Depth perception and imaging of disease phantoms via polarimetry

Xinxian Zhang; Nan Zeng; Hui Ma

doi:10.1117/12.3047620

5 December 2024 Depth perception and imaging of disease phantoms via polarimetry

Xinxian Zhang, Nan Zeng, Hui Ma

Proceedings Volume 13418, Fifteenth International Conference on Information Optics and Photonics (CIOP 2024); 1341810 (2024) https://doi.org/10.1117/12.3047620
Event: 15th International Conference on Information Optics and Photonics (CIOP2024), 2024, Xi’an, China

Abstract

Acquiring depth information of diseases is crucial for guiding treatments such as drug penetration and disease excision. This study focuses on three types of diseases—fibrosis (FT), organelle proliferation (OPT), and pigmentation (PT)—and constructs tissue phantoms that can quantitatively simulate and regulate the depth of diseases under the detection surface. Starting with the FT phantom, this study combines degree of polarization (DoP) and anisotropy polarization basic parameters (PBPs) to establish depth-sensitive polarization feature parameters (DSPFPs). Compared to existing PBPs, DSPFPs achieve superior depth-resolved imaging results. Furthermore, for multiple disease types in shallow layers, this study establishes the Ct parameter for FT diseases, the Rb parameter for OPT diseases, and the RV parameter for PT diseases. These DSPFPs exhibit excellent depth-sensing capabilities for their target disease types and demonstrate some generalization for non-target disease types.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Xinxian Zhang, Nan Zeng, and Hui Ma "Depth perception and imaging of disease phantoms via polarimetry", Proc. SPIE 13418, Fifteenth International Conference on Information Optics and Photonics (CIOP 2024), 1341810 (5 December 2024); https://doi.org/10.1117/12.3047620

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