X-ray fluorescence camera for biomedical imaging

Hiroshi Matsukiyo; Eiichi Sato; Purkhet Abderyim; Akihiro Osawa; Toshiyuki Enomoto; Manabu Watanabe; Jiro Nagao M.D.; Seiichiro Nomiya; Koetsu Sato; Akira Ogawa; Shigehiro Sato; Toshio Ichimaru

doi:10.1117/12.795890

3 September 2008 X-ray fluorescence camera for biomedical imaging

Hiroshi Matsukiyo, Eiichi Sato, Purkhet Abderyim, Akihiro Osawa, Toshiyuki Enomoto, Manabu Watanabe, Jiro Nagao M.D., Seiichiro Nomiya, Koetsu Sato, Akira Ogawa, Shigehiro Sato, Toshio Ichimaru

Author Affiliations +

Proceedings Volume 7080, Penetrating Radiation Systems and Applications IX; 708007 (2008) https://doi.org/10.1117/12.795890
Event: Optical Engineering + Applications, 2008, San Diego, California, United States

Abstract

X-Ray Fluorescence (XRF) analysis is useful for measuring density distributions of contrast media in vivo. An XRF camera was developed to carry out mapping for iodine-based contrast media used in medical angiography. In this camera, objects are exposed by an x-ray beam formed using a 3.0-mm-diameter lead hole. Next, cerium K-series characteristic x-rays are absorbed effectively by iodine media in objects, and iodine fluorescences are produced from the objects. Iodine Kα fluorescences are selected out using a 58-μm-thick stannum filter and are detected by a cadmium telluride (CdTe) detector. Kα rays are discriminated out by a multichannel analyzer (MCA), and photon number is counted by a counter board (CB). The objects are moved and scanned using an x-y stage driven by a two-stage controller, and x-ray images obtained by iodine mapping are shown in a personal computer (PC) monitor. In particular, iodine fluorescences were produced from remanent iodine elements in a cancer region of a rabbit ear.

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Hiroshi Matsukiyo, Eiichi Sato, Purkhet Abderyim, Akihiro Osawa, Toshiyuki Enomoto, Manabu Watanabe, Jiro Nagao M.D., Seiichiro Nomiya, Koetsu Sato, Akira Ogawa, Shigehiro Sato, and Toshio Ichimaru "X-ray fluorescence camera for biomedical imaging", Proc. SPIE 7080, Penetrating Radiation Systems and Applications IX, 708007 (3 September 2008); https://doi.org/10.1117/12.795890

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