High-dose laser exposure to tissue causes thermal damage and significant changes in tissue optical properties. Samples of porcine dermis and subcutaneous fat were immersed in a temperature-controlled water bath to induce a range of thermal damage. Temperature history was recorded to quantify the damage with the Arrhenius integral. Samples were then measured in a double integrating sphere setup and optical coefficients computed using the inverse adding doubling method. The tissues demonstrate non-monotonic changes in optical properties with respect to induced thermal damage. These results will inform medical scenarios and computational models where optical interaction with damaged tissues is expected.
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