Angio-OCT as a noninvasive tool for three-dimensional vascular network visualization in retinal diseases

D. Bukowska; D. Ruminski; B. L. Sikorski; I. Gorczynska; D. Borycki; M. Szkulmowski; M. Wojtkowski

doi:10.1117/12.2032635

18 June 2013 Angio-OCT as a noninvasive tool for three-dimensional vascular network visualization in retinal diseases

D. Bukowska, D. Ruminski, B. L. Sikorski, I. Gorczynska, D. Borycki, M. Szkulmowski, M. Wojtkowski

Proceedings Volume 8802, Optical Coherence Tomography and Coherence Techniques VI; 88020H (2013) https://doi.org/10.1117/12.2032635
Event: European Conferences on Biomedical Optics, 2013, Munich, Germany

Abstract

In this paper we demonstrate applicability of intensity-based optical coherence tomography technique for noninvasive visualization of 3D retinal microcapillary network. The study was performed with ultra high resolution and high speed (180,000 Ascans/sec) spectral optical coherence tomography (SOCT). New scanning protocols and data processing algorithms have been introduced to visualize microcapillary network. Moreover, results obtained in the eyes of healthy volunteers and patients with eye diseases were compared with fluorescein angiography. Presented report shows that SOCT is well suited for visualization of 3D retinal capillary network in the healthy and pathologic eyes as well. Obtained results demonstrate high correspondence with fluorescein angiography, without using any contrast agents. Our data suggest that intensity-based SOCT has potential in the early diagnosis of the retinal vascular diseases.

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D. Bukowska, D. Ruminski, B. L. Sikorski, I. Gorczynska, D. Borycki, M. Szkulmowski, and M. Wojtkowski "Angio-OCT as a noninvasive tool for three-dimensional vascular network visualization in retinal diseases", Proc. SPIE 8802, Optical Coherence Tomography and Coherence Techniques VI, 88020H (18 June 2013); https://doi.org/10.1117/12.2032635

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KEYWORDS

Optical coherence tomography

Visualization

Angiography

Eye

Capillaries

3D visualizations

Polishing

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