In vivo Mirau-type optical coherence microscopy with symmetrical illumination

Tuan-Shu Ho; Ming-Rung Tsai; Chih-Wei Lu

doi:10.1117/12.2544632

21 February 2020 In vivo Mirau-type optical coherence microscopy with symmetrical illumination

Tuan-Shu Ho, Ming-Rung Tsai, Chih-Wei Lu

Proceedings Volume 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV; 112280X (2020) https://doi.org/10.1117/12.2544632
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Optical coherence microscopy (OCM) is an efficient tool to acquire cellular-resolution morphological images. In our previous study, we presented a Mirau-type OCM which provides both in vivo cross-sectional (B-scan) and en face imaging with a broadband extended source. However, two issues were encountered in B-scan mode. One is the illumination efficiency is low because the illumination area is much larger than the area of interest. The other is the image quality is degraded by linear artifacts. In this report, we use a symmetrical illumination design to improve the illumination efficiency and image quality of B-scan at the same time.

Citation Download Citation

Tuan-Shu Ho, Ming-Rung Tsai, and Chih-Wei Lu "In vivo Mirau-type optical coherence microscopy with symmetrical illumination", Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112280X (21 February 2020); https://doi.org/10.1117/12.2544632

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available