Quantitative and qualitative analysis of fluorescent substances and binary mixtures by use of shifted excitation Raman difference spectroscopy

Boris L. Volodin; Sergei Dolgy; Chad Lieber; Huawen Wu; William Yang

doi:10.1117/12.2008241

22 March 2013 Quantitative and qualitative analysis of fluorescent substances and binary mixtures by use of shifted excitation Raman difference spectroscopy

Boris L. Volodin, Sergei Dolgy, Chad Lieber, Huawen Wu, William Yang

Author Affiliations +

Proceedings Volume 8572, Advanced Biomedical and Clinical Diagnostic Systems XI; 857211 (2013) https://doi.org/10.1117/12.2008241
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Shifted Excitation Raman Difference Spectroscopy (SERDS) implemented with two wavelength-stabilized laser diodes with fixed wavelength separation is discussed as an effective method for dealing with the effects of fluorescence in Raman spectroscopic analysis. In this presentation we discuss the results of both qualitative and quantitative SERDS analysis of a variety of strongly fluorescing samples, including binary liquid mixtures. This application is enabled by the Volume Bragg Grating® (VBG®) technology, which allows manufacturing of compact low-cost high-power laser sources, suitable for extending the SERDS methodology to portable Raman spectrometers.

Citation Download Citation

Boris L. Volodin, Sergei Dolgy, Chad Lieber, Huawen Wu, and William Yang "Quantitative and qualitative analysis of fluorescent substances and binary mixtures by use of shifted excitation Raman difference spectroscopy", Proc. SPIE 8572, Advanced Biomedical and Clinical Diagnostic Systems XI, 857211 (22 March 2013); https://doi.org/10.1117/12.2008241

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