Dr. Katarzyna Komolibus Profile

Dr. Katarzyna Komolibus

Senior Researcher at Tyndall National Institute

Publications (16)

Proceedings Article | 18 June 2024 Presentation + Paper

Explainable machine learning for the multiclass classification of diffuse reflectance spectroscopy signals in orthopaedic applications

Nicola Rossberg, Celina Li, Stefan Andersson-Engels, Barry O'Sullivan, Katarzyna Komolibus, Andrea Visentin

Proceedings Volume 13011, 130110B (2024) https://doi.org/10.1117/12.3017001

KEYWORDS: Tissues, Machine learning, Transformers, Visualization, Reflectivity, Diffuse reflectance spectroscopy, Random forests, Diffuse optical spectroscopy, Artificial intelligence, Convolutional neural networks, Orthopedic imaging

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Proceedings Article | 18 June 2024 Presentation + Paper

A comprehensive pipeline to integrate preprocessing and machine learning techniques for accurate classification in Raman spectroscopy

Simone Innocente, Siddra Maryam, Stefan Andersson-Engels, Katarzyna Komolibus, Rekha Gautam, Andrea Visentin

Proceedings Volume 13011, 1301107 (2024) https://doi.org/10.1117/12.3017024

KEYWORDS: Raman spectroscopy, Data modeling, Cross validation, Machine learning, Ovarian cancer

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Proceedings Article | 17 October 2023 Paper

A virtual comparison of different time-of-flight-based diffuse optical spectroscopic techniques

Pranav Lanka, Marcelo Saito Nogueira, Vanessa R. Rodrigues, Shree Krishnamoorthy, Katarzyna Komolibus, Rekha Gautam, Stefan Andersson-Engels, Sanathana Konugolu Venkata Sekar

Proceedings Volume 12628, 126282L (2023) https://doi.org/10.1117/12.2671008

KEYWORDS: Spectroscopy, Optical spectroscopy, Tissues, Optical properties, Matrices, Interferometry, Background noise

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SPIE Journal Paper | 5 September 2023 Open Access

Frameworks of wavelength selection in diffuse reflectance spectroscopy for tissue differentiation in orthopedic surgery

Celina Li, Carl Fisher, Katarzyna Komolibus, Konstantin Grygoryev, Huihui Lu, Ray Burke, Andrea Visentin, Stefan Andersson-Engels

JBO, Vol. 28, Issue 12, 121207, (September 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.12.121207

KEYWORDS: Bone, Tissues, Principal component analysis, Cements, Diffuse reflectance spectroscopy, Surgery, Data modeling, Education and training, Feature selection, Absorption

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Proceedings Article | 30 June 2022 Open Access

Online learning combining virtual lectures, at-home experiments and computer simulations: a multidisciplinary teaching and learning approach

Marcelo Nogueira, Katarzyna Komolibus, Jacqueline Gunther, Sanathana Konugolu, Venkata Sekar, Baptiste Jayet, Andrea Tobo, Celina Li, Siddra Maryam, Caitriona Tyndall, Stefan Andersson-Engels

Proceedings Volume 12297, 122970T (2022) https://doi.org/10.1117/12.2635530

KEYWORDS: Computer simulations, Biomedical optics, Virtual reality, Photonics, Physics, Roads, Education and training, Chemistry, Technologies and applications, Scanning transmission electron microscopy

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Proceedings Article | 30 June 2022 Open Access

Biophotonics box: educational kit for multidisciplinary outreach activities in optics and photonics

Marcelo Nogueira, Katarzyna Komolibus, Andrea Tobo, Baptiste Jayet, Sanathana Konugolu Venakata Sekar, Simon Sørensen, Caitriona Tyndall, Stefan Andersson-Engels

Proceedings Volume 12297, 122972L (2022) https://doi.org/10.1117/12.2635595

KEYWORDS: Biomedical optics, Photonics, Computer simulations, Scanning transmission electron microscopy, Medicine, Luminescence, Light scattering, Electronic components, Education and training, Biology

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Proceedings Article | 2 March 2022 Poster + Presentation + Paper

Multidisciplinary teaching and learning biophotonics: assessing the effectiveness of fully online outreach events

Marcelo Saito Nogueira, Celina Li, Siddra Maryam, Caitriona Tyndall, Sarah Donovan, Katarzyna Komolibus, Jacqueline Elizabeth Gunther, Sanathana Konugolu Venkata Sekar, Baptiste Jayet, Carl Fisher, Declan Kennedy, Stefan Andersson-Engels

Proceedings Volume 11958, 119580I (2022) https://doi.org/10.1117/12.2608138

KEYWORDS: Biomedical optics, Tissue optics, Computer simulations, Luminescence, Fluorescence spectroscopy, Spectroscopy, Raman spectroscopy, Virtual reality, Tissues, Skin, Optics education, Education and training, Biomedical optics and medical imaging, Medical devices, Medical device development

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SPIE Journal Paper | 5 January 2022 Open Access

Perspective on the integration of optical sensing into orthopedic surgical devices

Carl Fisher, James Harty, Albert J. Yee, Celina Li, Katarzyna Komolibus, Konstantin Grygoryev, Huihui Lu, Ray Burke, Brian Wilson, Stefan Andersson-Engels

JBO, Vol. 27, Issue 01, 010601, (January 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.1.010601

KEYWORDS: Surgery, Bone, Optical sensing, Tissue optics, Integrated optics, Tissues, Optical properties, Robotics, Soft tissue optics, Scattering

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SPIE Journal Paper | 23 July 2021 Open Access

Perspectives on interstitial photodynamic therapy for malignant tumors

Katarzyna Komolibus, Carl Fisher, Johannes Swartling, Sune Svanberg, Katarina Svanberg, Stefan Andersson-Engels

JBO, Vol. 26, Issue 07, 070604, (July 2021) https://doi.org/10.1117/12.10.1117/1.JBO.26.7.070604

KEYWORDS: Tumors, Photodynamic therapy, Tissues, Prostate, Solids, Therapeutics, Diffusers, Cancer, Oxygen, Brain

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Proceedings Article | 24 March 2020 Presentation + Paper

User-friendly graphical user interface for simulating tissue optical properties and fluence rates: improving students learning in tissue optics

Marcelo Saito Nogueira, Jacqueline Elizabeth Gunther, Katarzyna Komolibus, Stefan Andersson-Engels

Proceedings Volume 11238, 112380B (2020) https://doi.org/10.1117/12.2546811

KEYWORDS: Computer simulations, Tissue optics, Biomedical optics, Absorption, Tissues, Computer programming, Optical properties, Human-machine interfaces, Monte Carlo methods, Optical simulations

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Proceedings Article | 2 July 2019 Open Access

Method of continuous improvement of multidisciplinary programs and outreach activities

Marcelo S. Nogueira, Jacqueline Gunther, Katarzyna Komolibus, Sinéad M. Ryan, Brian Murray, Moises Jezzini, Declan Kennedy, Stefan Andersson-Engels

Proceedings Volume 11143, 111432C (2019) https://doi.org/10.1117/12.2523352

KEYWORDS: Biomedical optics, Photonics, Tissue optics, Oncology, Biological research, Computer simulations, Tissues, Education and training, Optics education, Engineering education, Outreach programs, Optics

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Proceedings Article | 1 March 2019 Paper

Teaching light-tissue interactions: using technology for education

Marcelo Saito Nogueira, Jacqueline Gunther, Katarzyna Komolibus, Stefan Andersson-Engels

Proceedings Volume 10876, 108761H (2019) https://doi.org/10.1117/12.2507960

KEYWORDS: Biomedical optics, Tissue optics, Computer programming, Tissues, Absorption, Optical properties, Software, Human-machine interfaces, Scattering, Computer simulations, Optics education, Education and training, Biophotonic applications

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Proceedings Article | 1 March 2019 Paper

Fluorescence spectroscopy of mouse organs using ultraviolet excitation: towards assessment of organ viability for transplantation

Marcelo Saito Nogueira, Katarzyna Komolibus, Konstantin Grygoryev, Jacqueline Gunther, Stefan Andersson-Engels

Proceedings Volume 10876, 1087606 (2019) https://doi.org/10.1117/12.2510966

KEYWORDS: Biomedical optics, Clinical research, Optical diagnostics, Luminescence, Tissues, Liver, Fluorescence spectroscopy, Ultraviolet radiation, Kidney, Lung, Transplantation, Tissue optics, Absorption

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Identifying diseases and evaluating tissue function and viability can be performed by subjective or objective methods. However, subjective techniques may be inaccurate and non-optical objective techniques may be relatively expensive and time-consuming. Then, these techniques may not be suitable for clinical applications that require immediate assessment and intervention. Fluorescence spectroscopy (FS) is one of the optical techniques with great potential for medical diagnostics and surgical guidance. This potential is associated to the possibility of label-free techniques biochemical sensitivity without contrast agents. For clinical applications, fluorescence can be used to assess biomolecular content of respiratory metabolism involving NAD(P)H and FAD. In addition, changes in collagen, elastin, porphyrin, pyridoxine, and tryptophan content can potentially be detected. One way to collect epifluorescence signals from superficial tissue layers is using ultraviolet (UV) excitation. In this study, we used UV excitation FS to investigate the effect of temperature variation (from 0 to 25 degrees Celsius) on tissue autofluorescence. The measurements reproducibility was assessed by variations of the spectral shape accounted by the calculation of the Pearson correlation coefficient for each pair of measurements. Overall, fluorescence measurements were more reproducible at 25°C compared to 0°C. Liver showed lowest fluorescence variability (most homogeneous organ) regarding results from both 300 nm and 340 nm excitations. We report temperature and wavelength-dependent spectral changes due to the tissue thawing by calculating the difference between normalized UVEFS measurements at 0°C and 25°C. Observed differences may be attributed to blood absorption and NADH fluorescence emission. Our results can be used to increase the database of tissue fluorescence spectra using UV excitation for future reference to choose targeted wavelengths in fluorescence instrumentation. Furthermore, our study illustrates expected fluorescence variations during the assessment of organs viability for transplantation, especially due to cold preservation.

Proceedings Article | 17 May 2018 Paper

Diffuse reflectance spectroscopy for determination of optical properties and chromophore concentrations of mice internal organs in the range of 350 nm to 1860 nm

Marcelo Saito Nogueira, Michael Raju, Jacqueline Gunther, Konstantin Grygoryev, Katarzyna Komolibus, Huihui Lu, Stefan Andersson-Engels

Proceedings Volume 10685, 106853G (2018) https://doi.org/10.1117/12.2306636

KEYWORDS: Tissues, Scattering, Reflectivity, Heart, Liver, Mie scattering, Kidney, Chromophores, Optical properties, Rayleigh scattering, Diffuse reflectance spectroscopy, Optical diagnostics, Biomedical optics, Biophotonic applications, Monte Carlo methods

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Proceedings Article | 4 March 2016 Paper

Influence of p-doping on the gain and refractive index dynamics in quantum dash based semiconductor optical amplifiers

Katarzyna Komolibus, Tomasz Piwonski, Siddharth Joshi, Nicolas Chimot, John Houlihan, Francois Lelarge, Guillaume Huyet

Proceedings Volume 9742, 974219 (2016) https://doi.org/10.1117/12.2212867

KEYWORDS: Carrier dynamics, Refractive index, Semiconductor optical amplifiers, Indium arsenide, Modulation, Quantum dots, Ultrafast phenomena, Picosecond phenomena, Absorption, Transparency, Spectroscopy, Heterodyning

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Proceedings Article | 27 February 2015 Paper

Complex emission dynamics from InGaAs/GaAs core-shell nanopillars

Katarzyna Komolibus, Adam Scofield, Tomasz Ochalski, Bryan Kelleher, David Goulding, Diana Huffaker, Guillaume Huyet

Proceedings Volume 9373, 93730A (2015) https://doi.org/10.1117/12.2080269

KEYWORDS: Picosecond phenomena, Indium gallium arsenide, Indium, Luminescence, Gallium arsenide, Silicon photonics, Optical properties, Scanning electron microscopy, Silicon, Interfaces

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Showing 5 of 16 publications

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