Architecture brings together diverse elements to enhance the observer’s measure of esthetics and the convenience of
functionality. Architects often conceptualize synthesis of design elements to invoke the observer’s sense of harmony and
positive affect. How does an observer’s brain respond to harmony of design in interior spaces? One implicit
consideration by architects is the role of guided visual attention by observers while navigating indoors. Prior visual
experience of natural scenes provides the perceptual basis for Gestalt of design elements. In contrast, Gestalt of
organization in design varies according to the architect’s decision. We outline a quantitative theory to measure the
success in utilizing the observer’s psychological factors to achieve the desired positive affect. We outline a unified
framework for perception of geometry and motion in interior spaces, which integrates affective and cognitive aspects of
human vision in the context of anthropocentric interior design. The affective criteria are derived from contemporary
theories of interior design. Our contribution is to demonstrate that the neural computations in an observer’s eye
movement could be used to elucidate harmony in perception of form, space and motion, thus a measure of goodness of
interior design. Through mathematical modeling, we argue the plausibility of the relevant hypotheses.
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