Quantitative full-field transient elastography based on digital holography

Agathe Marmin; Gabrielle Laloy-Borgna; Sybille Facca; Sylvain Gioux; Stefan Catheline; Amir Nahas

doi:10.1117/12.2578581

5 March 2021 Quantitative full-field transient elastography based on digital holography

Agathe Marmin, Gabrielle Laloy-Borgna, Sybille Facca, Sylvain Gioux, Stefan Catheline, Amir Nahas

Proceedings Volume 11645, Optical Elastography and Tissue Biomechanics VIII; 116450A (2021) https://doi.org/10.1117/12.2578581
Event: SPIE BiOS, 2021, Online Only

Abstract

Shear-wave elastography is based on the imaging of displacements induced by the propagation of shear-waves through a medium. A full-field off-axis digital holography setup is utilized here to image surface displacements with high sensitivity. A low frame-rate camera is combined with a stroboscopic approach to achieve propagation imaging. We present the latest results using time of flight and time-reversal-based methods to map stiffness from a propagation movie. The methods are tested on simulation images obtained using a finite difference algorithm. Experimental images with the optical setup on agarose test samples mimicking biological tissues and first results on an ex-vivo biological sample are presented.

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Citation Download Citation

Agathe Marmin, Gabrielle Laloy-Borgna, Sybille Facca, Sylvain Gioux, Stefan Catheline, and Amir Nahas "Quantitative full-field transient elastography based on digital holography", Proc. SPIE 11645, Optical Elastography and Tissue Biomechanics VIII, 116450A (5 March 2021); https://doi.org/10.1117/12.2578581

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KEYWORDS

Elastography

Digital holography

Wave propagation

Cameras

Mach-Zehnder interferometers

Natural surfaces

Optical coherence tomography

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