Quantification of total haemoglobin concentrations in human whole-blood based on the optical density with spectroscopic optical coherence tomography

Carlos Cuartas-Vélez; Colin Veenstra; Saskia Kruitwagen; Wilma Petersen; Nienke Bosschaart

doi:10.1117/12.2616058

9 December 2021 Quantification of total haemoglobin concentrations in human whole-blood based on the optical density with spectroscopic optical coherence tomography

Carlos Cuartas-Vélez, Colin Veenstra, Saskia Kruitwagen, Wilma Petersen, Nienke Bosschaart

Author Affiliations +

Proceedings Volume 11924, Optical Coherence Imaging Techniques and Imaging in Scattering Media IV; 119240R (2021) https://doi.org/10.1117/12.2616058
Event: European Conferences on Biomedical Optics, 2021, Online Only

Abstract

We present a novel processing technique to retrieve total haemoglobin concentrations with spectroscopic optical coherence tomography data based on numerical optimization of the optical density. We validated our method with ex-vivo human whole blood.

Citation Download Citation

Carlos Cuartas-Vélez, Colin Veenstra, Saskia Kruitwagen, Wilma Petersen, and Nienke Bosschaart "Quantification of total haemoglobin concentrations in human whole-blood based on the optical density with spectroscopic optical coherence tomography", Proc. SPIE 11924, Optical Coherence Imaging Techniques and Imaging in Scattering Media IV, 119240R (9 December 2021); https://doi.org/10.1117/12.2616058

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