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Diffuse reflectance spectroscopy needs to tailor the light-tissue interaction model for the geometry of probing. Single-fiber reflectance (SfR) suitable for interstitial probing and center-illumination-area-detection (CIAD) convenient for non-contact sensing are two challenging geometries. We report progresses on modeling light-tissue interactions applicable to those two geometries. These progresses have been applied to interstitial monitoring of cerebral oxygenation changes, non-contact sensing of glucose concentration in turbid medium, and depth-resolved assessing of myoglobin oxygenation in beef, etc. A new analytical path indicating the random lasing threshold as is facilitated by modeling light-tissue interaction in a scattering medium with gain will also be discussed.
Daqing Piao
"Recent progresses on understanding light interaction with turbid medium towards sensing (Conference Presentation)", Proc. SPIE PC12394, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XX, PC1239401 (16 March 2023); https://doi.org/10.1117/12.2651668
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Daqing Piao, "Recent progresses on understanding light interaction with turbid medium towards sensing (Conference Presentation)," Proc. SPIE PC12394, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XX, PC1239401 (16 March 2023); https://doi.org/10.1117/12.2651668