Thermoacoustic imaging of fresh prostates up to 6-cm diameter

S. K. Patch; E. Hanson; M. Thomas; H. Kelly; K. Jacobsohn; W. A. See

doi:10.1117/12.2001896

4 March 2013 Thermoacoustic imaging of fresh prostates up to 6-cm diameter

S. K. Patch, E. Hanson, M. Thomas, H. Kelly, K. Jacobsohn, W. A. See

Proceedings Volume 8581, Photons Plus Ultrasound: Imaging and Sensing 2013; 85812K (2013) https://doi.org/10.1117/12.2001896
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Thermoacoustic (TA) imaging provides a novel contrast mechanism that may enable visualization of cancerous lesions which are not robustly detected by current imaging modalities. Prostate cancer (PCa) is the most notorious example. Imaging entire prostate glands requires 6 cm depth penetration. We therefore excite TA signal using submicrosecond VHF pulses (100 MHz). We will present reconstructions of fresh prostates imaged in a well-controlled benchtop TA imaging system. Chilled glycine solution is used as acoustic couplant. The urethra is routinely visualized as signal dropout; surgical staples formed from 100-micron wide wire bent to 3 mm length generate strong positive signal.

Citation Download Citation

S. K. Patch, E. Hanson, M. Thomas, H. Kelly, K. Jacobsohn, and W. A. See "Thermoacoustic imaging of fresh prostates up to 6-cm diameter", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85812K (4 March 2013); https://doi.org/10.1117/12.2001896

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KEYWORDS

Prostate

Signal generators

Linear filtering

Transducers

Tissues

Tomography

Blood

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