Study on nasopharyngeal cancer tissue using surface-enhanced Raman spectroscopy

Xiaosong Ge; Xueliang Lin; Zhihong Xu; Guoqiang Wei; Wei Huang; Duo Lin

doi:10.1117/12.2246328

31 October 2016 Study on nasopharyngeal cancer tissue using surface-enhanced Raman spectroscopy

Xiaosong Ge, Xueliang Lin, Zhihong Xu, Guoqiang Wei, Wei Huang, Duo Lin

Proceedings Volume 10024, Optics in Health Care and Biomedical Optics VII; 1002446 (2016) https://doi.org/10.1117/12.2246328
Event: SPIE/COS Photonics Asia, 2016, Beijing, China

Abstract

Surface-enhanced Raman spectroscopy (SERS) can provide detailed molecular structure and composition information, and has demonstrated great potential in biomedical filed. This spectroscopy technology has become one of the most important optical techniques in the early diagnosis of cancer. Nasopharyngeal cancer (NPC) is a malignant neoplasm arising in the nasopharyngeal epithelial lining, which has relatively high incidence and death rate in Southeast Asia and southern China. This paper reviews the current progress of SERS in the field of cancer diagnostics, including gastric cancer, colorectal cancer, cervical cancer and nasopharyngeal cancer. In addition to above researches, we recently develop a novel NPC detection method based on tissue section using SERS, and obtain primary results. The proposed method has promising potential for the detection of nasopharyngeal carcinoma.

Citation Download Citation

Xiaosong Ge, Xueliang Lin, Zhihong Xu, Guoqiang Wei, Wei Huang, and Duo Lin "Study on nasopharyngeal cancer tissue using surface-enhanced Raman spectroscopy", Proc. SPIE 10024, Optics in Health Care and Biomedical Optics VII, 1002446 (31 October 2016); https://doi.org/10.1117/12.2246328

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