Dr. Joseph Chue-Sang Profile

Dr. Joseph Chue-Sang

Physicist Sr. at SAIC

SPIE Involvement:

Author

Publications (23)

Proceedings Article | 15 March 2023 Presentation

Combining Mueller matrix imaging with spatial frequency domain imaging (Conference Presentation)

Thomas Germer, Joseph Chue-Sang

Proceedings Volume PC12382, PC123820F (2023) https://doi.org/10.1117/12.2655702

KEYWORDS: Tissue optics, Spatial frequencies, Optical alignment, Mueller matrices, Biomedical optics

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SPIE Journal Paper | 14 December 2022 Open Access

Spatial frequency domain Mueller matrix imaging

Joseph Chue-Sang, Maritoni Litorja, Aaron Goldfain, Thomas A. Germer

JBO, Vol. 27, Issue 12, 126003, (December 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.12.126003

KEYWORDS: Mueller matrices, Spatial frequencies, Bidirectional reflectance transmission function, Scattering, White matter, Polydimethylsiloxane, Biomedical optics, Polarization, Thalamus, Polarimetry

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Proceedings Article | 7 March 2022 Presentation

Imaging of media with spatial frequency domain Mueller matrix imaging

Joseph Chue-Sang, Thomas Germer

Proceedings Volume PC11963, PC1196304 (2022) https://doi.org/10.1117/12.2615353

KEYWORDS: Tissues, Polarimetry, Scattering, Multilayers, Light sources, Collagen, Cancer, Anisotropy

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Proceedings Article | 1 April 2021 Presentation + Paper

Spatial frequency domain Mueller matrix imaging

Joseph Chue-Sang, Aaron Goldfain, Jeeseong Hwang, Thomas Germer

Proceedings Volume 11646, 116460E (2021) https://doi.org/10.1117/12.2576350

KEYWORDS: Polarimetry, Wave plates, Polarization, Multilayers, Modulation, Liquid crystals, Light sources, Condition numbers, Calibration, Biomedical optics

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Proceedings Article | 20 August 2020 Presentation

Spatial frequency domain Mueller matrix imaging to distinguish between birefringent materials in depth

Joseph Chue-Sang, Thomas Germer

Proceedings Volume 11485, 114850F (2020) https://doi.org/10.1117/12.2568553

KEYWORDS: Polarimetry, Wave plates, Anisotropy, Multilayers, Light sources, Liquid crystals, Modulation, Polarization, Calibration, Condition numbers

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SPIE Journal Paper | 8 March 2019 Open Access

Optical phantoms for biomedical polarimetry: a review

Joseph Chue-Sang, Mariacarla Gonzalez, Angie Pierre, Megan Laughrey, Ilyas Saytashev, Tatiana Novikova, Jessica C. Ramella-Roman

JBO, Vol. 24, Issue 03, 030901, (March 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.3.030901

KEYWORDS: Polarimetry, Tissues, Polarization, Birefringence, Biomedical optics, Optical phantoms, Tissue optics, Collagen, Scattering, Polymers

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Calibration, quantification, and standardization of the polarimetric instrumentation, as well as interpretation and understanding of the obtained data, require the development and use of well-calibrated phantoms and standards. We reviewed the status of tissue phantoms for a variety of applications in polarimetry; more than 500 papers are considered. We divided the phantoms into five groups according to their origin (biological/nonbiological) and fundamental polarimetric properties of retardation, depolarization, and diattenuation. We found that, while biological media are generally depolarizing, retarding, and diattenuating, only one of all the phantoms reviewed incorporated all these properties, and few considered at least combined retardation and depolarization. Samples derived from biological tissue, such as tendon and muscle, remain extremely popular to quickly ascertain a polarimetric system, but do not provide quantifiable results aside from relative direction of their principal optical axis. Microspheres suspensions are the most utilized phantoms for depolarization, and combined with theoretical models can offer true quantification of depolarization or degree of polarization. There is a real paucity of birefringent phantoms despite the retardance being one of the most interesting parameters measurable with polarization techniques. Therefore, future work should be directed at generating truly reliable and repeatable phantoms for this metric determination. Diattenuating phantoms are rare and application-specific. Given that diattenuation is considered to be low in most biological tissues, the lack of such phantoms is seen as less problematic. The heterogeneity of the phantoms reviewed points to a critical need for standardization in this field. Ultimately, all research groups involved in polarimetric studies and instruments development would benefit from sharing a limited set of standardized polarimetric phantoms, as is done earlier in the round robin investigations in ellipsometry.

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Proceedings Article | 4 March 2019 Presentation

Polarized light Monte Carlo simulation of cervical collagen ultrastructure (Conference Presentation)

Joseph Chue-Sang, Jessica Ramella-Roman

Proceedings Volume 10876, 108760P (2019) https://doi.org/10.1117/12.2508611

KEYWORDS: Collagen, Monte Carlo methods, Cervix, Polarimetry, Polarized microscopy, Microscopy, In vivo imaging, Signal attenuation, Light scattering, Scattering

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SPIE Journal Paper | 7 August 2018 Open Access

Use of Mueller matrix colposcopy in the characterization of cervical collagen anisotropy

Joseph Chue-Sang, Nola Holness, Mariacarla Gonzalez, Joan Greaves, Ilyas Saytashev, Susan Stoff, Amir Gandjbakhche, Viktor Chernomordik, Gene Burkett, Jessica Ramella-Roman

JBO, Vol. 23, Issue 12, 121605, (August 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.12.121605

KEYWORDS: Cervix, Collagen, Anisotropy, In vivo imaging, Polarimetry, Polarization, Wave plates, Statistical analysis, Diagnostics, Birefringence

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Proceedings Article | 5 April 2018 Presentation + Paper

Development and characterization of a snapshot Mueller matrix polarimeter for the determination of cervical cancer risk in the low resource setting

Jessica Ramella-Roman, Mariacarla Gonzalez, Joseph Chue-Sang , Karla Montejo, Karl Krup, Vijaya Srinivas, Edward DeHoog, Purnima Madhivanan

Proceedings Volume 10485, 104850X (2018) https://doi.org/10.1117/12.2290592

KEYWORDS: Polarimetry, Cervical cancer, Cervix, Collagen, Polarization, Light emitting diodes, Imaging systems, Diagnostics, Brain-machine interfaces, Optical coherence tomography

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Proceedings Article | 14 March 2018 Presentation

Comparison of collagen orientation and distribution in-vivo between non-pregnant and pregnant human cervix using Mueller Matrix polarimetry (Conference Presentation)

Joseph Chue-Sang, Mariacarla Gonzalez, Nola Holness, Ilyas Saytashev, Amir Gandjbakhche, Victor Chernomordik, Jessica Ramella-Roman

Proceedings Volume 10472, 1047205 (2018) https://doi.org/10.1117/12.2290595

KEYWORDS: Collagen, In vivo imaging, Cervix, Polarimetry, Ranging, Polarization, Optical testing, Anisotropy, Stars

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Proceedings Article | 2 March 2018 Presentation + Paper

Optimization of the incident wavelength in Mueller matrix imaging of cervical collagen

Joseph Chue-Sang, Jessica Ramella-Roman

Proceedings Volume 10478, 1047809 (2018) https://doi.org/10.1117/12.2290766

KEYWORDS: Collagen, Cervix, Polarimetry, Wave plates, Polymers, Linear polarizers, Anisotropy, Tissues, Scattering, Imaging systems

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SPIE Journal Paper | 26 October 2017 Open Access

Use of combined polarization-sensitive optical coherence tomography and Mueller matrix imaging for the polarimetric characterization of excised biological tissue (Erratum)

Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, David Straton, Sharan Ramaswamy, Jessica Ramella-Romana

JBO, Vol. 22, Issue 10, 109801, (October 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.10.109801

KEYWORDS: Polarimetry, Optical coherence tomography, Tissue optics, Biomedical engineering, Medicine

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SPIE Journal Paper | 29 August 2017 Open Access

Use of Mueller matrix polarimetry and optical coherence tomography in the characterization of cervical collagen anisotropy

Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, Mariacarla Gonzalez, Nola Holness, Jefferson Gomes, Ranu Jung, Amir Gandjbakhche, Viktor Chernomordik, Jessica Ramella-Roman

JBO, Vol. 22, Issue 08, 086010, (August 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.8.086010

KEYWORDS: Collagen, Cervix, Optical coherence tomography, Polarimetry, Anisotropy, Silicon, Tissues, Optical fibers, Polarization, Uterus

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Proceedings Article | 19 April 2017 Presentation

Handheld SFDI/polarimetric imaging device for objective evaluation of hypertrophic scars (Conference Presentation)

Jessica Ramella-Roman, Karla Montejo, Nicole Sevilla, Susan Stoff, Mariacarla Gonzalez, Joseph Chue-Sang

Proceedings Volume 10049, 1004905 (2017) https://doi.org/10.1117/12.2251001

KEYWORDS: Polarimetry, Light emitting diodes, Tissues, Imaging devices, Diagnostics, Imaging systems, Fiber optic illuminators, System integration, Collagen, Surgery

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Proceedings Article | 2 March 2017 Paper

Quantitative analysis of a scar's pliability, perfusion and metrology

Mariacarla Gonzalez, Nicole Sevilla, Joseph Chue-Sang, Jessica Ramella-Roman

Proceedings Volume 10067, 100670R (2017) https://doi.org/10.1117/12.2252676

KEYWORDS: Skin, Metrology, Quantitative analysis, Tissues, Visualization, Diagnostics, Laser speckle imaging, Speckle, Injuries, Speckle pattern

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Proceedings Article | 2 March 2017 Paper

Use of Mueller matrix polarimetry and optical coherence tomography in the characterization of cervical collagen anisotropy

Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, Mariacarla Gonzalez, Jefferson Gomes, Amir Gandjbakhche, Viktor Chernomordik, Jessica Ramella-Roman

Proceedings Volume 10043, 100430U (2017) https://doi.org/10.1117/12.2250969

KEYWORDS: Collagen, Polarimetry, Cervix, Second-harmonic generation, Polarization, Anisotropy, Optical coherence tomography, Silicon, Tissues, Birefringence

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Proceedings Article | 2 March 2017 Presentation + Paper

Use of Mueller matrix colposcopy in the characterization of cervical collagen anisotropy

Karla Montejo, Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, Nola Holness, Mariacarla Gonzalez, Jefferson Gomes, Amir Gandjbakhche, Viktor Chernomordik, Jessica Ramella-Roman

Proceedings Volume 10043, 1004303 (2017) https://doi.org/10.1117/12.2250987

KEYWORDS: Collagen, Polarimetry, In vivo imaging, Cervix, Anisotropy, Polarization, Optical coherence tomography, Biomedical optics, Tissue optics, Tissues

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Proceedings Article | 27 April 2016 Presentation

Polarized light in birefringent samples (Conference Presentation)

Joseph Chue-Sang, Yuqiang Bai, Jessica Ramella-Roman

Proceedings Volume 9689, 96890A (2016) https://doi.org/10.1117/12.2213335

KEYWORDS: Tissue optics, Monte Carlo methods, Tissues, Polarization, Collagen, Cervix, Connective tissue, Diseases and disorders, Sensors, Birefringence

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Proceedings Article | 27 April 2016 Presentation

Imaging of skin surface architecture with out of plane polarimetry (Conference Presentation)

Joseph Chue-Sang, Jessica Ramella-Roman

Proceedings Volume 9689, 96890C (2016) https://doi.org/10.1117/12.2213365

KEYWORDS: Skin, Polarimetry, Imaging systems, Natural surfaces, Light sources, Tissue optics, Polarization, Diagnostics, Current controlled current source

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Proceedings Article | 26 April 2016 Presentation

Imaging and modeling of collagen architecture in living tissue with polarized light transfer (Conference Presentation)

Jessica Ramella-Roman, Susan Stoff, Joseph Chue-Sang, Yuqiang Bai

Proceedings Volume 9696, 969603 (2016) https://doi.org/10.1117/12.2213222

KEYWORDS: Collagen, Tissue optics, Connective tissue, Diagnostics, Cervical cancer, Skin cancer, Cervix, Imaging systems, Microscopy, Animal model studies

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Proceedings Article | 8 March 2016 Paper

Cervical collagen imaging for determining preterm labor risks using a colposcope with full Mueller matrix capability

Susan Stoff, Joseph Chue-Sang, Nola Holness, Amir Gandjbakhche, Viktor Chernomordik, Jessica Ramella-Roman

Proceedings Volume 9689, 968947 (2016) https://doi.org/10.1117/12.2213387

KEYWORDS: Fetus, Collagen, Polarimetry, Cervix, Analytical research, Polarization, Diagnostics, Birefringence, Reproductive system, Imaging systems, Standards development

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SPIE Journal Paper | 1 March 2016 Open Access

Use of combined polarization-sensitive optical coherence tomography and Mueller matrix imaging for the polarimetric characterization of excised biological tissue

Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, David Straton, Sharan Ramaswamy, Jessica Ramella-Roman

JBO, Vol. 21, Issue 07, 071109, (March 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.7.071109

KEYWORDS: Optical coherence tomography, Polarimetry, Birefringence, Tissue optics, Tissues, Polarization, Collagen, Imaging systems, Data modeling, Heart

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