Although oxidative stress is believed to play an important role in numerous diseases, current methods of measuring the oxidative stress level do not provide a consensus on how to quantify and compare the level of oxidative stress. Here, we suggest optical diffraction tomography (ODT) as a label-free cellular oxidative stress level quantification method. ODT measurements of HS68 cells treated with hydrogen peroxide solution showed that the oxidative stress level can be quantified based on the biophysical features from the refractive index (RI) tomogram. Quantifying the cellular oxidative stress based on the RI measurements will provide a direct guideline for the level of cell stresses on both academic and clinical situations.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.