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14 March 2023 High-speed adaptive optics partially confocal ophthalmoscope based on Digital Micromirror Device (DMD)
Soohyun Lee, Stacey S. Choi, Ratheesh K. Meleppat, Robert J. Zawadzki, Nathan Doble
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Proceedings Volume 12360, Ophthalmic Technologies XXXIII; 1236008 (2023) https://doi.org/10.1117/12.2650802
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
A high-speed adaptive optics (AO) partially-confocal ophthalmoscope using a digital micromirror device (DMD) and high-speed 2D CMOS camera is presented. The system allows for easy control of the trade-off between image acquisition rate and contrast by applying different illumination patterns on the DMD. The camera is synchronized with the DMD projecting multi-spot patterns on the human retina, which is pre-corrected by AO, for parallel scanning. Frame acquisition rates up to 250 fps was achieved this applying multi-spot scheme, with the contrast improving 2-3 fold compared to standard flood illumination. Partially confocal images of the human retina showed cone and rod photoreceptors over a range of retinal eccentricities.
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Soohyun Lee, Stacey S. Choi, Ratheesh K. Meleppat, Robert J. Zawadzki, and Nathan Doble "High-speed adaptive optics partially confocal ophthalmoscope based on Digital Micromirror Device (DMD)", Proc. SPIE 12360, Ophthalmic Technologies XXXIII, 1236008 (14 March 2023); https://doi.org/10.1117/12.2650802
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KEYWORDS
Digital micromirror devices
Adaptive optics
Retina
Confocal laser scanning microscopy
Retinal scanning
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