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We developed a multimodal non-linear optical super resolution imaging platform for studying metabolic changes during aging and diseases. This platform integrates deuterium probed Stimulated Raman scattering (DO-SRS), multiphoton fluorescence (MPF), and second harmonic generation (SHG) into a super resolution multimolecular microscopy.
Lingyan Shi
"Multimodal non-linear optical super resolution imaging of metabolism during aging and diseases", Proc. SPIE PC12373, Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis, PC1237307 (6 March 2023); https://doi.org/10.1117/12.2660202
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Lingyan Shi, "Multimodal non-linear optical super resolution imaging of metabolism during aging and diseases," Proc. SPIE PC12373, Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis, PC1237307 (6 March 2023); https://doi.org/10.1117/12.2660202