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Refractive errors commonly cause vision impairments; current treatments are temporary and/or involve side-effects. We performed electromechanical reshaping (EMR), a potential laser eye surgery alternative, to determine its effect on reshaping corneal curvature in ex vivo rabbit corneas. Optical coherence tomography (OCT) was performed to ensure corneal curvature change. Second harmonic generation (SHG) was used to determine if collagen damage occurred. After EMR, shape change was visualized with OCT while SHG indicated weaker collagen signals in certain regions. EMR is a potential treatment for refractive errors. However, more experiments are required to determine efficacy and potential for clinical application.
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Kelly Hernandez, Katelyn Dilley, Zhongping Chen, Sehwan Kim, Michael Hill, Brian Wong, "Exploration of electromechanical reshaping of rabbit cornea," Proc. SPIE PC11941, Ophthalmic Technologies XXXII, PC1194107 (7 March 2022); https://doi.org/10.1117/12.2610383