Dr. Gary R. Holtom Profile

Dr. Gary R. Holtom

Research Scientist

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Publications (10)

SPIE Journal Paper | 23 May 2014 Open Access

Three-dimensional chemical imaging of skin using stimulated Raman scattering microscopy

Dane Drutis, Thomas Hancewicz, Eugene Pashkovski, Lin Feng, Dawn Mihalov, Gary Holtom, Kavssery Ananthapadmanabhan, X. Sunney Xie, Manoj Misra

JBO, Vol. 19, Issue 11, 111604, (May 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.11.111604

KEYWORDS: Skin, Proteins, 3D image processing, Imaging spectroscopy, Raman spectroscopy, Raman scattering, Microscopy, Visualization, Spectroscopy, Tissues

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Proceedings Article | 9 February 2012 Paper

Towards a tunable fiber source for coherent Raman imaging

Simon Lefrancois, Dan Fu, Gary Holtom, Lingjie Kong, William Wadsworth, Patrick Schneider, Robert Herda, Armin Zach, X. Sunney Xie, Frank Wise

Proceedings Volume 8226, 822620 (2012) https://doi.org/10.1117/12.920187

KEYWORDS: Chromium, Picosecond phenomena, Fiber lasers, Microscopy, Dispersion, Coherence imaging, Raman spectroscopy, Four wave mixing, Fiber amplifiers, Tissues

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Proceedings Article | 26 February 2010 Paper

Short-pulse fiber lasers for Raman microscopies

F. Wise, W. Renninger, S. Lefrancois, K. Kieu, M. Farrar, C, Schaffer, Brian Saar, Gary Holtom, Sunney Xie

Proceedings Volume 7569, 75690I (2010) https://doi.org/10.1117/12.841406

KEYWORDS: Microscopy, Fiber lasers, Picosecond phenomena, Dispersion, Raman spectroscopy, Solitons, Femtosecond phenomena, Amplifiers, Optical parametric oscillators, Pulsed laser operation

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Proceedings Article | 25 February 2009 Paper

Fiber lasers for CARS microscopy

F. Wise, K. Kieu, Brian Saar, Gary Holtom, Sunney Xie

Proceedings Volume 7183, 718318 (2009) https://doi.org/10.1117/12.817128

KEYWORDS: Microscopy, Picosecond phenomena, Fiber lasers, Optical parametric oscillators, Fiber amplifiers, Oscillators, CARS tomography, Amplifiers, Laser systems engineering, Raman spectroscopy

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Proceedings Article | 21 June 2004 Paper

Multichannel multiphoton imaging of metal oxides nanoparticles in biological system

Yuangang Zheng, Gary Holtom, Steven Colson

Proceedings Volume 5323, (2004) https://doi.org/10.1117/12.528337

KEYWORDS: Nanoparticles, Particles, Iron, Oxides, Zinc oxide, Hybrid fiber optics, Metals, Microscopy, Imaging systems, Multichannel imaging systems

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Proceedings Article | 24 April 2001 Paper

Application of coherent antistokes Raman scattering (CARS) to imaging mammalian cells: a means for gaining molecular selectivity in multiphoton imaging

Gary Holtom, Brian Thrall, Thomas Weber, Leyun Zhu, Derek Hopkins, Christopher Parkinson, Steven Colson, John Price, Beek Yoke Chin, Augustine Choi, Terence Risby

Proceedings Volume 4262, (2001) https://doi.org/10.1117/12.424571

KEYWORDS: Luminescence, Raman spectroscopy, Microscopy, Signal detection, Carbon, Particles, CARS tomography, Microscopes, Cell death, Molecular lasers

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Proceedings Article | 10 April 1995 Paper

Femtosecond optical parametric oscillators (OPOs) at 3 micrometersand beyond: design and performance issues related to crystal properties of KTP and similar materials

Gary Holtom, Robert Crowell, Lap Cheng

Proceedings Volume 2379, (1995) https://doi.org/10.1117/12.206500

KEYWORDS: Optical parametric oscillators, Crystals, Ferroelectric materials, Nonlinear crystals, Femtosecond phenomena, Mirrors, Output couplers, Reflectivity, Laser crystals, Phase matching

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Proceedings Article | 17 August 1994 Paper

Near-field fluorescence microscopy and spectroscopy: applications to single chromophores, single proteins, and photosynthetic membranes

Sunney Xie, Errol Allen, Gary Holtom, Robert Dunn, Laurens Mets

Proceedings Volume 2137, (1994) https://doi.org/10.1117/12.182708

KEYWORDS: Luminescence, Near field, Molecules, Proteins, Spatial resolution, Spectroscopy, Chromophores, Picosecond phenomena, Microscopes, Near field optics

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Proceedings Article | 1 May 1990 Paper

Picosecond resolution study of intramolecular energy transfer in lumazine protein

John Lee, Gary Holtom, Dennis O'Kane

Proceedings Volume 1204, (1990) https://doi.org/10.1117/12.17750

KEYWORDS: Proteins, Luminescence, Picosecond phenomena, Energy transfer, Biochemistry, Absorption, Laser spectroscopy, Anisotropy, Biotechnology, Spherical lenses

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Proceedings Article | 1 May 1990 Paper

Artifacts and diagnostics in fast fluorescence measurements

Gary Holtom

Proceedings Volume 1204, (1990) https://doi.org/10.1117/12.17680

KEYWORDS: Luminescence, Picosecond phenomena, Monochromators, Dye lasers, Laser spectroscopy, Biochemistry, Electronics, Polarization, Pulsed laser operation, Light scattering

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Showing 5 of 10 publications

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