Monte-Carlo simulation of photon trans-illumination time of flight

Paulino Vacas-Jacques; Marija Strojnik; Gonzalo Paez

doi:10.1117/12.728039

18 July 2007 Monte-Carlo simulation of photon trans-illumination time of flight

Paulino Vacas-Jacques, Marija Strojnik, Gonzalo Paez

Proceedings Volume 6631, Novel Optical Instrumentation for Biomedical Applications III; 663114 (2007) https://doi.org/10.1117/12.728039
Event: European Conferences on Biomedical Optics, 2007, Munich, Germany

Abstract

We present a Monte Carlo (MC) program for determining the temporal behavior of radiation in turbid media, in general, and a tissue, in particular. An object-oriented MC program with flexibility for parallel implementation, and for performing stochastic analysis, is described. We determine the temporal probability distribution functions for three tissues: I ) a lipid-based tissue phantom, II ) a healthy dental tissue, and III ) a dental tissue with caries. The expected time of flight for transmitted radiation is calculated. Signal-to-noise ratios (SNR) are then obtained for several temporal thresholds. By restraining the time threshold, a two orders of magnitude increase in SNR is predicted. A multivariate analysis is finally proposed to complement the discrimination process, necessary for trans-illumination interferometry.

Citation Download Citation

Paulino Vacas-Jacques, Marija Strojnik, and Gonzalo Paez "Monte-Carlo simulation of photon trans-illumination time of flight", Proc. SPIE 6631, Novel Optical Instrumentation for Biomedical Applications III, 663114 (18 July 2007); https://doi.org/10.1117/12.728039

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