceedings Volume 8565, Photonic Therapeutics and Diagnostics IX; 856502 (2013) https://doi.org/10.1117/12.2005482
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Laser ablation may be a promising method for removal of skin lesions, with the potential for better cosmetic outcomes and reduced scarring and infection. An obstacle to implementing laser ablation is that the treatment leaves no tissue for histopathological analysis. Pre-operative and intra-operative mapping of BCCs using confocal microscopy may guide the ablation of the tumor until all tumor is removed. We demonstrate preliminary feasibility of confocal microscopy to guide laser ablation of BCCs in freshly excised tissue from Mohs surgery. A 2940 nm Er:YAG laser provides efficient ablation of tumor with reduced thermal damage to the surrounding tissue.

Citation Download Citation

Bjorg A. Larson, Heidy Sierra, Jason Chen, and Milind Rajadhyaksha "Confocal microscopy to guide laser ablation of basal cell carinoma: a preliminary feasibility study", Proc. SPIE 8565, Photonic Therapeutics and Diagnostics IX, 856502 (8 March 2013); https://doi.org/10.1117/12.2005482

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