OCT-based characterization of the nonlinear properties of biological tissues in various states

Alexandr A. Sovetsky; Ekaterina V. Gubarkova; Lev A. Matveev; Alexander L. Matveyev; Marina A. Sirotkina; Natalia D. Gladkova; Vladimir Y. Zaitsev

doi:10.1117/12.2306246

17 May 2018 OCT-based characterization of the nonlinear properties of biological tissues in various states

Alexandr A. Sovetsky, Ekaterina V. Gubarkova, Lev A. Matveev, Alexander L. Matveyev, Marina A. Sirotkina, Natalia D. Gladkova, Vladimir Y. Zaitsev

Author Affiliations +

Proceedings Volume 10685, Biophotonics: Photonic Solutions for Better Health Care VI; 1068536 (2018) https://doi.org/10.1117/12.2306246
Event: SPIE Photonics Europe, 2018, Strasbourg, France

Abstract

Soft biological tissues manifest strongly pronounced nonlinear elastic behavior. Namely, the Young modulus for some tissues strongly depends on the applied stress. This property can be evaluated by compressional OCT elastography. We demonstrate the evaluation of nonlinear elastic properties on the samples of coronary arteries, breast cancer and cornea. The developed technique can be used for further investigation of the nonlinear properties of healthy and pathological tissues.

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Alexandr A. Sovetsky, Ekaterina V. Gubarkova, Lev A. Matveev, Alexander L. Matveyev, Marina A. Sirotkina, Natalia D. Gladkova, and Vladimir Y. Zaitsev "OCT-based characterization of the nonlinear properties of biological tissues in various states", Proc. SPIE 10685, Biophotonics: Photonic Solutions for Better Health Care VI, 1068536 (17 May 2018); https://doi.org/10.1117/12.2306246

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