Atmospheric pressure femtosecond laser imaging mass spectrometry

Yves Coello; Tissa C. Gunaratne; Marcos Dantus

doi:10.1117/12.808252

23 February 2009 Atmospheric pressure femtosecond laser imaging mass spectrometry

Yves Coello, Tissa C. Gunaratne, Marcos Dantus

Proceedings Volume 7182, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII; 71821W (2009) https://doi.org/10.1117/12.808252
Event: SPIE BiOS, 2009, San Jose, California, United States

Abstract

We present a novel imaging mass spectrometry technique that uses femtosecond laser pulses to directly ionize the sample. The method offers significant advantages over current techniques by eliminating the need of a laser-absorbing sample matrix, being suitable for atmospheric pressure sampling, and by providing 10μm resolution, as demonstrated here with a chemical image of vegetable cell walls.

Citation Download Citation

Yves Coello, Tissa C. Gunaratne, and Marcos Dantus "Atmospheric pressure femtosecond laser imaging mass spectrometry", Proc. SPIE 7182, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VII, 71821W (23 February 2009); https://doi.org/10.1117/12.808252

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