Monitoring of temperature distribution in tissues with optoacoustic technique in real time

Kirill V. Larin; Irina V. Larina; Massoud Motamedi; Rinat O. Esenaliev

doi:10.1117/12.386336

19 May 2000 Monitoring of temperature distribution in tissues with optoacoustic technique in real time

Kirill V. Larin, Irina V. Larina, Massoud Motamedi, Rinat O. Esenaliev

Proceedings Volume 3916, Biomedical Optoacoustics; (2000) https://doi.org/10.1117/12.386336
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

To improve the safety and efficacy of thermal therapy, it is often necessary to map tissue temperature in real time with submillimeter spatial resolution in order to accurately control the boundaries of heated regions and minimize thermal damage to surrounding normal tissues. Current imaging modalities fail to monitor tissue temperature in real time with high resolution and accuracy. We propose to use optoacoustic techniques for accurate, real-time monitoring of tissue temperature with high spatial resolution. Our previous studies demonstrated that the efficiency of optoacoustic wave generation in tissues increases linearly with temperature during uniform heating. In this study, we induced temperature gradients in treated samples and monitor temperature distribution in tissue using optoacoustic technique. Fundamental harmonic of Q-switched Nd:YAG laser was used for optoacoustic wave generation and probing of tissue temperature while the tissue temperature was also monitored with a multisensor temperature probe inserted in the samples. Good agreement between optoacoustic dat and the tissue temperature as recorded via the probe was demonstrated. The optoacoustic techniques was capable of real-time temperature distribution monitoring with submillimeter resolution and high accuracy.

Citation Download Citation

Kirill V. Larin, Irina V. Larina, Massoud Motamedi, and Rinat O. Esenaliev "Monitoring of temperature distribution in tissues with optoacoustic technique in real time", Proc. SPIE 3916, Biomedical Optoacoustics, (19 May 2000); https://doi.org/10.1117/12.386336

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available