Paper
8 May 2012 New imaging technique using degree of polarization for the study of polarimetric properties for non-invasive biomedical diagnostic
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Abstract
This research proposes a new imaging technique for near real time multispectral acquisition using CCD RGB cameras of the so called "Degree Of Polarization" (DOP) in polarimetry for future clinical investigation. The aim of exploiting the DOP as the contrast element is to demonstrate that the elliptical DOP provides more information characterizing complex medium than the more traditional linear and circular ones. The system considers an incoherent input white light beam and opportunely calibrated nematic crystals (LCVR), so no mechanical tools are necessary. The particular features of the system indicate it to be the perfect candidate for a new imaging system considering in-vivo (as well as ex-vivo) non invasive superficial diagnostic for medical application as dermatologic diagnostics, since no type of sample preparation is necessary, i.e. tissue biopsy, radiation or contrast agent injection. Thus the biomedical application of this method suggests a simple, direct, fast and also easily exploitable future employment, as a desirable mean for clinical investigation but also for digital recognition in biometrics. Further new elements to improve the model of light scattering and matter-light interaction will be acquired, in particular considering a very complete characterization of the system response using latex microspheres suspension to simulate turbid media with different concentration.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Isabella Chiara Buscemi, Steve Guyot, and Jacques Lemoine "New imaging technique using degree of polarization for the study of polarimetric properties for non-invasive biomedical diagnostic", Proc. SPIE 8427, Biophotonics: Photonic Solutions for Better Health Care III, 842706 (8 May 2012); https://doi.org/10.1117/12.922676
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Cited by 3 scholarly publications.
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KEYWORDS
Polarization

Calibration

Diagnostics

Polarimetry

Biomedical optics

CCD cameras

Light scattering

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