CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 11621 > Article
Presentation
5 March 2021 Photoacoustic identification of lipid patterns in advanced atherosclerotic plaques
Sophinese Iskander-Rizk, Mirjam Visscher, Astrid Moerman, Nuria Slijkhuis, Antonius F. W. van der Steen, Kim van der Heiden, Gijs van Soest
Author Affiliations +
Proceedings Volume 11621, Diagnostic and Therapeutic Applications of Light in Cardiology 2021; 116210K (2021) https://doi.org/10.1117/12.2577586
Event: SPIE BiOS, 2021, Online Only
Abstract
Atherosclerosis is a disease characterized by the narrowing of the arteries as a result of plaque buildup. Lipid-rich plaques are hypothesized to be ‘vulnerable’ plaques with higher risks of rupture. In order to identify lipid biomarkers in-vivo, we use an in-house built photoacoustic imaging microscope system in tandem with mass spectrometer imaging for lipid full characterization. We show photoacoustic lipid spectra of sectioned human carotid endarterectomy samples on histological glass slides to unravel a photoacoustic lipid spectral histology ranging from 1140 nm to 1250 nm. We relate the spectral features identified by PAM to lipids found by mass spectrometry imaging.
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Sophinese Iskander-Rizk, Mirjam Visscher, Astrid Moerman, Nuria Slijkhuis, Antonius F. W. van der Steen, Kim van der Heiden, and Gijs van Soest "Photoacoustic identification of lipid patterns in advanced atherosclerotic plaques", Proc. SPIE 11621, Diagnostic and Therapeutic Applications of Light in Cardiology 2021, 116210K (5 March 2021); https://doi.org/10.1117/12.2577586
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Photoacoustic spectroscopy
Mass spectrometry
Photoacoustic imaging
Imaging systems
In vivo imaging
Microscopes
Spectroscopy
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top