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All extended optical systems with aberrations suffer from anisoplanatism effect. In this presentation we investigate anisoplanatism in human eye. For that purpose we use a reference source (beacon) obtained by focusing of a dim laser beam on the retina and consider increasing the retina resolution within anisoplanatic angle by means of ideal wavefront corrector and a real bimorph flexible one. The numerical simulations of isoplanatic patch size of human retina were made for different beacon positions and based on the aberrations measured by means of custom wavefront-guided aberrometer. We found out that in particular human eye the existence of optimal correction directions is possible. As the behavior of Zernike coefficients varies from subject to subject the existence of optimal correction angle is a feature of a particular eye. We also estimated the contribution of low-order and high-order aberrations in anisoplanatism effect for the subjects we measured. We found out that aberrations with strongly variable amplitude across the visual field have effect on the isoplanatic patch size most. In this paper we illustrated the isoplanatic patch enlargement with variation of beacon position by presenting two-dimensional retina and test object images. Also anisoplanatism in two-layer human eye model has been discussed. As the main part of the eye's aberrations is induced by the surfaces of the cornea and the crystal lens, our model consists of two thin phase screens that correspond to the cornea and the lens. Then we used such two-layer model to minimize residual mean-square error of correction by means of just one applied corrector.
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Alexander Dubinin, Tatyana Cherezova, Alexey Belyakov, Alexis Kudryashov, "Anisoplanatism in human retina imaging," Proc. SPIE 5894, Advanced Wavefront Control: Methods, Devices, and Applications III, 589409 (22 August 2005); https://doi.org/10.1117/12.619429