Zinc oxide nanostructures as low-cost templates for neuronal circuit

A. Kritharidou; Z. Georgoussi; C. Tsamis; E. Makarona

doi:10.1117/12.2017620

28 May 2013 Zinc oxide nanostructures as low-cost templates for neuronal circuit

A. Kritharidou, Z. Georgoussi, C. Tsamis, E. Makarona

Proceedings Volume 8765, Bio-MEMS and Medical Microdevices; 87650G (2013) https://doi.org/10.1117/12.2017620
Event: SPIE Microtechnologies, 2013, Grenoble, France

Abstract

ZnO nanostructures were explored as templates for the development of topography-mediated neuronal cultures. Nanostructures of varying features were produced on 4” Si substrates via a rapid, facile and low-cost technique that allows the systematic investigation of nanotopographically-mediated formation of neuronal cultures. The developed ZnO-nanowire based templates were seeded with Neuro-2A mouse neuroblastoma cells and their viability over the course of 1 to 4 days was assessed. Our studies demonstrate that the ZnO-templates can support neuronal cell growth and proliferation suggesting that ZnO substrate can be used for the development of neuronal cell-based platform technologies.

Citation Download Citation

A. Kritharidou, Z. Georgoussi, C. Tsamis, and E. Makarona "Zinc oxide nanostructures as low-cost templates for neuronal circuit", Proc. SPIE 8765, Bio-MEMS and Medical Microdevices, 87650G (28 May 2013); https://doi.org/10.1117/12.2017620

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