Modeling the temperature rise during diode laser welding of the cornea

Francesca Rossi; Roberto Pini

doi:10.1117/12.610814

18 April 2005 Modeling the temperature rise during diode laser welding of the cornea

Francesca Rossi, Roberto Pini

Author Affiliations +

Proceedings Volume 5688, Ophthalmic Technologies XV; (2005) https://doi.org/10.1117/12.610814
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

We present the results of a model describing the temperature rise in the cornea during low power diode laser welding of the stroma to induce the repair of corneal wounds. A bi-dimensional model of the anterior segment of the porcine eye was developed. A full thickness corneal cut was considered to be filled by a solution of Indocyanine Green (ICG) in distilled water, which is used to topically enhance the optical absorption of the corneal stroma at the diode laser emission wavelength (810 nm). The typical irradiation conditions used for laser-induced suturing in the transplant of the cornea were considered. The Finite Element Method was used to solve the bio-heat equation inside the cornea wound by using the proper thermal parameters of porcine ocular tissues, providing the thermal response during and shortly after laser treatment. Results indicated a relatively modest temperature increase (of about 20°C), that was spatially confined within the region stained by the chromophore. Calculation of the Arrhenius integral showed no significant thermal damage in the region of the laser-treated wound, thus supporting our previous experimental observations and histological examinations performed on animal models.

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Francesca Rossi and Roberto Pini "Modeling the temperature rise during diode laser welding of the cornea", Proc. SPIE 5688, Ophthalmic Technologies XV, (18 April 2005); https://doi.org/10.1117/12.610814

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KEYWORDS

Cornea

Semiconductor lasers

Tissues

Absorption

Eye models

Laser welding

Animal model studies

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