Reoperations and unnecessary removal of healthy tissue could be reduced if non-invasive imaging techniques were available for presurgical tumor delineation in skin cancer. In this study, 3D multiwavelength photoacoustic imaging was performed ex vivo on 25 melanomas and 27 nevi. The tumors were delineated using spectral unmixing at 59 excitation wavelengths, from 680 nm to 970 nm, accounting for multiple tissue chromophores. The tumor dimensions determined with photoacoustic imaging were strongly correlated with those determined by histopathological examination for both melanomas and nevi.
We present and validate a simulation package for simulating the signal generated from arbitrary acousto-optical interaction in scattering media. We further present an example on how the package can be used as a virtual lab.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.