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We provide theoretical validation of the brain-functional detection using multidistance probe arrangement based
on Monte Carlo simulations of five-layered model in which both scattering and absorption changes occur. It
shows that optimized multidistance probe arrangement can be effective in removing interferences by scattering
and absorption changes in upper layers and extracting absorption change in the gray matter layer. Using newly
designed probes and their holder system, both conventional and proposed fNIRS measurements were implemented
with non-functional (body and head movements and respiratory change) and functional (finger opposition) tasks.
Artifacts, even if it correlate with task sequence, were well reduced. Functional signals were well localized at
lateralized cerebral functional area.
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