Integrated optofluidic label-free biosensors using a silicon-nitride-based coupled-resonator optical waveguide

Jiawei Wang; Zhanshi Yao; Andrew W. Poon

doi:10.1117/12.2214100

1 March 2016 Integrated optofluidic label-free biosensors using a silicon-nitride-based coupled-resonator optical waveguide

Jiawei Wang, Zhanshi Yao, Andrew W. Poon

Author Affiliations +

Proceedings Volume 9750, Integrated Optics: Devices, Materials, and Technologies XX; 975014 (2016) https://doi.org/10.1117/12.2214100
Event: SPIE OPTO, 2016, San Francisco, California, United States

Abstract

In this paper, we report our recent progress in silicon-nitride-based optofluidic label-free biosensors using a surfacefunctionalized coupled-resonator optical waveguide (CROW) in the visible wavelengths. The working principle is based on far-field imaging of the CROW mode-field intensity distributions at a fixed probe wavelength. The imaged pattern variation reflects real-time analyte-binding information on the CROW surfaces. Our surface-functionalized 16- microring CROW reveals six eigenstates with distinctive mode-field intensity distributions. Our proof-of-concept sensing experiment at an arbitrarily chosen probe wavelength within the CROW transmission band shows a detection of streptavidin concentration down to 40 ng/ml.

Citation Download Citation

Jiawei Wang, Zhanshi Yao, and Andrew W. Poon "Integrated optofluidic label-free biosensors using a silicon-nitride-based coupled-resonator optical waveguide", Proc. SPIE 9750, Integrated Optics: Devices, Materials, and Technologies XX, 975014 (1 March 2016); https://doi.org/10.1117/12.2214100

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