All-in-one wireless bioelectronics for continuous monitoring of salivary electrolytes (Conference Presentation)

Hyo-Ryoung Lim; Woon-Hong Yeo

doi:10.1117/12.2656951

27 April 2023 All-in-one wireless bioelectronics for continuous monitoring of salivary electrolytes (Conference Presentation)

Hyo-Ryoung Lim, Woon-Hong Yeo

Author Affiliations +

Proceedings Volume 12485, Nano-, Bio-, Info-Tech Sensors, and Wearable Systems 2023; 1248503 (2023) https://doi.org/10.1117/12.2656951
Event: SPIE Smart Structures + Nondestructive Evaluation, 2023, Long Beach, California, United States

Abstract

Monitoring electrolytes is critical for newborns and babies in the intensive care unit. However, the gold standard methods use a blood draw, which is painful and only offers discrete measures. Here, we introduce a smart, wireless, bioelectronic pacifier for salivary electrolyte monitoring of neonates, which can detect real-time continuous sodium and potassium levels without a blood draw. The miniature system facilitates the seamless integration of the ultralight and low-profile device with a commercial pacifier without additional fixtures or structural modifications. The portable device includes ion-selective sensors, flexible circuits, and microfluidic channels, allowing non-invasive electrolyte monitoring. The flexible microfluidic channel enables continuous and efficient saliva collection from the mouth. In vivo study with neonates in the intensive care unit captures the device's feasibility and performance in the natural saliva-based detection of the critical electrolytes.

Conference Presentation

Citation Download Citation

Hyo-Ryoung Lim and Woon-Hong Yeo "All-in-one wireless bioelectronics for continuous monitoring of salivary electrolytes (Conference Presentation)", Proc. SPIE 12485, Nano-, Bio-, Info-Tech Sensors, and Wearable Systems 2023, 1248503 (27 April 2023); https://doi.org/10.1117/12.2656951

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