Poster
13 March 2024 Optimizing procedures for hybrid infrared fluorescence-optoacoustic functional neuroimaging
Sarah Shaykevich, Daniel Razansky, Shy Shoham
Author Affiliations +
Conference Poster
Abstract
Optoacoustic tomography (OAT) holds promise for enhancing neuroimaging in the mouse brain. It provides the opportunity for multispectral, mesoscopic, high temporal resolution imaging of neural activity using exogenous and endogenous contrasts. OAT data also presents challenges, such as the need to optimize reconstruction and spectral unmixing parameters as well as the need to overcome light attenuation and nonuniformity. We demonstrate methods to optimize OAT acquisition and analysis for functional neuroimaging, including using a hybrid fluorescence-OAT approach.
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Sarah Shaykevich, Daniel Razansky, and Shy Shoham "Optimizing procedures for hybrid infrared fluorescence-optoacoustic functional neuroimaging", Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC1284230 (13 March 2024); https://doi.org/10.1117/12.3003204
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KEYWORDS
Neuroimaging

Infrared radiation

Infrared imaging

Design and modelling

Imaging systems

Optoacoustics

Spatial resolution

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