Prof. Jan Laufer Profile

Prof. Jan Laufer

Professor at Martin-Luther-Univ Halle-Wittenberg

SPIE Involvement:

Author | Editor

Publications (55)

Proceedings Article | 20 June 2024 Presentation

A numerical model for quantitative photoacoustic spectroscopy of contrast agents

Marzieh Ezzatpour, Farzin Ghane Golmohamadi, Jan Laufer

Proceedings Volume PC13006, PC130060H (2024) https://doi.org/10.1117/12.3017064

KEYWORDS: 3D modeling, Photoacoustic spectroscopy, Contrast agents, Absorption, Photoacoustic imaging, 3D image processing, Spectroscopy, Acoustics, Wave propagation, Transmittance

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Proceedings Article | 20 June 2024 Presentation

Evaluation of image reconstruction algorithms for quantitative photoacoustic tomography based on limited view data

Guo Tang, Jiaqi Zhu, Felix Lucka, Teemu Sahlström, Ben Cox, Jan Laufer

Proceedings Volume PC13006, PC130060I (2024) https://doi.org/10.1117/12.3017115

KEYWORDS: 3D modeling, Photoacoustic tomography, Model-based design, Image restoration, Data modeling, 3D image reconstruction, Reconstruction algorithms, Tissues, Acoustics, Monte Carlo methods

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Proceedings Article | 20 June 2024 Presentation

Effect of molecular dynamics and internal water contact on the photophysical properties of red pH sensitive proteins

Franz-Josef Schmitt, Amna Shah Mehmood, Christian Tüting, Hoang Trong Phan, Fabian Rieder, Farzin Ghane Golmohamadi, Jan Laufer

Proceedings Volume PC13006, PC130060T (2024) https://doi.org/10.1117/12.3017171

KEYWORDS: Proteins, Water, Simulations, Chromophores, Fluorescent proteins, Fluorescence, Time correlated single photon counting, Systems modeling, Spectroscopy, Molecules

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Proceedings Article | 20 June 2024 Presentation

Optical ultrasound field mapping using camera-based parallelized detection

Jan Sievers, Claus Villringer, Werner Lebek, Taravat Gilani, Jan Laufer

Proceedings Volume PC13006, PC130060G (2024) https://doi.org/10.1117/12.3016764

KEYWORDS: Cameras, Ultrasonography, Sensors, Acoustics, Raster graphics, Microchannel plates, Collimation, Tunable lasers, Tissues, Tissue optics

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Proceedings Article | 11 August 2023 Paper

Plano-concave optical sensor for transcranial photoacoustic measurements

Thomas Kirchner, Claus Villringer, Marko Gutke, Jan Laufer

Proceedings Volume 12631, 126310R (2023) https://doi.org/10.1117/12.2675593

KEYWORDS: Sensors, Optical resonators, Skull, Photoacoustic spectroscopy, Bone, Acoustics, Signal attenuation, Transducers, Optical sensors, Ferroelectric materials

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Proceedings Article | 11 August 2023 Paper

Evaluation of fabrication methods for Fabry-Perot polymer film ultrasound sensors

Werner Lebek, Frank Heyroth, Frank Syrowatka, Claus Villringer, Sylvia Goerlitz, Jan Laufer

Proceedings Volume 12631, 126310Y (2023) https://doi.org/10.1117/12.2675592

KEYWORDS: Sensors, Ultrasonography, Polymers, Fabry–Perot interferometers, Polymeric sensors, Polymer thin films, Fabrication, Acoustics, Refractive index, Inhomogeneities

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Proceedings Article | 11 August 2023 Paper

Photoacoustic tomography using a Fabry-Perot sensor with homogeneous optical thickness and wide-field camera-based detection

Jan Sievers, Claus Villringer, Werner Lebek, Taravat Gilani, Jan Laufer

Proceedings Volume 12631, 126310P (2023) https://doi.org/10.1117/12.2675590

KEYWORDS: Sensors, Cameras, Photoacoustic tomography, Fabry–Perot interferometers, Raster graphics, Ultraviolet radiation, Tissues, Tissue optics, Spatial resolution, Reflection

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Proceedings Article | 11 August 2023 Paper

Difference imaging of red fluorescent proteins using pump-probe excitation

Farzin Ghane Golmohamadi, Hoang Trong Phan, Amna Mehmood, Franz-Josef Schmitt, Jan Laufer

Proceedings Volume 12631, 126310J (2023) https://doi.org/10.1117/12.2675672

KEYWORDS: Fluorescent proteins, Signal detection, Tissues, Proteins, Absorption, Tomography, Pulse signals, Photoacoustic spectroscopy, Photoacoustic imaging, Multiplexing

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Proceedings Article | 9 March 2023 Presentation

Fabry-Perot sensors with homogeneous spacer thickness for parallelized detection using a camera-based tomograph

Jan Sievers, Werner Lebek, Claus Villringer, Jan Laufer

Proceedings Volume PC12379, PC123791R (2023) https://doi.org/10.1117/12.2649123

KEYWORDS: Sensors, Cameras, Fabry–Perot interferometers, Acoustics, Raster graphics, Mirrors, Ultraviolet radiation, Transducers, Spatial resolution, Reflectivity

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Proceedings Article | 9 March 2023 Presentation

Single-chain nanoparticles as contrast agents for photoacoustic pump-probe imaging

Guo Tang, Justus Friedrich Thuemmler, Farzin Golmohamadi, Franz-Josef Schmitt, Wolfgang Binder, Jan Laufer

Proceedings Volume PC12379, PC123790Q (2023) https://doi.org/10.1117/12.2649972

KEYWORDS: Photoacoustic spectroscopy, Photoacoustic imaging, Signal attenuation, Blood, Absorption, Tomography, Spectroscopy, Signal generators, Oxygen, Modulation

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Proceedings Article | 9 March 2023 Presentation

Photoacoustic signal propagation through human cranial bones

Thomas Kirchner, Jan Laufer

Proceedings Volume PC12379, PC123791K (2023) https://doi.org/10.1117/12.2650513

KEYWORDS: Photoacoustic spectroscopy, Bone, Skull, Acoustics, Sensors, Tissue optics, Photoacoustic imaging, Transducers, Ultrasonography, Ultrasonics

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Proceedings Article | 7 March 2023 Presentation + Paper

Depth and structure information in fluorescence molecular tomography obtained from time resolved spectroscopy

J. Reisdorf, J. Laufer, F.-J. Schmitt

Proceedings Volume 12377, 123770D (2023) https://doi.org/10.1117/12.2649195

KEYWORDS: Fluorescence, Photons, Fluorescence tomography, Molecules, Time resolved spectroscopy, Signal generators, Fluorophores, Tissues, Molecular spectroscopy, Picosecond phenomena

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Proceedings Article | 9 December 2021 Paper

Pump-probe photoacoustic spectroscopy of red fluorescent proteins

Farzin Ghane Golmohamadi, Amna Mehmood, Franz-Josef Schmitt, Jan Laufer

Proceedings Volume 11923, 119230F (2021) https://doi.org/10.1117/12.2615881

KEYWORDS: Absorption, Fluorescent proteins, Spectroscopy, Photoacoustic spectroscopy, Luminescence, Signal detection, Time resolved spectroscopy, Proteins, Chromophores, Optical parametric oscillators

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SPIE Journal Paper | 6 June 2019 Open Access

Three-dimensional quantitative photoacoustic tomography using an adjoint radiance Monte Carlo model and gradient descent

Jens Buchmann, Bernhard Kaplan, Samuel Powell, Steffen Prohaska, Jan Laufer

JBO, Vol. 24, Issue 06, 066001, (June 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.6.066001

KEYWORDS: Chromophores, 3D modeling, Spherical lenses, Absorption, Photoacoustic tomography, Scattering, Monte Carlo methods, Blood, Data modeling, Photons

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Proceedings Article | 8 March 2019 Paper

Development of tuneable Fabry-Pérot sensors for parallelised photoacoustic signal acquisition

Claus Villringer, Taravat Gilani, Edward Zhang, Silvio Pulwer, Patrick Steglich, Sigurd Schrader, Jan Laufer

Proceedings Volume 10878, 108780M (2019) https://doi.org/10.1117/12.2509437

KEYWORDS: Sensors, Polymers, Refractive index, Chromophores, Electrodes, Photoacoustic spectroscopy, Cameras, Photorefractive polymers, Homogenization, Active optics

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Proceedings Article | 6 March 2019 Paper

Development of a backward-mode photoacoustic microscope using a Fabry-Pérot sensor

Ulrike Pohle, Elisabeth Baumann, Silvio Pulwer, Claus Villringer, Edward Zhang, Holger Gerhardt, Jan Laufer

Proceedings Volume 10878, 108786L (2019) https://doi.org/10.1117/12.2525785

KEYWORDS: Sensors, In vivo imaging, Photoacoustic microscopy, Microscopes, Fabry–Perot interferometers, Photoacoustic spectroscopy, Interferometers

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Proceedings Article | 4 March 2019 Presentation

Quantitative inversion of 3D multiwavelength photoacoustic images using an adjoint radiance Monte Carlo model (Conference Presentation)

Jens Buchmann, Bernhard Kaplan, Samuel Powell, Steffen Prohaska, Jan Laufer

Proceedings Volume 10878, 108781J (2019) https://doi.org/10.1117/12.2509797

KEYWORDS: 3D modeling, 3D image processing, Photoacoustic spectroscopy, Chromophores, Monte Carlo methods, Scattering, Light scattering, Calibration, Photoacoustic tomography, Tomography

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Proceedings Article | 27 February 2019 Paper

Towards biochemical sensing with gold nanoparticles through suppression of nonlinear photoacoustic signal generation

Genny Pang, Li Qiu, Christoph Haisch, Jan Laufer

Proceedings Volume 10878, 108786Q (2019) https://doi.org/10.1117/12.2523417

KEYWORDS: Coating, Nonlinear optics, Nanoparticles, Gold, Signal generators, Absorption, Tomography, Sensors, Biosensing, Photoacoustic spectroscopy

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Proceedings Article | 15 March 2018 Presentation

Development of tunable Fabry-Pérot polymer film sensors for parellelised photoacoustic signal acquisition (Conference Presentation)

Claus Villringer, Taravat Saeb Gilani, Sara Gehauf, Clemens Wiedenhöft, Patrick Steglich, Silvio Pulwer, Maria Richetta, Sigurd Schrader, Jan Laufer

Proceedings Volume 10494, 1049421 (2018) https://doi.org/10.1117/12.2290409

KEYWORDS: Sensors, Polymers, Polymer thin films, 3D acquisition, Ferroelectric polymers, Polymeric sensors, Photoacoustic spectroscopy, Acoustics, 3D image processing, Cameras

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Proceedings Article | 20 February 2018 Paper

Parallelised photoacoustic signal acquisition using a Fabry-Perot sensor and a camera-based interrogation scheme

T. Saeb Gilani, C. Villringer, E. Zhang, H. Gundlach, J. Buchmann, S. Schrader, J. Laufer

Proceedings Volume 10494, 1049431 (2018) https://doi.org/10.1117/12.2290223

KEYWORDS: Sensors, Cameras, Signal detection, Signal to noise ratio, Acoustics, Imaging systems, Fabry–Perot interferometers, Photodiodes

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SPIE Journal Paper | 17 July 2017 Open Access

Photoacoustic imaging using genetically encoded reporters: a review

Joanna Brunker, Junjie Yao, Jan Laufer, Sarah Bohndiek

JBO, Vol. 22, Issue 07, 070901, (July 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.7.070901

KEYWORDS: Photoacoustic imaging, Chromophores, Proteins, Visualization, Signal detection, Biological detection systems

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Proceedings Article | 23 March 2017 Paper

Monte-Carlo-based inversion scheme for 3D quantitative photoacoustic tomography

Bernhard Kaplan, Jens Buchmann, Steffen Prohaska, Jan Laufer

Proceedings Volume 10064, 100645J (2017) https://doi.org/10.1117/12.2251945

KEYWORDS: Modeling and simulation, Photoacoustic imaging, Blood oxygen saturation, Computational modeling, 3D modeling, Photoacoustic tomography, Model-based design, Data modeling, 3D image processing, Chromophores, Monte Carlo methods, Signal processing, Blood, Acoustics, Image segmentation, Photons, Tissue optics, Tissues

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Proceedings Article | 22 March 2017 Paper

Experimental validation of a Monte-Carlo-based inversion scheme for 3D quantitative photoacoustic tomography

Jens Buchmann, Bernhard Kaplan, Steffen Prohaska, Jan Laufer

Proceedings Volume 10064, 1006416 (2017) https://doi.org/10.1117/12.2252359

KEYWORDS: 3D modeling, Sensors, Image segmentation, Tissue optics, Absorption, Acoustics, Scattering, Nickel, Photoacoustic tomography, Chromophores, Blood oxygen saturation, Fabry–Perot interferometers, Data modeling, Photoacoustic imaging, Monte Carlo methods, Inverse problem on medical image

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Proceedings Article | 15 March 2016 Paper

Motion corrected photoacoustic difference imaging of fluorescent contrast agents

Julia Märk, Asja Wagener, Sarah Pönick, Carsten Grötzinger, Edward Zhang, Jan Laufer

Proceedings Volume 9708, 970821 (2016) https://doi.org/10.1117/12.2207302

KEYWORDS: Tissues, Molecular imaging, In vivo imaging, Photoacoustic spectroscopy, Photoacoustic imaging, Modulation, Chromophores, Proteins, Absorption, Luminescence, Visualization, Image acquisition, Signal generators

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Proceedings Article | 15 March 2016 Paper

Evaluation of Fabry-Perot polymer film sensors made using hard dielectric mirror deposition

Jens Buchmann, Edward Zhang, Chris Scharfenorth, Bastian Spannekrebs, Claus Villringer, Jan Laufer

Proceedings Volume 9708, 970856 (2016) https://doi.org/10.1117/12.2234698

KEYWORDS: Sensors, Polymers, Polymeric sensors, Acoustics, Fabry–Perot interferometers, Dielectrics, Polymer thin films, Dielectric mirrors, Photoacoustic imaging, Interferometers, Mirrors

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Proceedings Article | 15 March 2016 Paper

Dual-wavelength photoacoustic imaging of a photoswitchable reporter protein

Hakan Dortay, Julia Märk, Asja Wagener, Edward Zhang, Carsten Grötzinger, Peter Hildebrandt, Thomas Friedrich, Jan Laufer

Proceedings Volume 9708, 970820 (2016) https://doi.org/10.1117/12.2208259

KEYWORDS: Proteins, Molecular imaging, Photoacoustic imaging, In vivo imaging, Absorption, Chromophores, Sensors, Tissue optics

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Proceedings Article | 11 March 2015 Paper

Experimental validation of a theoretical model of dual wavelength photoacoustic (PA) excitation in fluorophores

Julia Märk, Christoph Theiss, Franz-Josef Schmitt, Jan Laufer

Proceedings Volume 9323, 93233G (2015) https://doi.org/10.1117/12.2082613

KEYWORDS: Absorption, Data modeling, Signal generators, Modulation, Molecules, Photons, Luminescence, Chromophores, Tissue optics, Neodymium

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Proceedings Article | 3 March 2014 Paper

Development of tyrosinase-based reporter genes for preclinical photoacoustic imaging of mesenchymal stem cells

Julia Märk, Karen Ruschke, Hakan Dortay, Isabelle Schreiber, Andrea Sass, Taimoor Qazi, Matthias Pumberger, Jan Laufer

Proceedings Volume 8943, 89433Z (2014) https://doi.org/10.1117/12.2039260

KEYWORDS: Stem cells, Photoacoustic imaging, Photoacoustic spectroscopy, Tissues, Animal model studies, Tissue optics, Sensors, Genetics, Fluorescent proteins, In vivo imaging

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Proceedings Article | 3 March 2014 Paper

Photoacoustic imaging of a near-infrared fluorescent marker based on dual wavelength pump-probe excitation

Julia Märk, Christoph Theiss, Franz-Josef Schmitt, Jan Laufer

Proceedings Volume 8943, 894333 (2014) https://doi.org/10.1117/12.2039467

KEYWORDS: Photoacoustic spectroscopy, Absorption, Tissues, Photons, Molecules, Photoacoustic imaging, 3D image processing, Signal generators, Fluorescent markers, In vivo imaging

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Proceedings Article | 3 March 2014 Paper

Photoacoustic tomography of vascular therapy in a preclinical mouse model of colorectal carcinoma

S. Johnson, O. Ogunlade, E. Zhang, J. Laufer, V. Rajkumar, R. Pedley, P. Beard

Proceedings Volume 8943, 89431R (2014) https://doi.org/10.1117/12.2039843

KEYWORDS: Acquisition tracking and pointing, Cancer, Photoacoustic tomography, Mouse models, Tumor growth modeling, In vivo imaging, Blood vessels, Tissue optics, Sensors, Tissues

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Proceedings Article | 14 June 2013 Paper

Photoacoustic tomography assessment of vascular targeted therapy to determine vessel regrowth following treatment

S. Johnson, O. Ogunlade, E. Zhang, J. Laufer, V. Rajkumar, S. Walker-Samuel, M. Lythgoe, R. Pedley, P. Beard P.

Proceedings Volume 8800, 880008 (2013) https://doi.org/10.1117/12.2033417

KEYWORDS: Acquisition tracking and pointing, Photoacoustic tomography, Photoacoustic spectroscopy, Tissue optics, Blood vessels, Skin, Tumor growth modeling, Solids, Tissues, Biomedical optics

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Proceedings Article | 4 March 2013 Paper

Vessel filtering of photoacoustic images

Tanmayi Oruganti, Jan Laufer, Bradley Treeby

Proceedings Volume 8581, 85811W (2013) https://doi.org/10.1117/12.2005988

KEYWORDS: Photoacoustic spectroscopy, Image filtering, Image segmentation, 3D image processing, Signal to noise ratio, Convolution, Algorithm development, Interference (communication), Blood, Image analysis

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Proceedings Article | 4 March 2013 Paper

Evaluation of genetically expressed absorbing proteins using photoacoustic spectroscopy

Jan Laufer, Amit Jathoul, Martin Pule, Paul Beard

Proceedings Volume 8581, 85810X (2013) https://doi.org/10.1117/12.2002497

KEYWORDS: Photoacoustic spectroscopy, Fluorescent proteins, Absorption, Proteins, Mass attenuation coefficient, Signal attenuation, Signal generators, Organisms, Photoacoustic imaging, Molecules

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SPIE Journal Paper | 1 June 2012 Open Access

Quantitative spectroscopic photoacoustic imaging: a review

Benjamin Cox, Jan Laufer, Paul Beard, Simon Arridge

JBO, Vol. 17, Issue 6, 061202, (June 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.6.061202

KEYWORDS: Absorption, Scattering, Chromophores, Acoustics, Photoacoustic spectroscopy, Tissue optics, Photoacoustic imaging, Sensors, Spectroscopy, Imaging spectroscopy

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SPIE Journal Paper | 21 May 2012 Open Access

In vivo preclinical photoacoustic imaging of tumor vasculature development and therapy

Jan Laufer, Edward Zhang, Bradley Treeby, Benjamin Cox, Paul Beard, Peter Johnson, Barbara Pedley

JBO, Vol. 17, Issue 5, 056016, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.5.056016

KEYWORDS: Tumors, Photoacoustic spectroscopy, Photoacoustic imaging, In vivo imaging, Sensors, Acoustics, Tissues, Blood vessels, 3D image processing, Image restoration

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SPIE Journal Paper | 18 May 2012 Open Access

In vivo photoacoustic imaging of mouse embryos

Jan Laufer, Francesca Norris, Jon Cleary, Edward Zhang, Bradley Treeby, Ben Cox, Sean Peter Johnson, Pete Scambler, Mark Lythgoe, Paul Beard

JBO, Vol. 17, Issue 06, 061220, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.6.061220

KEYWORDS: In vivo imaging, Photoacoustic imaging, Veins, Photoacoustic spectroscopy, Sensors, Visualization, 3D image processing, Heart, Blood vessels, Skin

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Proceedings Article | 23 February 2012 Paper

In vivo photoacoustic imaging of tyrosinase expressing tumours in mice

Jan Laufer, Amit Jathoul, Peter Johnson, Edward Zhang, Mark Lythgoe, R. Barbara Pedley, Martin Pule, Paul Beard

Proceedings Volume 8223, 82230M (2012) https://doi.org/10.1117/12.907006

KEYWORDS: Photoacoustic imaging, Photoacoustic spectroscopy, Absorption, Sensors, Tissues, In vivo imaging, Skin, 3D image processing, Genetics, Imaging systems

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SPIE Journal Paper | 1 September 2011 Open Access

Automatic sound speed selection in photoacoustic image reconstruction using an autofocus approach

Bradley Treeby, Trond Varslot, Edward Zhang, Jan Laufer, Paul Beard

JBO, Vol. 16, Issue 09, 090501, (September 2011) https://doi.org/10.1117/12.10.1117/1.3619139

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Proceedings Article | 1 March 2011 Paper

Use of a pulsed fibre laser as an excitation source for photoacoustic tomography

Thomas Allen, Shaiful Alam, Edward Zhang, Jan Laufer, David Richardson, Paul Beard

Proceedings Volume 7899, 78991V (2011) https://doi.org/10.1117/12.875291

KEYWORDS: Fiber lasers, Photoacoustic spectroscopy, Photoacoustic tomography, Signal detection, Pulsed fiber lasers, Tissue optics, Laser tissue interaction, Photoacoustic imaging, Imaging systems, Tissues

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Proceedings Article | 28 February 2011 Paper

In vivo longitudinal photoacoustic imaging of subcutaneous tumours in mice

Jan Laufer, Peter Johnson, Edward Zhang, Bradley Treeby, Ben Cox, Barbara Pedley, Paul Beard

Proceedings Volume 7899, 789915 (2011) https://doi.org/10.1117/12.876782

KEYWORDS: Photoacoustic spectroscopy, Photoacoustic imaging, Ultrasonography, 3D image processing, Sensors, Fabry–Perot interferometers, Blood vessels, In vivo imaging, Image resolution, Imaging systems

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Proceedings Article | 23 February 2011 Paper

Acoustic attenuation compensation in photoacoustic tomography: application to high-resolution 3D imaging of vascular networks in mice

Bradley Treeby, Jan Laufer, Edward Zhang, Francesca Norris, Mark Lythgoe, Paul Beard, B. Cox

Proceedings Volume 7899, 78992Y (2011) https://doi.org/10.1117/12.874530

KEYWORDS: Signal attenuation, Acoustics, Sensors, Photoacoustic spectroscopy, Absorption, Photoacoustic tomography, Tissues, Reconstruction algorithms, Inverse problems, Tissue optics

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Proceedings Article | 16 February 2011 Paper

Multimodal optical coherence/photoacoustic tomography of skin

Aneesh Alex, Edward Zhang, Boris Považay, Jan Laufer, Bernd Hofer, Carl Glittenberg, Boris Hermann, Paul Beard, Wolfgang Drexler

Proceedings Volume 7889, 788916 (2011) https://doi.org/10.1117/12.875499

KEYWORDS: Optical coherence tomography, Skin, Acquisition tracking and pointing, Imaging systems, Sensors, Tissue optics, In vivo imaging, Tissues, Tomography, Multimodal imaging

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Proceedings Article | 24 February 2010 Paper

Multimodal simultaneous photoacoustic tomography, optical resolution microscopy, and OCT system

Edward Zhang, Jan Laufer, Boris Považay, Aneesh Alex, Bernd Hofer, Wolfgang Drexler, Paul Beard

Proceedings Volume 7564, 75640U (2010) https://doi.org/10.1117/12.841615

KEYWORDS: Acquisition tracking and pointing, Optical coherence tomography, Sensors, Tissues, Ultrasonography, Acoustics, Signal detection, Photoacoustic spectroscopy, Spatial resolution, Photoacoustic tomography

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Proceedings Article | 24 February 2010 Paper

Photoacoustic imaging of vascular networks in transgenic mice

J. Laufer, J. Cleary, E. Zhang, M. Lythgoe, P. Beard

Proceedings Volume 7564, 75641A (2010) https://doi.org/10.1117/12.842204

KEYWORDS: Photoacoustic spectroscopy, Chromophores, Photoacoustic imaging, Tissue optics, Blood, Genetics, Absorption, Visualization, Heart, 3D image processing

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Proceedings Article | 27 February 2009 Paper

The challenges for quantitative photoacoustic imaging

B. Cox, J. Laufer, P. Beard

Proceedings Volume 7177, 717713 (2009) https://doi.org/10.1117/12.806788

KEYWORDS: Tissue optics, Photoacoustic spectroscopy, Absorption, Photoacoustic imaging, Chromophores, Inverse optics, Acoustics, Tissues, Scattering, Inverse problems

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Proceedings Article | 28 February 2008 Paper

3D photoacoustic imaging system for in vivo studies of small animal models

Edward Zhang, Jan Laufer, R. Barbara Pedley, Paul Beard

Proceedings Volume 6856, 68560P (2008) https://doi.org/10.1117/12.763086

KEYWORDS: Sensors, Imaging systems, 3D image reconstruction, 3D image processing, 3D modeling, In vivo imaging, Signal detection, Photoacoustic spectroscopy, Photoacoustic imaging, Data acquisition

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Proceedings Article | 28 February 2008 Paper

Quantitative imaging of chromophore concentrations using a photoacoustic forward model

J. Laufer, E. Zhang, B. Cox, P. Beard

Proceedings Volume 6856, 68560Z (2008) https://doi.org/10.1117/12.764558

KEYWORDS: Photoacoustic spectroscopy, Chromophores, Absorption, Tissue optics, Model-based design, Data modeling, Acoustics, Reconstruction algorithms, Scattering, Tissues

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Proceedings Article | 13 February 2007 Paper

Three-dimensional photoacoustic imaging of vascular anatomy in small animals using an optical detection system

Edward Zhang, Jan Laufer, Paul Beard

Proceedings Volume 6437, 64370S (2007) https://doi.org/10.1117/12.700128

KEYWORDS: Sensors, Imaging systems, Photoacoustic spectroscopy, 3D image processing, 3D image reconstruction, Photoacoustic imaging, Tissues, Ultrasonography, Acoustics, Optical parametric oscillators

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Proceedings Article | 13 February 2007 Paper

Quantitative in-vivo measurements of blood oxygen saturation using multiwavelength photoacoustic imaging

J. Laufer, E. Zhang, P. Beard

Proceedings Volume 6437, 64371Z (2007) https://doi.org/10.1117/12.700297

KEYWORDS: Photoacoustic spectroscopy, Chromophores, Absorption, Blood, Tissue optics, Blood vessels, Scattering, In vivo imaging, Photoacoustic imaging, Finite element methods

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Proceedings Article | 6 March 2006 Paper

Absolute measurements of local chromophore concentrations using pulsed photoacoustic spectroscopy

J. Laufer, C. Elwell, D. Delpy, P. Beard

Proceedings Volume 6086, 60861J (2006) https://doi.org/10.1117/12.657372

KEYWORDS: Photoacoustic spectroscopy, Capillaries, Blood, Chromophores, Tissues, Absorption, Signal detection, Ultrasonography, Scattering, Tissue optics

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Proceedings Article | 12 July 2004 Paper

Experimental validation of photoacoustic k-Space propagation models

Benjamin Cox, Jan Laufer, Kornel Kostli, Paul Beard

Proceedings Volume 5320, (2004) https://doi.org/10.1117/12.531178

KEYWORDS: Sensors, 3D modeling, Pulsed laser operation, Solids, Photoacoustic spectroscopy, Wave propagation, Radio propagation, Photoacoustic imaging, Acoustics, Absorption

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Proceedings Article | 12 July 2004 Paper

Pulsed near-infrared photoacoustic spectroscopy of blood

Jan Laufer, Clare Elwell, Dave Delpy, Paul Beard

Proceedings Volume 5320, (2004) https://doi.org/10.1117/12.531159

KEYWORDS: Blood, Photoacoustic spectroscopy, Scattering, Absorption, Signal detection, Oxygen, Mie scattering, Signal attenuation, Optical parametric oscillators, Light scattering

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Proceedings Article | 29 June 2001 Paper

Near-infrared optical coefficients of tumors and adjacent normal tissue

Jan Laufer

Proceedings Volume 4250, (2001) https://doi.org/10.1117/12.434537

KEYWORDS: Tissues, Tissue optics, Absorption, Scattering, Liver, Transmittance, Reflectivity, Breast, Kidney, Monte Carlo methods

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Proceedings Article | 21 April 1999 Paper

Photoacoustic/photothermal optical fiber sensor for the minimally invasive detection of cancers and other tissue pathologies

Jan Laufer, Paul Beard, Timothy Mills

Proceedings Volume 3596, (1999) https://doi.org/10.1117/12.346717

KEYWORDS: Tissue optics, Sensors, Optical fibers, Finite element methods, Scattering, Absorption, Signal detection, Tissues, Polymer thin films, Polymers

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Proceedings Article | 18 August 1997 Paper

Near-infrared optical properties of ex-vivo human skin and subcutaneous tissues using reflectance and transmittance measurements

Rebecca Simpson, Jan Laufer, Matthias Kohl-Bareis, Matthias Essenpreis, Mark Cope

Proceedings Volume 2979, (1997) https://doi.org/10.1117/12.280259

KEYWORDS: Tissues, Optical properties, Reflectivity, Absorption, Scattering, Transmittance, Skin, Monte Carlo methods, Light scattering, Integrating spheres

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