Hydrophobic marking line used to eliminate the edge effect in a microfluidic point-of-care testing device

Li Jingmin; Li Xia; Liu Ziyang; Liang Chao; Liu Chong

doi:10.1117/1.JMM.16.1.015001

2 January 2017 Hydrophobic marking line used to eliminate the edge effect in a microfluidic point-of-care testing device

Li Jingmin, Li Xia, Liu Ziyang, Liang Chao, Liu Chong

Author Affiliations +

Journal of Micro/Nanolithography, MEMS, and MOEMS, Vol. 16, Issue 1, 015001 (January 2017). https://doi.org/10.1117/1.JMM.16.1.015001

Abstract

The traversal rate for the liquid medium near a point-of-care testing (POCT) device microfluidic channel edge is faster than that through the body of the channel, which makes the fluid front meniscus becomes concave rather than convex or flat. The concave front is unwished due to its influences on quantitative analysis accuracy and the possibility to generate air bubbles. Here, a unique method, named hydrophobic marking line, is demonstrated. This method used a soft pen with hydrophobic ink to draw two lines along the edges of the channel of a POCT device. Results have shown that the marking lines will eliminate the edge effects and generate convex liquid front. The curvature of the liquid front can be changed by adjusting the marking line width or ink solutions.

Citation Download Citation

Li Jingmin, Li Xia, Liu Ziyang, Liang Chao, and Liu Chong "Hydrophobic marking line used to eliminate the edge effect in a microfluidic point-of-care testing device," Journal of Micro/Nanolithography, MEMS, and MOEMS 16(1), 015001 (2 January 2017). https://doi.org/10.1117/1.JMM.16.1.015001

Received: 17 July 2016; Accepted: 30 November 2016; Published: 2 January 2017

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