Visualization and quantitative analysis of lung microstructure using micro CT images

Tetsuo Yamamoto; Mitsuru Kubo; Yoshiki Kawata; Noboru Niki; Masashi Fujii; Yoshihiro Nakaya; Eisuke Matsui; Hironobu Ohmatsu; Noriyuki Moriyama

doi:10.1117/12.595043

14 April 2005 Visualization and quantitative analysis of lung microstructure using micro CT images

Tetsuo Yamamoto, Mitsuru Kubo, Yoshiki Kawata, Noboru Niki, Masashi Fujii, Yoshihiro Nakaya, Eisuke Matsui, Hironobu Ohmatsu, Noriyuki Moriyama

Author Affiliations +

Proceedings Volume 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images; (2005) https://doi.org/10.1117/12.595043
Event: Medical Imaging, 2005, San Diego, California, United States

Abstract

Micro CT system is developed for lung function analysis at a high resolution of the micrometer order (up to 5μm in spatial resolution). This system reveals the lung distal structures such as interlobular septa, terminal bronchiole, respiratory bronchiole, alveolar duct, and alveolus. In order to visualize lung 3-D microstructures using micro CT images and to analyze them, this research presents a computerized approach. This approach is applied for to micro CT images of human lung tissue specimens that were obtained by surgical excision and were kept in the state of the inflated fixed lung. This report states a wall area such as bronchus wall and alveolus wall about the extraction technique by using the surface thinning process to analyze the lung microstructures from micro CT images measured by the new-model micro CT system.

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Tetsuo Yamamoto, Mitsuru Kubo, Yoshiki Kawata, Noboru Niki, Masashi Fujii, Yoshihiro Nakaya, Eisuke Matsui, Hironobu Ohmatsu, and Noriyuki Moriyama "Visualization and quantitative analysis of lung microstructure using micro CT images", Proc. SPIE 5746, Medical Imaging 2005: Physiology, Function, and Structure from Medical Images, (14 April 2005); https://doi.org/10.1117/12.595043

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