Dr. Michael Mandella Profile

Dr. Michael Mandella

SPIE Involvement:

Author | Startup Challenge Judge

Publications (17)

SPIE Journal Paper | 9 April 2019 Open Access

Tunable structured illumination light sheet microscopy for background rejection and imaging depth in minimally processed tissues

Joseph R. Landry, Ryosuke Itoh, Jonathan M. Li, Stephen S. Hamann, Michael Mandella, Christopher H. Contag, Olav Solgaard

JBO, Vol. 24, Issue 04, 046501, (April 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.4.046501

KEYWORDS: Spatial frequencies, Microscopy, Tissues, Scattering, Prisms, Light scattering, Microscopes, Image quality, Point spread functions, Spatial light modulators

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Proceedings Article | 14 March 2018 Presentation

MEMS based multi-spectral dual-axis confocal microendoscope for clinical applications (Conference Presentation)

Zhen Qiu, Nathan Loewke, Wibool Piyawattanametha, Il-woong Jung, Tarn Teraphongphom, Robert Ertsey, Frank Schonig, Stephan Rogalla, Shai Friedland, Michael Mandella, Daniel Lopez, Eben Rosenthal, Christopher Contag

Proceedings Volume 10545, 105450N (2018) https://doi.org/10.1117/12.2292262

KEYWORDS: Microelectromechanical systems, Confocal microscopy, Cancer, Scanners, Colorectal cancer, Microopto electromechanical systems, Tumors, Imaging systems, Molecular imaging, Algorithm development

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Proceedings Article | 14 March 2018 Presentation

Handheld dual-modality wide-field fluorescent imaging guided dual-axis confocal microscope for fluorescence molecular guidance of precise tumor resection in head and neck surgery (Conference Presentation)

Zhen Qiu, Tarn Teraphongphom, Nynke van den Berg, Nathan Loewke, Guolan Lu, Robert Ertsey, Frank Schonig, Stephan Rogalla, Shai Friedland, Michael Mandella, Eben Rosenthal, Christopher Contag

Proceedings Volume 10478, 104780E (2018) https://doi.org/10.1117/12.2291986

KEYWORDS: Luminescence, Tissues, Microscopes, Tissue optics, Confocal microscopy, Tumors, Head, Neck, Imaging systems, Surgery

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Proceedings Article | 19 April 2017 Presentation

A handheld MEMS-based line-scanned dual-axis confocal microscope for early cancer detection and surgical guidance (Conference Presentation)

Ye Chen, Chengbo Yin, Linpeng Wei, Adam Glaser, Sanjee Abeytunge, Gary Peterson, Michael Mandella, Nader Sanai, Milind Rajadhyaksha, Jonathan Liu

Proceedings Volume 10040, 100400W (2017) https://doi.org/10.1117/12.2250440

KEYWORDS: Tumors, Photons, Mirrors, Microscopes, Confocal microscopy, In vivo imaging, Cancer, Point-of-care devices, Pathology, Tissues

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SPIE Journal Paper | 5 September 2013 Open Access

High-sensitivity, real-time, ratiometric imaging of surface-enhanced Raman scattering nanoparticles with a clinically translatable Raman endoscope device

Ellis Garai, Steven Sensarn, Cristina Zavaleta, Dominique Van de Sompel, Nathan Loewke, Michael Mandella, Sanjiv Gambhir, Christopher Contag

JBO, Vol. 18, Issue 09, 096008, (September 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.9.096008

KEYWORDS: Nanoparticles, Surface enhanced Raman spectroscopy, Raman spectroscopy, Tissues, Endoscopes, Multimode fibers, Real time imaging, Raman scattering, Colon, Signal detection

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Proceedings Article | 13 March 2013 Paper

Handheld multispectral dual-axis confocal microscope for cervical cancer screening

Pongsak Sarapukdee, Santi Rattanavarin, Ungkarn Jarujareet, Numfon Khemthongcharoen, Romuald Jolivot, Il Woong Jung, Daniel López, Michael Mandella, Wibool Piyawattanametha

Proceedings Volume 8575, 85750V (2013) https://doi.org/10.1117/12.2004224

KEYWORDS: Microscopes, Confocal microscopy, Microelectromechanical systems, Scanners, Cervical cancer, Tissues, Cancer, In vivo imaging, Tissue optics, Colon

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SPIE Journal Paper | 2 March 2012 Open Access

In vivo near-infrared dual-axis confocal microendoscopy in the human lower gastrointestinal tract

Wibool Piyawattanametha, Hyejun Ra, Kevin Loewke, Michael Mandella, Christopher Contag, Zhen Qiu, Thomas Wang, Shai Friedland, Jonathan Liu, Gordon Kino, Olav Solgaard

JBO, Vol. 17, Issue 02, 021102, (March 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.2.021102

KEYWORDS: Confocal microscopy, In vivo imaging, Luminescence, Microelectromechanical systems, Tissues, Mirrors, Endoscopes, Colorectal cancer, Collimation, Scanners

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SPIE Journal Paper | 1 March 2010 Open Access

Micromirror-scanned dual-axis confocal microscope utilizing a gradient-index relay lens for image guidance during brain surgery

Jonathan Liu, Michael Mandella, Nathan Loewke, Henry Haeberle, Hyejun Ra, Wibool Piyawattanametha, Olav Solgaard, Gordon Kino, Christopher Contag

JBO, Vol. 15, Issue 02, 026029, (March 2010) https://doi.org/10.1117/12.10.1117/1.3386055

KEYWORDS: Microscopes, Relays, Microelectromechanical systems, Mirrors, Confocal microscopy, GRIN lenses, Gradient-index optics, Actuators, Brain, Neuroimaging

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Proceedings Article | 25 February 2010 Paper

Characterizing deep optical-sectioning microscopy performance with scattering phantoms and numerical simulations

Jonathan T. Liu, Michael Mandella, Gordon Kino, Christopher Contag

Proceedings Volume 7567, 756705 (2010) https://doi.org/10.1117/12.844315

KEYWORDS: Tissue optics, Scattering, Tissues, Monte Carlo methods, Confocal microscopy, Microscopes, Light scattering, Mirrors, Reflectivity, Objectives

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SPIE Journal Paper | 1 May 2008 Open Access

Efficient rejection of scattered light enables deep optical sectioning in turbid media with low-numerical-aperture optics in a dual-axis confocal architecture

Jonathan Liu, Michael Mandella, James Crawford, Christopher Contag, Thomas Wang, Gordon Kino

JBO, Vol. 13, Issue 03, 034020, (May 2008) https://doi.org/10.1117/12.10.1117/1.2939428

KEYWORDS: Scattering, Mirrors, Light scattering, Confocal microscopy, Tissue optics, Monte Carlo methods, Tissues, Luminescence, Microscopes, Esophagus

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Proceedings Article | 14 February 2007 Paper

Compact optical design for dual-axes confocal endoscopic microscopes

Michael Mandella, Jonathan Liu, Wibool Piyawattanametha, Hyejun Ra, Pei-Lin Hsiung, Larry Wong, Olav Solgaard, Thomas Wang, Christopher Contag, Gordon Kino

Proceedings Volume 6443, 64430E (2007) https://doi.org/10.1117/12.699484

KEYWORDS: Mirrors, Tissues, Microscopes, Microelectromechanical systems, Confocal microscopy, Natural surfaces, Endoscopy, In vivo imaging, Collimation, Scanners

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Proceedings Article | 14 February 2007 Paper

Mie scattering model for dual-axes confocal architecture

Larry Wong, Michael Mandella, Paul Holcomb, Gordon Kino, Thomas Wang

Proceedings Volume 6443, 64430R (2007) https://doi.org/10.1117/12.699437

KEYWORDS: Photons, Sensors, Tissues, Tissue optics, Scattering, Confocal microscopy, Light scattering, Monte Carlo methods, Mirrors, Mie scattering

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SPIE Journal Paper | 1 September 2006 Open Access

Dual-axes confocal reflectance microscope for distinguishing colonic neoplasia

Jonathan Liu, Michael Mandella, Shai Friedland, Roy Soetikno, James Crawford, Christopher Contag, Gordon Kino, Thomas Wang

JBO, Vol. 11, Issue 05, 054019, (September 2006) https://doi.org/10.1117/12.10.1117/1.2363363

KEYWORDS: Confocal microscopy, Microscopes, Reflectivity, Gaussian beams, Image resolution, Tissue optics, Light sources, Tissues, In vivo imaging, Light scattering

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Proceedings Article | 15 February 2006 Paper

A narrowband dual-axes confocal reflectance microscope for distinguishing colonic neoplasia

Jonathan Liu, Michael Mandella, Christopher Contag, Gordon Kino, Thomas Wang

Proceedings Volume 6090, 609004 (2006) https://doi.org/10.1117/12.649019

KEYWORDS: Confocal microscopy, Microscopes, Tissues, Tissue optics, Reflectivity, Image resolution, Light scattering, Light sources, Gaussian beams, Lenses

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Proceedings Article | 17 January 2005 Paper

Revolutionizing handwriting with a digital pen

Marek Alboszta, G. Zhang, Stewart Carl, Hector Gonzalez, Mike Mandella

Proceedings Volume 5675, (2005) https://doi.org/10.1117/12.588414

KEYWORDS: Digital signal processing, Cameras, Optical navigation, Imaging systems, Navigation systems, Signal processing, Image processing, Combined lens-mirror systems, Distortion, Edge detection

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Proceedings Article | 13 July 2004 Paper

Performance of dual axes confocal microscope for in vivo molecular and cellular imaging

Gordon Kino, Thomas Wang, Chris Contag, Michael Mandella, Ning Chan

Proceedings Volume 5324, (2004) https://doi.org/10.1117/12.530016

KEYWORDS: Confocal microscopy, Luminescence, Microscopes, Reflectivity, In vivo imaging, Objectives, Mirrors, Tissues, Tissue optics, Prototyping

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SPIE Journal Paper | 1 July 2004 Open Access

Confocal fluorescence microscope with dual-axis architecture and biaxial postobjective scanning

Thomas Wang, Christopher Contag, Michael Mandella, Ning Chan, Gordon Kino

JBO, Vol. 9, Issue 04, (July 2004) https://doi.org/10.1117/12.10.1117/1.1760760

KEYWORDS: Luminescence, Microscopes, Confocal microscopy, Signal to noise ratio, Green fluorescent protein, Tissues, Objectives, In vivo imaging, Lenses, Mirrors

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Showing 5 of 17 publications

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