Development of novel hologram-based sensors for patient dosimetry in daylight photodynamic therapy (D-PDT)

Saoirse Maher; Jackie McCavana; Seán Cournane; Suzanne Martin; Dervil Cody

doi:10.1117/12.2689897

13 March 2024 Development of novel hologram-based sensors for patient dosimetry in daylight photodynamic therapy (D-PDT)

Saoirse Maher, Jackie McCavana, Seán Cournane, Suzanne Martin, Dervil Cody

Author Affiliations +

Proceedings Volume PC12823, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXII; PC128230A (2024) https://doi.org/10.1117/12.2689897
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Here, a holographic sensor technology capable of measuring the dose received at the patient treatment site during daylight photodynamic therapy (D-PDT) is presented. The proposed transmission-mode holographic sensor enables more precise, customized dosimetry, with the objective of quantifying the weighted PPIX dose a patient receives, facilitating the potential for further optimization of therapies. The experimental development and optimization of the photosensitive film-based holographic sensor for D-PDT dosimetry is described. Both the photosensitive film fabrication process and the two-beam interferometric recording of holographic gratings have been optimized. Preliminary findings support the suitability of holographic gratings for D-PDT dosimetry.

Conference Presentation

Citation Download Citation

Saoirse Maher, Jackie McCavana, Seán Cournane, Suzanne Martin, and Dervil Cody "Development of novel hologram-based sensors for patient dosimetry in daylight photodynamic therapy (D-PDT)", Proc. SPIE PC12823, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXXII, PC128230A (13 March 2024); https://doi.org/10.1117/12.2689897

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