Development of a clinical prototype single input polarization-sensitive optical coherence tomography for imaging wound healing process

Athira B.S.; Peijun Tang; Nhan Le; Bazil Hyder; Ruikang K. Wang

doi:10.1117/12.2651459

17 March 2023 Development of a clinical prototype single input polarization-sensitive optical coherence tomography for imaging wound healing process

Athira B.S., Peijun Tang, Nhan Le, Bazil Hyder, Ruikang K. Wang

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Proceedings Volume PC12352, Photonics in Dermatology and Plastic Surgery 2023; PC123520L (2023) https://doi.org/10.1117/12.2651459
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

This paper presents a hand-held single-mode fiber-based polarization-sensitive optical coherence tomography (PS-OCT) system with a single input polarization state. One drawback of this system is that the polarization becomes arbitrary, which can be solved by placing a polarization controller in the sample arm. A calibration target with an azimuthally varying optic axis integrated with the handheld probe will provide an absolute orientation axis measurement. This significantly reduces cost, time and availability of PS-OCT for clinical applications. With the home-built PS-OCT, we investigate the reorganization of collagen and blood vessel in a wound on the dorsal side of the human hand.

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Citation Download Citation

Athira B.S., Peijun Tang, Nhan Le, Bazil Hyder, and Ruikang K. Wang "Development of a clinical prototype single input polarization-sensitive optical coherence tomography for imaging wound healing process", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC123520L (17 March 2023); https://doi.org/10.1117/12.2651459

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KEYWORDS

Polarization

Optical coherence tomography

Coherence imaging

Wound healing

Image processing

Prototyping

Birefringence

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