Paper
28 February 2021 Construction of breast cancer photoacoustic imaging model based on COMSOL
Author Affiliations +
Proceedings Volume 11781, 4th Optics Young Scientist Summit (OYSS 2020); 117810P (2021) https://doi.org/10.1117/12.2591388
Event: Optics Frontier: Optics Young Scientist Summit, 2020, Ningbo, China
Abstract
Human female mammary gland is by skin, fibrous tissue, mammary gland and adipose composition, breast cancer is the malignant tumor that occurs in mammary gland epithelial tissue. Mammary gland is not an important organ to maintain human life activities. Breast cancer in situ is not fatal. However, due to the loss of the characteristics of normal cells, the cells are loosely connected and easy to fall off. Once cancer cells are shed, free cancer cells can spread throughout the body with blood or lymph, forming metastases and endangering life. At present, breast cancer has become a common tumor threatening women's physical and mental health. Therefore, studying the interaction of laser with breast tissue and breast tumor has important theoretical and practical significance for the treatment of breast cancer. For this reason, this study developed a two-dimensional numerical simulation model based on finite element using COMSOL Multiphysics, a commercial finite element simulation software, which studied the transmission and heat transfer of light in breast cancer patients. In this study, the model consists of four parts: 1) Water layer; 2) Breast; 3) Breast tumor; 4) short pulse laser source (wavelength: 840nm). The laser point source is located in the middle of the water layer above the breast tissue to irradiate the breast and the tumor. The propagation of light in breast and tumor was simulated by solving the diffusion equation. The temperature changes of breast tissue and breast tumor were obtained by solving the biological heat transfer equation. This study is helpful to understand the transmission of light in human breast and breast tumor as well as the interaction between the two, and has certain theoretical guiding significance for the research and treatment of breast cancer.
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Xianlin Song, Yuli Li, Ao Teng, Zhipeng Zhang, Qiming He, Jinhong Zhang, Aojie Zhao, Bo Li, Zihao Li, Jianshuang Wei, and Lingfang Song "Construction of breast cancer photoacoustic imaging model based on COMSOL", Proc. SPIE 11781, 4th Optics Young Scientist Summit (OYSS 2020), 117810P (28 February 2021); https://doi.org/10.1117/12.2591388
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