Lymphoid tissue during irradiation of tumors with pulsing laser's radiation

Konstantin G. Moskalik M.D.

doi:10.1117/12.472532

27 June 2002 Lymphoid tissue during irradiation of tumors with pulsing laser's radiation

Konstantin G. Moskalik M.D.

Proceedings Volume 4617, Laser Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical; (2002) https://doi.org/10.1117/12.472532
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

The structure of the regional lymph nodes and the thymus was studied in the experiments upon the mice of the line C57BL with the subcutaneous interwoven melanoma B₁₆ in the periods from one hour to 12 days after the radiation of melanoma with one irradiation impulse of the Nd laser with the energy density of 400 J/cm². During the first 3 days after the irradiation of tumor with laser radiation the impoverishment of lymph nodes and thymus with lymphocytes takes place because of their intensified migration from these organs to the blood channel. Then one can see the restoration of the lymph nodes and thymus structure. The restoration of lymphopoiesis in the lymph nodes went on in the first place because of the poiesis in the follicles which consist of B-lymphocytes. Consequently, the lymphoid tissue plays a great role in the reorganization of the immunological status of the organism. Reorganization can be seen during the treatment of tumors with laser radiation, and it takes place in the first instance because of the reinforcement of the humoral immunity.

Citation Download Citation

Konstantin G. Moskalik M.D. "Lymphoid tissue during irradiation of tumors with pulsing laser's radiation", Proc. SPIE 4617, Laser Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical, (27 June 2002); https://doi.org/10.1117/12.472532

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