Prof. Qingming Luo Profile

Prof. Qingming Luo

President at Hainan Univ

SPIE Involvement:

Publications (231)

Proceedings Article | 5 March 2021 Presentation

Welcome and Introduction to SPIE Conference 11629B

Qingming Luo, Jun Ding, Ling Fu

Proceedings Volume 11629, 1162909 (2021) https://doi.org/10.1117/12.2595475

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Proceedings Article | 5 March 2021 Poster + Paper

Prospective respiration-gated optical-resolution photoacoustic microscopy to eliminate motion artifacts caused by respiratory of mouse

Jianshuang Wei, Xianlin Song, Qun Wang, Qingming Luo, Xiaoquan Yang

Proceedings Volume 11640, 116400V (2021) https://doi.org/10.1117/12.2589234

KEYWORDS: Imaging systems, Photoacoustic imaging, Optical imaging, Photoacoustic microscopy, Bessel beams, Signal detection, Resonators, Photoacoustic spectroscopy, Optical resolution, Microrings

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Proceedings Article | 8 November 2020 Poster

Prospective respiration-gated photoacoustic microscopy for removing motion artifacts based on displacement sensor

Jianshuang Wei, Xianlin Song, Qun Wang, Jiali Wang, Qingming Luo, XiaoQuan Yang

Proceedings Volume 11525, 1152524 (2020) https://doi.org/10.1117/12.2580186

KEYWORDS: Sensors, Photoacoustic microscopy, Visualization, Vascular imaging, Ultrasonography, Signal detection, Optical imaging, In vivo imaging, Data acquisition, Carbon

Proceedings Article | 12 October 2020 Open Access

Brain-wide positioning system for brainsmatics (Conference Presentation)

Qingming Luo

Proceedings Volume 11553, 1155302 (2020) https://doi.org/10.1117/12.2583898

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Proceedings Article | 7 March 2019 Presentation

Targeting delivery of nanovaccine/nanoimmunomudulator based on peptide-lipid nanoparticle for immunotherapy in vivo (Conference Presentation)

Zhihong Zhang, Lisen Lu, Yuan Qian, Sha Qiao, Qingming Luo

Proceedings Volume 10879, 108790D (2019) https://doi.org/10.1117/12.2507601

KEYWORDS: Nanoparticles, In vivo imaging, Tumors, Melanoma, Lymphatic system, Cancer, Therapeutic agents, Near infrared, Receptors

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Proceedings Article | 27 February 2019 Paper

Multifocus optical-resolution photoacoustic microscope for extended depth of field

Xianlin Song, Xiaoquan Yang, Bowen Jiang, Qingming Luo

Proceedings Volume 10878, 108782Y (2019) https://doi.org/10.1117/12.2505023

KEYWORDS: Microscopes, Signal detection, Biomedical optics

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Proceedings Article | 14 March 2018 Presentation

Advanced NeuroGPS-Tree achieves brain-wide reconstruction of neuronal population equal to manual reconstruction level (Conference Presentation)

Tingwei Quan, Hang Zhou, Shiwei Li, Qingming Luo, Hui Gong, Anan Li, Shaoqun Zeng

Proceedings Volume 10481, 104810N (2018) https://doi.org/10.1117/12.2295110

KEYWORDS: Neurons, Neuroimaging, Brain, Neuroscience, Brain imaging, Image resolution, 3D visualizations, 3D modeling, Reconstruction algorithms

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Proceedings Article | 19 April 2017 Presentation

ReagentTF: a rapid and versatile optical clearing method for biological imaging (Conference Presentation)

Tingting Yu, Jingtan Zhu, Yusha Li, Yisong Qi, Jianyi Xu, Hui Gong, Qingming Luo, Dan Zhu

Proceedings Volume 10051, 100510J (2017) https://doi.org/10.1117/12.2253491

KEYWORDS: Lithium, Current controlled current source, Optical clearing, Luminescence, Tissues, Brain, Fluorescent proteins, Visualization

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Proceedings Article | 19 April 2017 Presentation

High-throughput dual-color precision imaging for brain-wide mapping of the connectome with cytoarchitectonic landmarks at the cellular level (Conference Presentation)

Qingming Luo, Hui Gong, Jing Yuan, Xiangning Li, Anan Li, Tonghui Xu

Proceedings Volume 10051, 100510D (2017) https://doi.org/10.1117/12.2251624

KEYWORDS: Lithium, Brain, Neurons, Neuroimaging, Image processing, Brain mapping, Tomography, 3D image processing, Tissues, Image resolution

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Proceedings Article | 8 February 2017 Presentation + Paper

Stress plays provoking role in hypertension-related stroke: injuries of blood-brain barrier function

O. Semyachkina-Glushkovskaya, A. Shirokov, A. Gekalyuk, M. Abakumov, N. Navolokin, A. Abdurashitov, A. Pavlov, M. Ulanova, V. Fedorova, V. Razubaeva, E. Saranceva, P. Li, Q. Huang, D. Zhu, Q. Luo, V. Tuchin, J. Kurths

Proceedings Volume 10051, 100510I (2017) https://doi.org/10.1117/12.2251481

KEYWORDS: Blood brain barrier, Brain, Laser optics, Neuroimaging, Optical imaging, Blood pressure, Confocal microscopy, Gadolinium, Magnetic resonance imaging, Laser speckle imaging, Injuries, Laser speckle contrast imaging, Speckle, Resistance

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Proceedings Article | 27 April 2016 Paper

Cerebral venous circulatory disturbance as an informative prognostic marker for neonatal hemorrhagic stroke

Oxana Semyachkina-Glushkovskaya, Alexey Pavlov, Nikita Navolokin, Vladislav Lychagov, Arkady Abdurashitov, Ekaterina Zinchenko, Artemiy Gekaluk, Dan Zhu, Rui Shi, Qingming Luo, Valery Tuchin

Proceedings Volume 9887, 98872I (2016) https://doi.org/10.1117/12.2225489

KEYWORDS: Brain, Veins, Laser speckle contrast imaging, Neuroimaging, Brain, Veins, Blood, Neuroimaging, Animal model studies, Optical coherence tomography, Photoacoustic spectroscopy, Magnetic resonance imaging, Hypoxia, Blood circulation, Tissues, Doppler tomography, Cerebral blood flow, Hemodynamics

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Proceedings Article | 26 April 2016 Presentation

Fast whole-brain optical tomography capable of automated slice-collection (Conference Presentation)

Jing Yuan, Tao Jiang, Lei Deng, Beng Long, Jie Peng, Qingming Luo, Hui Gong

Proceedings Volume 9690, 969013 (2016) https://doi.org/10.1117/12.2211595

KEYWORDS: Brain, Optical tomography, Neuroimaging, Imaging systems, Tissue optics, Proteins, Composites, Brain mapping, Tissues, Optical microscopy

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SPIE Journal Paper | 11 March 2016 Open Access

Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol

Tingting Yu, Yisong Qi, Jianru Wang, Wei Feng, Jianyi Xu, Jingtan Zhu, Yingtao Yao, Hui Gong, Qingming Luo, Dan Zhu

JBO, Vol. 21, Issue 08, 081203, (March 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.8.081203

KEYWORDS: Brain, Luminescence, Optical clearing, Neuroimaging, Tissues, Green fluorescent protein, Tissue optics, Optical imaging, Neurons, Collagen

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Proceedings Article | 19 March 2015 Paper

Comparison of cerebral microcirculation of alloxan diabetes and healthy mice using laser speckle contrast imaging

Polina Timoshina, Rui Shi, Yang Zhang, Dan Zhu, Oxana Semyachkina-Glushkovskaya, Valery Tuchin, Qingming Luo

Proceedings Volume 9448, 94480B (2015) https://doi.org/10.1117/12.2179988

KEYWORDS: Glucose, Blood circulation, Brain, Veins, Blood, Speckle, Blood vessels, Laser speckle imaging, Animal model studies, Laser speckle contrast imaging

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Proceedings Article | 19 March 2015 Paper

Detrended fluctuation analysis of cerebral venous dynamics in newborn mice with intracranial hemorrhage

A. Pavlov, O. Semyachkina-Glushkovskaya, O. Bibikova, O. Pavlova, Y. Mohammad, Q. Huang, D. Zhu, P. Li, V. Tuchin, Q. Luo

Proceedings Volume 9448, 94481I (2015) https://doi.org/10.1117/12.2178841

KEYWORDS: Laser speckle contrast imaging, Diagnostics, Blood circulation, Statistical analysis, Medicine, Biomedical optics, Photonics, Light scattering, Scattering, Data processing

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Proceedings Article | 10 March 2015 Paper

Optimized optical clearing method for imaging central nervous system

Tingting Yu, Yisong Qi, Hui Gong, Qingming Luo, Dan Zhu

Proceedings Volume 9305, 930527 (2015) https://doi.org/10.1117/12.2078736

KEYWORDS: Brain, Luminescence, Photoacoustic tomography, Tissues, Transparency, Green fluorescent protein, Optical clearing, Imaging systems, Nervous system, Neuroimaging

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Proceedings Article | 5 March 2015 Paper

Cerebral venous dynamics in newborn mice with intracranial hemorrhage studied using wavelets

A. Pavlov, O. Semyachkina-Glushkovskaya, O. Sindeeva, O. Pavlova, E. Shuvalova, Q. Huang, D. Zhu, P. Li, V. Tuchin, Q. Luo

Proceedings Volume 9322, 932214 (2015) https://doi.org/10.1117/12.2076753

KEYWORDS: Blood circulation, Wavelets, Laser speckle contrast imaging, Heart, Biomedical optics, Photonics, Optoelectronics, Cerebral blood flow, Diagnostics, Medicine

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SPIE Journal Paper | 3 February 2015 Open Access

Decoupled fluorescence Monte Carlo model for direct computation of fluorescence in turbid media

Zhaoyang Luo, Yong Deng, Kan Wang, Lichao Lian, Xiaoquan Yang, Qingming Luo

JBO, Vol. 20, Issue 02, 025002, (February 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.2.025002

KEYWORDS: Luminescence, Photons, Monte Carlo methods, Scattering, Atrial fibrillation, Absorption, Sensors, Statistical modeling, Charge-coupled devices, Computer simulations

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SPIE Journal Paper | 22 August 2014 Open Access

Optimization of sample cooling temperature for redox cryo-imaging

Anle Wang, Jing Yuan, Weihua Luo, Mengmeng Liu, Qingming Luo

JBO, Vol. 19, Issue 08, 080502, (August 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.8.080502

KEYWORDS: Temperature metrology, Tissues, Brain, Luminescence, Liquids, Nitrogen, Natural surfaces, Biomedical optics, Tissue optics, Biological research

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SPIE Journal Paper | 26 May 2014 Open Access

Studying hemispheric lateralization during a Stroop task through near-infrared spectroscopy-based connectivity

Lei Zhang, Jinyan Sun, Bailei Sun, Qingming Luo, Hui Gong

JBO, Vol. 19, Issue 05, 057012, (May 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.5.057012

KEYWORDS: Near infrared spectroscopy, Brain, Hemodynamics, Neuroimaging, Spectroscopy, Brain imaging, Data conversion, Sun, Data analysis, Functional magnetic resonance imaging

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Proceedings Article | 20 March 2014 Paper

Technical considerations on confocal based fluorescence micro-optical sectioning tomography for visualizing brain circuits

Xiaoli Qi, Xiaohua Lv, Hanqing Xiong, Cheng Yan, Jianling Chen, Hui Gong, Qingming Luo, Shaoqun Zeng

Proceedings Volume 8928, 89280T (2014) https://doi.org/10.1117/12.2036645

KEYWORDS: Brain, Neuroimaging, Confocal microscopy, Luminescence, Image resolution, Tomography, Imaging systems, Fluorescence tomography, Biomedical optics, Visualization

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Proceedings Article | 5 March 2014 Paper

Studying hemispheric lateralization during a Stroop task by near-infrared spectroscopy

Lei Zhang, Jinyan Sun, Bailei Sun, Qingming Luo, Hui Gong

Proceedings Volume 8928, 892814 (2014) https://doi.org/10.1117/12.2039712

KEYWORDS: Near infrared spectroscopy, Hemodynamics, Brain, Data conversion, Prefrontal cortex, Wavelet transforms, Continuous wave operation, Brain activation, Sensors, Electrodes

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SPIE Journal Paper | 27 January 2014 Open Access

Preclinical evidence of mitochondrial nicotinamide adenine dinucleotide as an effective alarm parameter under hypoxia

Hua Shi, Nannan Sun, Avraham Mayevsky, Zhihong Zhang, Qingming Luo

JBO, Vol. 19, Issue 01, 017005, (January 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.1.017005

KEYWORDS: Hypoxia, Electrocardiography, Reflectivity, Oxygen, Tissues, Luminescence, Brain, Cerebral blood flow, Arteries, Nitrogen

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SPIE Journal Paper | 25 September 2013 Open Access

Correlation between hemodynamic and electrophysiological signals dissociates neural correlates of conflict detection and resolution in a Stroop task: a simultaneous near-infrared spectroscopy and event-related potential study

Jinyan Sun, Bailei Sun, Lei Zhang, Qingming Luo, Hui Gong

JBO, Vol. 18, Issue 09, 096014, (September 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.9.096014

KEYWORDS: Near infrared spectroscopy, Hemodynamics, Electrodes, Brain, Statistical analysis, Electroencephalography, Sensors, Signal detection, Signal processing, Prefrontal cortex

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SPIE Journal Paper | 11 June 2013 Open Access

Fast optical sectioning obtained by structured illumination microscopy using a digital mirror device

Dongli Xu, Tao Jiang, Anan Li, Bihe Hu, Zhao Feng, Hui Gong, Shaoqun Zeng, Qingming Luo

JBO, Vol. 18, Issue 06, 060503, (June 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.6.060503

KEYWORDS: Brain, Digital micromirror devices, Mirrors, Microscopy, Neuroimaging, Imaging systems, 3D image processing, Biomedical optics, Luminescence, Neuroscience

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SPIE Journal Paper | 28 May 2013 Open Access

Improved detectability of neuronal connectivity on mechanical sectioning setup by using confocal detection

Xiaoli Qi, Hanqing Xiong, Xiaohua Lv, Jianling Chen, Hui Gong, Qingming Luo, Shaoqun Zeng

JBO, Vol. 18, Issue 05, 050506, (May 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.5.050506

KEYWORDS: Confocal microscopy, Signal detection, Luminescence, Optical tomography, Tomography, Imaging systems, Neuroimaging, Brain, Image resolution, Mechanics

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SPIE Journal Paper | 21 February 2013 Open Access

1064 nm-Nd:YAG lasers with different output modes enhancing transdermal delivery: physical and physiological mechanisms

Caihua Liu, Jie Zhang, Yuanlei Yue, Qingming Luo, Dan Zhu

JBO, Vol. 18, Issue 06, 061228, (February 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.6.061228

KEYWORDS: Skin, Laser irradiation, Molecular lasers, Temperature metrology, Reflectivity, Laser tissue interaction, Molecules, Pulsed laser operation, Thermography, In vivo imaging

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Proceedings Article | 11 December 2012 Paper

Quadratic trianqular element for diffuse optical tomography

Xuanxuan Zhang, Yong Deng, Jun Xu, Zhaoyang Luo, Hui Gong, Qingming Luo

Proceedings Volume 8553, 85532G (2012) https://doi.org/10.1117/12.2001501

KEYWORDS: Chemical elements, Finite element methods, Linear elements, Diffuse optical tomography, Optical components, Scattering, Biomedical optics, Matrices, Photons, Tissue optics

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SPIE Journal Paper | 3 December 2012 Open Access

Dynamic change of collateral flow varying with distribution of regional blood flow in acute ischemic rat cortex

Zhen Wang, Weihua Luo, Fangyuan Zhou, Pengcheng Li, Qingming Luo

JBO, Vol. 17, Issue 12, 125001, (December 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.12.125001

KEYWORDS: Blood circulation, Ischemia, Blood, Brain, Laser speckle contrast imaging, Ischemic stroke, Arteries, Tissues, Speckle, Cerebral blood flow

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SPIE Journal Paper | 8 August 2012 Open Access

Micro-computed tomography-guided, non-equal voxel Monte Carlo method for reconstruction of fluorescence molecular tomography

Guotao Quan, Kan Wang, Xiaoquan Yang, Yong Deng, Qingming Luo, Hui Gong

JBO, Vol. 17, Issue 8, 086006, (August 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.8.086006

KEYWORDS: Monte Carlo methods, Luminescence, Optical properties, Glasses, Fluorescence tomography, Tomography, Tissue optics, Inverse problems, Photons, Image segmentation

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SPIE Journal Paper | 31 July 2012 Open Access

In vivo imaging of hemodynamics and oxygen metabolism in acute focal cerebral ischemic rats with laser speckle imaging and functional photoacoustic microscopy

Zilin Deng, Zhen Wang, Xiaoquan Yang, Qingming Luo, Hui Gong

JBO, Vol. 17, Issue 8, 081415, (July 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.8.081415

KEYWORDS: Ischemia, Hemodynamics, Oxygen, Arteries, Veins, Mode conditioning cables, In vivo imaging, Photoacoustic spectroscopy, Blood, Brain

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SPIE Journal Paper | 7 May 2012 Open Access

Early monitoring of cerebral hypoperfusion in rats by laser speckle imaging and functional photoacoustic microscopy

Hui Wang, Xiaoquan Yang, Zhen Wang, Zilin Deng, Hui Gong, Qingming Luo

JBO, Vol. 17, Issue 6, 061207, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.6.061207

KEYWORDS: Brain, Blood vessels, Arteries, Blood, Oxygen, Veins, Cerebral cortex, Neuroimaging, Hemodynamics, Tissues

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SPIE Journal Paper | 1 November 2011 Open Access

Dedicated hardware processor and corresponding system-on-chip design for real-time laser speckle imaging

Chao Jiang, Hongyan Zhang, Jia Wang, Yaru Wang, Heng He, Rui Liu, Fangyuan Zhou, Jialiang Deng, Pengcheng Li, Qingming Luo

JBO, Vol. 16, Issue 11, 116008, (November 2011) https://doi.org/10.1117/12.10.1117/1.3651772

KEYWORDS: Field programmable gate arrays, Image processing, LCDs, Video, Blood circulation, CCD cameras, Control systems, Cameras, Clocks, System on a chip

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SPIE Journal Paper | 1 September 2011 Open Access

Quantitative analysis of dehydration in porcine skin for assessing mechanism of optical clearing

Tingting Yu, Xiang Wen, Qingming Luo, Dan Zhu, Valery Tuchin

JBO, Vol. 16, Issue 09, 095002, (September 2011) https://doi.org/10.1117/12.10.1117/1.3621515

KEYWORDS: Skin, Optical clearing, Scattering, Water, Reflectivity, Absorption, Transmittance, Refractive index, Tissue optics, Quantitative analysis

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Proceedings Article | 12 April 2011 Paper

Mechanism for tissue optical clearing: physical and physiological research

Xiang Wen, Tingting Yu, Qingming Luo, Dan Zhu

Proceedings Volume 7999, 79990F (2011) https://doi.org/10.1117/12.889229

KEYWORDS: Optical clearing, Skin, Scattering, Tissues, Tissue optics, Mie scattering, Refractive index, Water, Collagen, In vivo imaging

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SPIE Journal Paper | 1 April 2011 Open Access

Visualization of light propagation in visible Chinese human head for functional near-infrared spectroscopy

Ting Li, Hui Gong, Qingming Luo

JBO, Vol. 16, Issue 04, 045001, (April 2011) https://doi.org/10.1117/12.10.1117/1.3567085

KEYWORDS: Head, Brain, Signal detection, Cerebral cortex, Monte Carlo methods, Tissues, Visible radiation, Visualization, Data modeling, Brain activation

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SPIE Journal Paper | 1 February 2011 Open Access

Monte Carlo-based fluorescence molecular tomography reconstruction method accelerated by a cluster of graphic processing units

Guotao Quan, Hui Gong, Yong Deng, Jianwei Fu, Qingming Luo

JBO, Vol. 16, Issue 02, 026018, (February 2011) https://doi.org/10.1117/12.10.1117/1.3544548

KEYWORDS: Monte Carlo methods, Luminescence, Computing systems, Fluorescence tomography, Tomography, Finite element methods, Computer simulations, Tissue optics, Graphics processing units, Visualization

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SPIE Journal Paper | 1 May 2010 Open Access

Characteristics of calcium signaling in astrocytes induced by photostimulation with femtosecond laser

Yuan Zhao, Yuan Zhang, Wei Zhou, Xiuli Liu, Shaoqun Zeng, Qingming Luo

JBO, Vol. 15, Issue 03, 035001, (May 2010) https://doi.org/10.1117/12.10.1117/1.3454390

KEYWORDS: Calcium, Femtosecond phenomena, Photostimulation, Acquisition tracking and pointing, Wave propagation, Luminescence, Brain, Receptors, Neurons, Ions

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SPIE Journal Paper | 1 March 2010 Open Access

Imaging dermal blood flow through the intact rat skin with an optical clearing method

Dan Zhu, Jing Wang, Zhongwei Zhi, Xiang Wen, Qingming Luo

JBO, Vol. 15, Issue 02, 026008, (March 2010) https://doi.org/10.1117/12.10.1117/1.3369739

KEYWORDS: Skin, Optical clearing, Blood circulation, Laser speckle contrast imaging, Scattering, Speckle, In vitro testing, In vivo imaging, Blood vessels, Transmittance

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SPIE Journal Paper | 1 January 2010 Open Access

Spatiotemporal laser speckle contrast analysis for blood flow imaging with maximized speckle contrast

Jianjun Qiu, Pengcheng Li, Weihua Luo, Jia Wang, Hongyan Zhang, Qingming Luo

JBO, Vol. 15, Issue 01, 016003, (January 2010) https://doi.org/10.1117/12.10.1117/1.3290804

KEYWORDS: Speckle, Blood circulation, Laser speckle contrast imaging, Error analysis, Statistical analysis, Speckle imaging, Computer simulations, Biological research, Numerical simulations, In vivo imaging

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SPIE Journal Paper | 1 January 2010 Open Access

Special method to prepare quantum dot probes with reduced cytotoxicity and increased optical property

Hai-Li Zhang, Yong-Qiang Li, Jian-Hao Wang, Xiang-Ning Li, Song Lin, Yuan-Di Zhao, Qingming Luo

JBO, Vol. 15, Issue 01, 015001, (January 2010) https://doi.org/10.1117/12.10.1117/1.3291999

KEYWORDS: Luminescence, Quantum dots, Zinc, Optical properties, Proteins, Capillaries, Sodium, Spectroscopy, Cadmium, Quantum efficiency

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Proceedings Article | 6 March 2009 Paper

The multiple parameter hemodynamic imaging system based on ARM

Xuejun Tang, Heng He, Chao Jiang, Pengcheng Li, Qingming Luo

Proceedings Volume 7280, 72800Y (2009) https://doi.org/10.1117/12.823352

KEYWORDS: Imaging systems, Hemodynamics, Optical imaging, Control systems, Embedded systems, Light emitting diodes, Cerebral blood flow, LCDs, Human-machine interfaces, Laser speckle contrast imaging

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Proceedings Article | 6 March 2009 Paper

Randomized trial comparing exercise therapy, alternating cold and hot therapy, and low intensity laser therapy for chronic lumbar muscle strain

Xiaoguang Liu, Jie Li, Timon Chengyi Liu, Jianqin Yuan, Qingming Luo

Proceedings Volume 7280, 72801B (2009) https://doi.org/10.1117/12.823363

KEYWORDS: Low-intensity laser therapy, Laser therapeutics, Laser irradiation, Visualization, Tissues, Blood circulation, Clinical trials, Injuries, Motion measurement, Nerve

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Proceedings Article | 6 March 2009 Paper

Impact of magnification of imaging system on laser speckle contrast imaging

Jianjun Qiu, Hongyan Zhang, Pengcheng Li, Qingming Luo

Proceedings Volume 7280, 72800Z (2009) https://doi.org/10.1117/12.823356

KEYWORDS: Speckle, Laser speckle contrast imaging, Imaging systems, Blood circulation, In vivo imaging, Speckle pattern, Laser scattering, Cerebral blood flow, Biomedical optics, Scattering

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Proceedings Article | 17 February 2009 Paper

Developing new fluorescent proteins with stagger extension process

Jie Yang, Jinling Lu, Haiming Luo, Qingming Luo, Zhihong Zhang

Proceedings Volume 7191, 71910H (2009) https://doi.org/10.1117/12.811377

KEYWORDS: Luminescence, Proteins, Fluorescent proteins, Green fluorescent protein, Quantum efficiency, Venus, Biomedical optics, Fluorescence resonance energy transfer, Mass attenuation coefficient, Lutetium

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Proceedings Article | 17 February 2009 Paper

A new red bimolecular fluorescence complementation based on TagRFP

Lingsong Qin, Jun Chu, Ying Zheng, Qingming Luo, Shaoqun Zeng, Zhihong Zhang

Proceedings Volume 7191, 71910G (2009) https://doi.org/10.1117/12.811375

KEYWORDS: Luminescence, Proteins, Fluorescent proteins, Ferroelectric materials, In vivo imaging, Visualization, Visual analytics, Chromophores, Molecular mechanisms, Signal processing

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Proceedings Article | 12 February 2009 Paper

The generation of the synchronized burst in the cultured neuronal networks

Xiangning Li, Jing Sun, Wenjuan Chen, Shaoqun Zeng, Qingming Luo

Proceedings Volume 7176, 71760H (2009) https://doi.org/10.1117/12.812343

KEYWORDS: Neurons, Electrodes, Brain, In vitro testing, Lithium, Data processing, Neural networks, Sun, Receptors, Raster graphics

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SPIE Journal Paper | 1 November 2008 Open Access

Acute hyperglycemia compromises cerebral blood flow following cortical spreading depression in rats monitored by laser speckle imaging

Zhen Wang, Weihua Luo, Pengcheng Li, Jianjun Qiu, Qingming Luo

JBO, Vol. 13, Issue 06, 064023, (November 2008) https://doi.org/10.1117/12.10.1117/1.3041710

KEYWORDS: Laser speckle imaging, Glucose, Cerebral blood flow, Blood circulation, Ischemic stroke, Speckle, Brain, Printed circuit board testing, Capillaries, Oxygen

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SPIE Journal Paper | 1 May 2008 Open Access

Activation of caspase-3 noninvolved in the bystander effect of the herpes simplex virus thymidine kinase gene/ganciclovir (HSV-tk/GCV) system

Zhihong Zhang, Juqiang Lin, Jun Chu, Yan Ma, Shaoqun Zeng, Qingming Luo

JBO, Vol. 13, Issue 03, 031209, (May 2008) https://doi.org/10.1117/12.10.1117/1.2937830

KEYWORDS: Fluorescence resonance energy transfer, Luminescence, Cell death, Multichannel imaging systems, Imaging systems, Green fluorescent protein, Proteins, Fluorescent proteins, Image fusion, Optoelectronics

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Proceedings Article | 14 March 2008 Paper

Hemodynamic and electrophysiological responses to functional activation accessed by multi-wavelength optical imaging and electrophysiological recording system

Nengyun Feng, Yuan Liu, Wenjia Wang, Qingming Luo, Pengcheng Li

Proceedings Volume 6863, 68630B (2008) https://doi.org/10.1117/12.763347

KEYWORDS: Imaging systems, Optical imaging, Light emitting diodes, Speckle, Hemodynamics, Laser speckle imaging, Blood circulation, Brain, Spectroscopy, Imaging spectroscopy

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Proceedings Article | 14 March 2008 Paper

Effects of sciatic nerve stimulation on the propagation of cortical spreading depression

Xiaoli Sun, Zhidong Yu, Shaoqun Zeng, Qingming Luo, Pengcheng Li

Proceedings Volume 6863, 68630U (2008) https://doi.org/10.1117/12.763372

KEYWORDS: Nerve, Electrodes, Brain stimulation, Brain, Epilepsy, Electrophysiology, Ischemia, Optical imaging, Modulation, Positron emission tomography

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SPIE Journal Paper | 1 March 2008 Open Access

Short-term and long-term effects of optical clearing agents on blood vessels in chick chorioallantoic membrane

Dan Zhu, Jing Zhang, Han Cui, Zongzhen Mao, Pengcheng Li, Qingming Luo

JBO, Vol. 13, Issue 02, 021106, (March 2008) https://doi.org/10.1117/12.10.1117/1.2907169

KEYWORDS: Blood vessels, Glucose, Optical clearing, Blood circulation, Content addressable memory, Tissue optics, Speckle, Laser speckle contrast imaging, Photography, Blood

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Proceedings Article | 28 February 2008 Paper

Enlarging the linear response range of velocity with optimum imaging parameters and modified data processing in laser speckle imaging

Jianjun Qiu, Pengcheng Li, Sergey Ul'yanov, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6863, 68630T (2008) https://doi.org/10.1117/12.763355

KEYWORDS: Speckle, CCD cameras, Laser speckle imaging, Speckle pattern, Velocity measurements, Microscopy, Data processing, Imaging systems, Blood circulation, Cerebral blood flow

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Proceedings Article | 18 February 2008 Paper

Simultaneous imaging of two initiator caspases during cisplatin-induced HeLa apoptosis

Jun Chu, Liang Wang, Qingming Luo, Zhihong Zhang

Proceedings Volume 6857, 68570R (2008) https://doi.org/10.1117/12.767864

KEYWORDS: Cell death, Fluorescence resonance energy transfer, Fluorescent proteins, Luminescence, Proteins, Biosensors, Green fluorescent protein, Imaging systems, Image processing, Digital image correlation

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Proceedings Article | 13 February 2008 Paper

Caspase-3-independent pathways proceeding in bystander effect of HSV-tk/GCV system

Juqiang Lin, Yan Ma, Shaoqun Zeng, Zhihong Zhang

Proceedings Volume 6868, 68680B (2008) https://doi.org/10.1117/12.763385

KEYWORDS: Fluorescence resonance energy transfer, Cell death, Imaging systems, Cancer, Tumors, Oncology, Fluorescent proteins, Visualization, Luminescence, RGB color model

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Proceedings Article | 13 February 2008 Paper

Visualization of EGFR and Grb2 interaction using bimolecular fluorescence complementation

Xiangyong Li, Jun Chu, Qingming Luo, Zhihong Zhang

Proceedings Volume 6868, 68680T (2008) https://doi.org/10.1117/12.763411

KEYWORDS: Proteins, Visualization, Luminescence, Receptors, Venus, Fluorescent proteins, Particles, Green fluorescent protein, Molecules, Lithium

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Proceedings Article | 6 February 2008 Paper

Bifurcation and chaos in the spontaneously firing spike train of cultured neuronal network

Wenjuan Chen, Xiangning Li, Geng Zhu, Wei Zhou, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6855, 68550E (2008) https://doi.org/10.1117/12.763403

KEYWORDS: Chaos, Time series analysis, Neurons, Neuroscience, Biomedical optics, Photonics, Neural networks, Stochastic processes, Brain mapping, Lithium

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Proceedings Article | 8 January 2008 Paper

Measurement of caspase-2 activation during different anti-tumor drugs induced apoptosis by FRET technique

Juqiang Lin, Shaoqun Zeng, Qingming Luo, Chen Rong, Zhihong Zhang

Proceedings Volume 6826, 682630 (2008) https://doi.org/10.1117/12.757313

KEYWORDS: Fluorescence resonance energy transfer, Cell death, Fluorescent proteins, Cancer, Biomedical optics, Proteins, Optoelectronics, Imaging systems, Medicine, Photonics

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SPIE Journal Paper | 1 January 2008

Effective method for automatic contour extraction

Zheng Fang, Qingming Luo, Qian Liu, Kun Bi, Xiaomin Sun

JEI, Vol. 17, Issue 01, 013016, (January 2008) https://doi.org/10.1117/12.10.1117/1.2885248

KEYWORDS: Image segmentation, Computed tomography, Reconstruction algorithms, Tomography, Sensors, X-rays, Detection and tracking algorithms, Charge-coupled devices, X-ray computed tomography, Computer simulations

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SPIE Journal Paper | 1 January 2008 Open Access

Fluorescence imaging to assess the matrix metalloproteinase activity and its inhibitor in vivo

Zhihong Zhang, Jie Yang, Jinling Lu, Juqiang Lin, Shaoqun Zeng, Qingming Luo

JBO, Vol. 13, Issue 01, 011006, (January 2008) https://doi.org/10.1117/12.10.1117/1.2830659

KEYWORDS: Luminescence, Tumors, In vivo imaging, Sensors, Proteins, Fluorescence resonance energy transfer, Content addressable memory, Signal detection, Confocal microscopy, Imaging systems

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SPIE Journal Paper | 1 November 2007 Open Access

Effect of light losses of sample between two integrating spheres on optical properties estimation

Dan Zhu, Wei Lu, Shaoqun Zeng, Qingming Luo

JBO, Vol. 12, Issue 06, 064004, (November 2007) https://doi.org/10.1117/12.10.1117/1.2815691

KEYWORDS: Error analysis, Absorption, Optical properties, Scattering, Statistical analysis, Integrating spheres, Light scattering, Distributed interactive simulations, Anisotropy, Tissue optics

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Proceedings Article | 1 May 2007 Paper

Enhancement of spontaneous burst activity of hippocampal neuronal networks with low frequency close-loop stimulation

Yanling Li, Wei Zhou, Shaoqun Zeng, Xiangning Li, Man Liu, Qingming Luo

Proceedings Volume 6534, 65343C (2007) https://doi.org/10.1117/12.741465

KEYWORDS: Neurons, Electrodes, Action potentials, In vitro testing, Modulation, Synaptic transmission, Plating, Brain, Glia, Lithium

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Proceedings Article | 1 May 2007 Paper

Quantifying the properties of high scattering media with Mueller matrix

Yong Deng, Qiang Lu, Qingming Luo

Proceedings Volume 6534, 653436 (2007) https://doi.org/10.1117/12.741456

KEYWORDS: Scattering, Light scattering, Backscatter, Particles, Polarization, Mie scattering, Monte Carlo methods, Scattering media, Multiple scattering, Optical spheres

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Proceedings Article | 1 May 2007 Paper

Restoration of fluorescence images from two-photon microscopy using modified nonlinear anisotropic diffusion filter

Hongmin Zhang, Qingming Luo, Shaoqun Zeng

Proceedings Volume 6534, 65343H (2007) https://doi.org/10.1117/12.741498

KEYWORDS: Diffusion, Luminescence, Anisotropic diffusion, Nonlinear filtering, Neurons, Anisotropic filtering, Image filtering, Two photon excitation microscopy, Laser scanners, Image restoration

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Proceedings Article | 1 May 2007 Paper

A novel analysis method for near infrared spectroscopy based on Hilbert-Huang transform

Zhenyu Zhou, Hongyu Yang, Yun Liu, Zongcai Ruan, Qingming Luo, Hui Gong, Zuhong Lu

Proceedings Volume 6534, 653417 (2007) https://doi.org/10.1117/12.741479

KEYWORDS: Wavelets, Cerebral blood flow, Signal processing, Brain, Near infrared, Interference (communication), Signal analyzers, Fourier transforms, Prefrontal cortex, Data modeling

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Proceedings Article | 1 May 2007 Paper

A biomedical information system for neuroimaging and brain function

Jun You, Jie Zhang, Qingming Luo

Proceedings Volume 6534, 65343E (2007) https://doi.org/10.1117/12.741467

KEYWORDS: Databases, Neuroimaging, Brain, Biomedical optics, Neuroscience, Data modeling, Brain-machine interfaces, Photonics, Knowledge discovery, Imaging systems

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Proceedings Article | 1 May 2007 Paper

Different hemodynamic response of prefontal area for men and women to mental arithmetic: a near-infrared spectroscopy study

Hongyu Yang, Zhenyu Zhou, Yun Liu, Zongcai Ruan, Hui Gong, Qingming Luo, Zuhong Lu

Proceedings Volume 6534, 653410 (2007) https://doi.org/10.1117/12.741473

KEYWORDS: Near infrared spectroscopy, Prefrontal cortex, Hemodynamics, Brain, Statistical analysis, Neuroimaging, Blood, Functional magnetic resonance imaging, Sensors, Photonics

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Proceedings Article | 1 May 2007 Paper

Modulation of temperature on optical properties of rat skin in vivo

Qing Ouyang, Dan Zhu, Qihuan Luo, Hui Gong, Qingming Luo

Proceedings Volume 6534, 65343I (2007) https://doi.org/10.1117/12.741499

KEYWORDS: Skin, Temperature metrology, Reflectivity, Scattering, Absorption, Optical properties, Tissue optics, In vivo imaging, Light scattering, Optical fibers

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Proceedings Article | 1 May 2007 Paper

Low intensity laser treatment of nerve injuries

Xiao-Guang Liu, Timon Cheng-Yi Liu, Qing-Ming Luo

Proceedings Volume 6534, 65343P (2007) https://doi.org/10.1117/12.741565

KEYWORDS: Nerve, Injuries, Spinal cord, Laser therapeutics, Laser dentistry, Laser irradiation, Helium neon lasers, Lithium, Tissues, Nerve regeneration

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Proceedings Article | 1 May 2007 Paper

Dynamic imaging of cerebral blood flow in rat reperfused mini-stroke model using laser speckle temporal contrast analysis

Zhen Wang, Weihua Luo, Pengcheng Li, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6534, 65343N (2007) https://doi.org/10.1117/12.741504

KEYWORDS: Speckle, Cerebral blood flow, Ischemia, Somatosensory cortex, Laser tissue interaction, Spatial resolution, Brain, Blood circulation, Laser speckle imaging, Laser scattering

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Proceedings Article | 1 May 2007 Paper

Noninvasive blood glucose measurement system based on three wavelengths in near-infrared region

Yaqin Chen, Ge Bai, Jun Xiao, Long Wang, Qingming Luo

Proceedings Volume 6534, 653434 (2007) https://doi.org/10.1117/12.741454

KEYWORDS: Glucose, Blood, Absorption, Signal detection, Optical amplifiers, Near infrared, Near infrared spectroscopy, Light sources, Modulation, Statistical analysis

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Proceedings Article | 1 May 2007 Paper

Photoinactivation of bacteria of P. Aeruginosa: role of light coherence

Onega Ulianova, Sibo Zhou, Zhihong Zhang, Sergey Ulyanov, Qingming Luo

Proceedings Volume 6534, 65343Q (2007) https://doi.org/10.1117/12.741566

KEYWORDS: Oxygen, Molecules, Bacteria, Molecular interactions, Speckle, Mathematical modeling, Laser tissue interaction, Laser therapeutics, Temporal coherence, Computer simulations

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Proceedings Article | 1 May 2007 Paper

Spontaneous generation and disappearance of burst firing in cultured neuronal network

Man Liu, Wei Zhou, Xiangning Li, Qingming Luo

Proceedings Volume 6534, 65343F (2007) https://doi.org/10.1117/12.741468

KEYWORDS: Neurons, Nervous system, In vitro testing, Signal detection, Photonics, Electrodes, Computer programming, Biomedical optics, Biology, Medicine

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Proceedings Article | 1 May 2007 Paper

Synchronies in cultured neuronal network

Yunsheng Lin, Lin Chen, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6534, 65343D (2007) https://doi.org/10.1117/12.741466

KEYWORDS: Signal processing, Neurons, Brain, Signal detection, Electrodes, In vitro testing, Action potentials, Photonics, Data processing, Binary data

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Proceedings Article | 26 April 2007 Paper

Application of LASCA for study of blood microcirculation in brain: testing of new prophylactic preparations

Sergey Ulyanov, Yulia Ganilova, Onega Ulianova, Pengcheng Li, Dan Zhu, Qingming Luo

Proceedings Volume 6535, 65351B (2007) https://doi.org/10.1117/12.740981

KEYWORDS: Speckle, Brain, Blood, Prototyping, Bacteria, Head, Neuroimaging, Visualization, Microscopes, Spatial resolution

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Proceedings Article | 26 April 2007 Paper

Stratum corneum: a barrier of skin resistants light

Dan Zhu, Yating Hu, Zongzhen Mao, Ying Zheng, Wei Lu, Qingming Luo

Proceedings Volume 6535, 653510 (2007) https://doi.org/10.1117/12.740971

KEYWORDS: Skin, Optical clearing, Tissues, Refractive index, System integration, Tissue optics, In vitro testing, Transmittance, Integrating spheres, Light scattering

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Proceedings Article | 26 April 2007 Paper

Monitor glucose induced changes in optical properties of rat skin in vitro

Dan Zhu, Wei Lu, Qin Li, Hui Gong, Qingming Luo

Proceedings Volume 6535, 65350P (2007) https://doi.org/10.1117/12.740956

KEYWORDS: Skin, Glucose, Tissue optics, Optical properties, Absorption, Optical clearing, Scattering, Optical fibers, In vitro testing, Tissues

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SPIE Journal Paper | 1 March 2007 Open Access

Analysis of the dispersion compensation of acousto-optic deflectors used for multiphoton imaging

Shaoqun Zeng, Xiaohua Lv, Kun Bi, Chen Zhan, Derong Li, Wei Chen, Wenhui Xiong, Steven Jacques, Qingming Luo

JBO, Vol. 12, Issue 02, 024015, (March 2007) https://doi.org/10.1117/12.10.1117/1.2714061

KEYWORDS: Prisms, Bragg cells, Acousto-optics, Adaptive optics, Scanners, Multiphoton microscopy, Biological research, Luminescence, Optical components, Pulsed laser operation

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Proceedings Article | 15 February 2007 Paper

A preliminary study on determining the time window of hypothermia cerebral protection in rat cortex by laser speckle flowmetry

Wenjia Wang, Qiang Li, Shaoqun Zeng, Qingming Luo, Pengcheng Li

Proceedings Volume 6445, 64450Q (2007) https://doi.org/10.1117/12.701609

KEYWORDS: Veins, Arteries, Blood, Cerebral blood flow, Laser speckle imaging, Blood circulation, Speckle, Therapeutics, Laser scattering, Hemodynamics

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Proceedings Article | 15 February 2007 Paper

Elicitation interval dependent spatiotemporal evolution of cortical spreading depression waves revealed by optical intrinsic signal imaging

Shangbin Chen, Hui Gong, Shaoqun Zeng, Qingming Luo, Pengcheng Li

Proceedings Volume 6445, 64450R (2007) https://doi.org/10.1117/12.701699

KEYWORDS: Wave propagation, Reflectivity, Optical imaging, Light wave propagation, Potassium, Blood, Biomedical optics, Tissues, Electrodes, Image acquisition

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Proceedings Article | 13 February 2007 Paper

Design and evaluation of a simultaneous fNIRS/ERP instrument

Li Li, Peng Du, Ting Li, Qingming Luo, Hui Gong

Proceedings Volume 6434, 643429 (2007) https://doi.org/10.1117/12.701730

KEYWORDS: Electrodes, Linear filtering, Tissues, Electroencephalography, Light emitting diodes, Brain, Sensors, Amplifiers, Blood, Near infrared spectroscopy

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Proceedings Article | 13 February 2007 Paper

Optical imaging the redox status change during cell apoptosis

Ting Su, Zhihong Zhang, Juqiang Lin, Qingming Luo

Proceedings Volume 6438, 64380K (2007) https://doi.org/10.1117/12.701654

KEYWORDS: Cell death, Luminescence, Oxygen, Green fluorescent protein, Confocal microscopy, Imaging systems, Proteins, Hydrogen, Optical imaging, In vivo imaging

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Proceedings Article | 7 February 2007 Paper

Influence of refractive index and molecular weight of alcohol agents on skin optical clearing effect

Zhongzhen Mao, Ying Zheng, Yating Hu, Wei Lu, Qingming Luo, Dan Zhu

Proceedings Volume 6436, 64360O (2007) https://doi.org/10.1117/12.701701

KEYWORDS: Optical clearing, Skin, Refractive index, Tissues, Signal attenuation, Biomedical optics, Tissue optics, Scattering, Integrating spheres, Transmittance

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Proceedings Article | 7 February 2007 Paper

Richardson-Lucy deconvolution for two-photon fluorescence images via non-linear diffusion equation pre-filtering

Hongmin Zhang, Zhitao Zhang, Qingming Luo, Shaoqun Zeng

Proceedings Volume 6436, 64360P (2007) https://doi.org/10.1117/12.701750

KEYWORDS: Deconvolution, Point spread functions, Luminescence, Diffusion, Microscopy, Two photon excitation microscopy, Anisotropic diffusion, Image processing, Laser scanners, In vivo imaging

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Proceedings Article | 7 February 2007 Paper

Evaluation the development of focal cerebral ischemia in rats by optical imaging based on the spreading depression signals

Shangbin Chen, Zhe Feng, Shaoqun Zeng, Qingming Luo, Pengcheng Li

Proceedings Volume 6436, 64360A (2007) https://doi.org/10.1117/12.701636

KEYWORDS: Ischemia, Reflectivity, Brain, Optical imaging, Arteries, Spatial resolution, Wave propagation, Neuroimaging, Biomedical optics, Optical resolution

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Proceedings Article | 3 February 2007 Paper

In vivo detecting matrix metalloproteinase (MMP) activity by a genetically engineered fluorescent probe

Jie Yang, Zhihong Zhang, Ting Su, Qingming Luo

Proceedings Volume 6449, 644919 (2007) https://doi.org/10.1117/12.701627

KEYWORDS: Luminescence, Tumors, Content addressable memory, Sensors, Fluorescence resonance energy transfer, Proteins, Signal detection, In vivo imaging, Optical filters, Cancer

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Proceedings Article | 27 October 2006 Paper

A digital rat atlas of sectional anatomy

Li Yu, Qian Liu, Xueling Bai, Yinping Liao, Qingming Luo, Hui Gong

Proceedings Volume 6047, 60470Y (2006) https://doi.org/10.1117/12.710690

KEYWORDS: 3D modeling, 3D image processing, Image processing, Brain, Scanners, Tissues, Computed tomography, Image segmentation, Eye models, Iron

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Proceedings Article | 27 October 2006 Paper

Characteristic of polarized light propagation in turbid media

Yong Deng, Qingming Luo, Qiang Lu

Proceedings Volume 6047, 604705 (2006) https://doi.org/10.1117/12.709767

KEYWORDS: Polarization, Backscatter, Light scattering, Scattering, Linear polarizers, Laser scattering, Photonics, Charge-coupled devices, Tissue optics, Sensors

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Proceedings Article | 27 October 2006 Paper

Monitoring apoptosis of TK-GFP-expressing ACC-M cells induced by ACV using FRET technique

Tao Xiong, Zhihong Zhang, Juqiang Lin, Jie Yang, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6047, 60472J (2006) https://doi.org/10.1117/12.710962

KEYWORDS: Fluorescence resonance energy transfer, Cell death, Tumors, Fluorescent proteins, Green fluorescent protein, Tissues, Proteins, Luminescence, Microscopy, Photonics

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SPIE Journal Paper | 1 September 2006 Open Access

Quantum dot optical encoded polystyrene beads for DNA detection

Yuan-Cheng Cao, Tian-Cai Liu, Xiao-Feng Hua, Xiao-Xia Zhu, Hai-Qiao Wang, Zhen-Li Huang, Yuan-Di Zhao, Man-Xi Liu, Qingming Luo

JBO, Vol. 11, Issue 05, 054025, (September 2006) https://doi.org/10.1117/12.10.1117/1.2358957

KEYWORDS: Target detection, Quantum dots, Biomedical optics, Quantum optics, Luminescence, Computer programming, Signal detection, Biological research, Molecules, Chemical analysis

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Proceedings Article | 24 July 2006 Paper

Interaction of Francisella tularensis bacterial cells with dynamic speckles

Onega Ulianova, Sergey Ulyanov, Elena Sazanova, Irina Zudina, Zhihong Zhang, Zhou Sibo, Qingming Luo

Proceedings Volume 6163, 61631U (2006) https://doi.org/10.1117/12.697433

KEYWORDS: Molecules, Oxygen, Bacteria, Argon, Speckle, Molecular interactions, Laser tissue interaction, Laser therapeutics, Medicine, Laser processing

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Proceedings Article | 24 July 2006 Paper

The optimal source-dector separations for measurements of muscle oxygenation by NIRS

Dan Zhu, Xuan Du, Wei Lu, Dailin Xia, Qingming Luo

Proceedings Volume 6163, 61631C (2006) https://doi.org/10.1117/12.697335

KEYWORDS: Blood, Near infrared spectroscopy, Veins, Oxygen, Tissue optics, Tissues, Ischemia, Sensors, Mode conditioning cables, Modulation

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Proceedings Article | 21 July 2006 Paper

Digital speckle-photography, LASCA and cross-correlation techniques for study of blood microflow in isolated vessel

Yulia Ganilova, Pengcheng Li, Dan Zhu, Nisong Lin, Haiying Chen, Qingming Luo, Sergey Ulyanov

Proceedings Volume 6163, 616319 (2006) https://doi.org/10.1117/12.697332

KEYWORDS: Speckle, Speckle pattern, Scattering, Photography, Blood, Correlation function, Gaussian beams, Diagnostics, CCD cameras, Microscopes

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Proceedings Article | 21 July 2006 Paper

Laser speckle techniques for studying thermally induced dynamics of blood perfusion of mice's mesentery

Dan Zhu, Yang Weng, Ting Zhang, Qian Liu, Qingming Luo

Proceedings Volume 6163, 616302 (2006) https://doi.org/10.1117/12.696925

KEYWORDS: Blood, Speckle, Tumors, Blood circulation, Laser speckle imaging, Microscopy, Temperature metrology, Tissues, Laser systems engineering, Blood vessels

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Proceedings Article | 21 July 2006 Paper

The empiristic theory of photon migrating in local tissue and estimation of the optical properties from reflectance measurement

Qin Li, Dan Zhu, Wei Lu, Qingming Luo, Hui Gong

Proceedings Volume 6163, 61631B (2006) https://doi.org/10.1117/12.697334

KEYWORDS: Tissue optics, Optical properties, Reflectivity, Monte Carlo methods, Scattering, Tissues, Optical testing, Light scattering, Light, Anisotropy

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SPIE Journal Paper | 1 July 2006 Open Access

Real-time detection of caspase-2 activation in a single living HeLa cell during cisplatin-induced apoptosis

Juqiang Lin, Zhihong Zhang, Jie Yang, Shaoqun Zeng, Bifeng Liu, Qingming Luo

JBO, Vol. 11, Issue 02, 024011, (July 2006) https://doi.org/10.1117/12.10.1117/1.2187013

KEYWORDS: Fluorescence resonance energy transfer, Cell death, Proteins, Fluorescent proteins, In vitro testing, Luminescence, Spectroscopy, Imaging systems, Bacteria, Biomedical optics

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SPIE Journal Paper | 1 July 2006 Open Access

Errata: Real-time detection of caspase-2 activation in a single living HeLa cell during cisplatin-induced apoptosis

Juqiang Lin, Zhihong Zhang, Shaoqun Zeng, Bifeng Liu, Qingming Luo, Jie Yang

JBO, Vol. 11, Issue 04, 049801, (July 2006) https://doi.org/10.1117/12.10.1117/1.2219117

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Proceedings Article | 14 June 2006 Paper

Computer simulation of the processes of inactivation of bacterial cells by dynamic low-coherent speckles

Onega Ulianova, Sergey Ulyanov, Elena Sazanova, Zhang Zhihong, Zhou Sibo, Qingming Luo, Irina Zudina, Andrey Bednov

Proceedings Volume 6254, 62541K (2006) https://doi.org/10.1117/12.679956

KEYWORDS: Oxygen, Molecules, Bacteria, Argon, Molecular interactions, Ions, Computer simulations, Radiation effects, Speckle, Laser therapeutics

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Proceedings Article | 19 May 2006 Paper

Monitoring apoptosis of TK-GFP-expressing ACC-M cells induced by ACV using FRET technique

Tao Xiong, Zhihong Zhang, Juqiang Lin, Jie Yang, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6218, 62180L (2006) https://doi.org/10.1117/12.662591

KEYWORDS: Fluorescence resonance energy transfer, Cell death, Tumors, Green fluorescent protein, Fluorescent proteins, Tissues, Proteins, Luminescence, Microscopy, Cell mechanics

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SPIE Journal Paper | 1 May 2006 Open Access

In vivo optical reflectance imaging of spreading depression waves in rat brain with and without focal cerebral ischemia

Shangbin Chen, Zhe Feng, Pengcheng Li, Steven Jacques, Shaoqun Zeng, Qingming Luo

JBO, Vol. 11, Issue 03, 034002, (May 2006) https://doi.org/10.1117/12.10.1117/1.2203654

KEYWORDS: Reflectivity, Brain, Neuroimaging, Blood, Optical imaging, Ischemia, Arteries, Skull, In vivo imaging, Biomedical optics

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Proceedings Article | 3 March 2006 Paper

Analysis of synchrony in cultured neuronal network

Yunsheng Lin, Lin Chen, Wei Zhou, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6085, 60850H (2006) https://doi.org/10.1117/12.647187

KEYWORDS: Neurons, Signal processing, Signal detection, Brain, Electrodes, In vitro testing, Action potentials, Biomedical optics, Photonics, In vivo imaging

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Proceedings Article | 3 March 2006 Paper

Inactivation of bacteria of P. Aeruginosa by coherent and low-coherent speckles: Cellular response on photodamages

Onega Ulianova, Zhou Sibo, Zhang Zhihong, Sergey Ulyanov, Qingming Luo

Proceedings Volume 6085, 60850A (2006) https://doi.org/10.1117/12.656268

KEYWORDS: Bacteria, Speckle, Mathematical modeling, Oxygen, Biomedical optics, Computer simulations, Low-intensity laser therapy, Laser tissue interaction, Photonics, Laser irradiation

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Proceedings Article | 3 March 2006 Paper

Responses of cultured neuronal network to different electrical stimuli patterns

Lin Chen, Chuanping Chen, Yunsheng Lin, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6085, 60850G (2006) https://doi.org/10.1117/12.647176

KEYWORDS: Neurons, Electrodes, Modulation, Data acquisition, Biomedical optics, Photonics, In vitro testing, Electrophysiology, Microelectronics, Network security

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Proceedings Article | 3 March 2006 Paper

Combine temporal clustering analysis with least square estimation to determine the dynamic pattern of cortical spreading depression

Shangbin Chen, Pengcheng Li, Hui Gong, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6085, 60850D (2006) https://doi.org/10.1117/12.644125

KEYWORDS: Wave propagation, Binary data, Optical imaging, Functional magnetic resonance imaging, Image analysis, Reflectivity, Blood, Statistical analysis, Lead, Biomedical optics

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Proceedings Article | 3 March 2006 Paper

Frame self-division applied in analysis of intrinsic signal optical imaging data

Weihua Luo, Pengcheng Li, Li Zhang, Xiaohua Lv, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6085, 60850E (2006) https://doi.org/10.1117/12.645570

KEYWORDS: Optical imaging, Interference (communication), Signal to noise ratio, Image processing, Data processing, Biomedical optics, Signal analyzers, Photonics, Data analysis, Light

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Proceedings Article | 22 February 2006 Paper

Glutamate-induced intracellular calcium oscillations in astrocytes with confocal microscopy

Yuan Zhang, Wei Zhou, Xiuli Liu, Geng Zhu, Yuxiang Wu, Qingming Luo

Proceedings Volume 6088, 60881I (2006) https://doi.org/10.1117/12.647055

KEYWORDS: Calcium, Confocal microscopy, Luminescence, Glia, Receptors, Neurons, Brain, Tissues, Modulation, Neurotransmitters

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Proceedings Article | 22 February 2006 Paper

Application of a FRET probe for Caspase-3 activation in living HeLa cells by sequentially treated cisplatin and TRAIL

Juqiang Lin, Zhihong Zhang, Qiushi Yi, Shaoqun Zeng, Qingming Luo

Proceedings Volume 6088, 60881K (2006) https://doi.org/10.1117/12.647151

KEYWORDS: Fluorescence resonance energy transfer, Cell death, Proteins, Tumors, Cancer, Luminescence, Fluorescent proteins, Imaging systems, Resonance enhancement, Tissues

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Proceedings Article | 22 February 2006 Paper

Application of confocal microscopy on glutamate-induced intracellular calcium transient in neurons

Geng Zhu, Wei Zhou, Yuan Zhang, Xiuli Liu, Yuxiang Wu, Qingming Luo

Proceedings Volume 6088, 60881J (2006) https://doi.org/10.1117/12.647145

KEYWORDS: Calcium, Neurons, Confocal microscopy, Luminescence, Tissues, Brain, Argon ion lasers, Image analysis, Mode conditioning cables, Fetus

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Proceedings Article | 22 February 2006 Paper

Study of the left prefrontal cortex activity of Chinese children with dyslexia in phonological processing by NIRS

Zhili Zhang, Ting Li, Yi Zheng, Qingming Luo, Ranran Song, Hui Gong

Proceedings Volume 6078, 607833 (2006) https://doi.org/10.1117/12.648771

KEYWORDS: Near infrared spectroscopy, Prefrontal cortex, Hemodynamics, Positron emission tomography, Brain, Functional magnetic resonance imaging, Neuroimaging, Light emitting diodes, Tissues, Cerium

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Proceedings Article | 2 February 2006 Paper

Synthesis and properties of quantum dots optical probes for bio-imaging

Tian-Cai Liu, Zhen-Li Huang, Hai-Qiao Wang, Yuan-Di Zhao, Qing-Ming Luo

Proceedings Volume 6026, 60261I (2006) https://doi.org/10.1117/12.667678

KEYWORDS: Quantum dots, Luminescence, Semiconductors, Zinc, Nanoparticles, Biomedical optics, Quantum optics, Nanocrystals, Quantum efficiency, Optical properties

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Proceedings Article | 2 February 2006 Paper

Quantitative doping of commercial polystyrene microbeads with quantum dots

Hai-Qiao Wang, Zhen-Li Huang, Tian-Cai Liu, Jian-Hao Wang, Yuan-Di Zhao, Qing-Ming Luo

Proceedings Volume 6026, 60261J (2006) https://doi.org/10.1117/12.667679

KEYWORDS: Doping, Quantum dots, Luminescence, Computer programming, Imaging spectroscopy, Absorption, Microscopes, Absorbance, Spectroscopy, Nanocrystals

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Proceedings Article | 2 February 2006 Paper

Monitoring thermally induced blood flow change of rat mesentery by laser speckle imaging

Weng Yang, Dan Zhu, Qian Liu, Qingming Luo

Proceedings Volume 6026, 60260B (2006) https://doi.org/10.1117/12.667105

KEYWORDS: Blood circulation, Blood, Velocity measurements, Speckle, Tissues, Laser speckle imaging, Blood vessels, Resistance, Image analysis, Image resolution

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Proceedings Article | 2 February 2006 Paper

Generalized diffusion approximation for highly absorbing media and small source-detector separations

Dan Zhu, Guiling Wu, Qingming Luo, Hui Gong

Proceedings Volume 6026, 602608 (2006) https://doi.org/10.1117/12.667101

KEYWORDS: Diffusion, Scattering, Monte Carlo methods, Photons, Collimation, Anisotropy, Tissues, Sensors, Absorption, Light scattering

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Proceedings Article | 2 February 2006 Paper

Real-time detecting gelatinases activity in living cells by FRET imaging

Jie Yang, Zhihong Zhang, Bifeng Liu, Qingming Luo

Proceedings Volume 6026, 60260U (2006) https://doi.org/10.1117/12.667180

KEYWORDS: Fluorescence resonance energy transfer, Luminescence, Proteins, Tumors, Cancer, Signal detection, Fluorescence spectroscopy, Confocal microscopy, Fusion energy, Molecules

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Proceedings Article | 2 February 2006 Paper

Hemodynamic responses to functional activation accessed by optical imaging

Songlin Ni, Pengcheng Li, Yuanyuan Yang, Xiaohua Lv, Qingming Luo

Proceedings Volume 6026, 602607 (2006) https://doi.org/10.1117/12.667100

KEYWORDS: Blood circulation, Speckle, Imaging spectroscopy, Spectroscopy, Light emitting diodes, Optical imaging, Laser speckle contrast imaging, Hemodynamics, Imaging systems, Laser speckle imaging

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Proceedings Article | 2 February 2006 Paper

Imaging of caspase-3 activation by a novel FRET probe composed of CFP and DsRed

Juquiang Lin, Zhihong Zhang, Bifeng Liu, Qingming Luo

Proceedings Volume 6026, 60260V (2006) https://doi.org/10.1117/12.667181

KEYWORDS: Fluorescence resonance energy transfer, Cell death, Fluorescent proteins, Proteins, Luminescence, In vivo imaging, Chromium, Resonance enhancement, Tumors, Cancer

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Proceedings Article | 22 June 2005 Paper

Inactivation of bacterial cells by dynamic low-coherent speckles: mathematical model of photoprocessing

Onega Ulianova, Sergey Ulyanov, Elena Sazanova, Zhihong Zhang, Sibo Zhou, Qingming Luo, Irina Zudina, Andrey Bednov

Proceedings Volume 5771, (2005) https://doi.org/10.1117/12.634847

KEYWORDS: Bacteria, Oxygen, Mathematical modeling, Molecules, Speckle, Computer simulations, Laser processing, Medicine, Microorganisms, Biomedical optics

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Proceedings Article | 28 April 2005 Paper

Float genetic algorithm for determination of particle size distribution and refractive index in polarized LSS

Yong Deng, Rui Hu, Qingming Luo, Qiang Lu

Proceedings Volume 5693, (2005) https://doi.org/10.1117/12.589583

KEYWORDS: Refractive index, Particles, Genetic algorithms, Error analysis, Light scattering, Tissues, Spectroscopy, Scattering, Mie scattering, Inverse problems

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Proceedings Article | 28 April 2005 Paper

Wireless noninvasive optical oxygen monitor based on GPRS

Gang Chen, Xuan Du, Guodong Xu, Qingming Luo

Proceedings Volume 5693, (2005) https://doi.org/10.1117/12.590479

KEYWORDS: Oxygen, Blood, General packet radio service, Tissue optics, Tissues, Sensors, Data communications, Internet, Near infrared spectroscopy, Near infrared

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Proceedings Article | 31 March 2005 Paper

Monitoring calcium concentration in dendritic spines of cultured hippocampal neurons with cameleons

Xiuli Liu, Wei Zhou, Xiangning Li, Hui Gong, Qingming Luo

Proceedings Volume 5703, (2005) https://doi.org/10.1117/12.592075

KEYWORDS: Calcium, Spine, Neurons, Fluorescence resonance energy transfer, Luminescence, Dendrites, Synaptic plasticity, Confocal microscopy, Molecules, Diffusion

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Proceedings Article | 29 March 2005 Paper

Temporal dynamics of blood microcirculation in oral cavity mucous membrane caused by low-intensity laser irradiation

Sergey Ulyanov, Haiying Chen, Natalia Kharish, Alexander Lepilin, Nisong Lin, Qingming Luo, Mikhail Naumov, Liu Qian, Elena Safonkina, Alexey Sedykh, Onega Ulianova, Weng Yang, Dan Zhu

Proceedings Volume 5696, (2005) https://doi.org/10.1117/12.596957

KEYWORDS: Blood, Doppler effect, Laser therapeutics, Laser irradiation, Diagnostics, Light scattering, Laser dentistry, Laser speckle imaging, Capillaries, Photoplethysmography

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Proceedings Article | 29 March 2005 Paper

FRAP data processing with three-exponential fitting method

Ting Li, Wei Zhou, Qingming Luo

Proceedings Volume 5696, (2005) https://doi.org/10.1117/12.590229

KEYWORDS: Luminescence, Data modeling, Mathematical modeling, Proteins, Molecules, Diffusion, Data processing, Biomedical optics, Biology, 3D modeling

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Proceedings Article | 29 March 2005 Paper

Using threshold segmentation methods to measure dynamic vasodilatation in a series of optical images

Shangbin Chen, Pengcheng Li, Shaoqun Zeng, Qingming Luo

Proceedings Volume 5696, (2005) https://doi.org/10.1117/12.589795

KEYWORDS: Image segmentation, Arteries, Hemodynamics, Algorithm development, Intrinsic optical signal imaging, Optical imaging, Blood, Stars, Image processing, Biomedical optics

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Proceedings Article | 29 March 2005 Paper

Enhancement of synaptic transmission induced by BDNF in cultured cortical neurons

Jun He, Hui Gong, Shaoqun Zeng, Yanling Li, Qingming Luo

Proceedings Volume 5696, (2005) https://doi.org/10.1117/12.592072

KEYWORDS: Calcium, Neurons, Synaptic transmission, Receptors, Sodium, Cadmium, Synaptic plasticity, Luminescence, Action potentials, Photonics

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Proceedings Article | 29 March 2005 Paper

Verbal working memory load affects prefrontal cortices activation: evidence from a functional NIRS study in humans

Chengjun Li, Hui Gong, Shaoqun Zeng, Qingming Luo

Proceedings Volume 5696, (2005) https://doi.org/10.1117/12.590222

KEYWORDS: Near infrared spectroscopy, Hemodynamics, Imaging systems, Positron emission tomography, Prefrontal cortex, Brain, Neuroimaging, Functional magnetic resonance imaging, Light emitting diodes, Sensors

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Proceedings Article | 29 March 2005 Paper

Flux balance analysis of myocardial mitochondrial metabolic network

Ruoyu Luo, Sha Liao, Bifeng Liu, Manxi Liu, Hongming Zhang, Qingming Luo

Proceedings Volume 5696, (2005) https://doi.org/10.1117/12.589567

KEYWORDS: Acquisition tracking and pointing, Biological research, Glucose, Oxygen, Complex systems, Mode conditioning cables, Systems modeling, Integration, Organisms, Bioinformatics

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Proceedings Article | 29 March 2005 Paper

In vivo optical imaging of bacterial infection and antibiotic response in intact nude mice

Tao Xiong, Yanping Chen, Jun Chu, Zhihong Zhang, Bifeng Liu, Qingming Luo

Proceedings Volume 5699, (2005) https://doi.org/10.1117/12.592770

KEYWORDS: Bacteria, Luminescence, Whole body imaging, Green fluorescent protein, In vivo imaging, Digital cameras, Abdomen, Visualization, Tumors, Optical imaging

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SPIE Journal Paper | 1 March 2005 Open Access

Temporal clustering analysis of cerebral blood flow activation maps measured by laser speckle contrast imaging

Qian Liu, Zheng Wang, Qingming Luo

JBO, Vol. 10, Issue 02, 024019, (March 2005) https://doi.org/10.1117/12.10.1117/1.1891105

KEYWORDS: Laser speckle contrast imaging, Brain, Speckle, Functional magnetic resonance imaging, Nerve, Cerebral blood flow, Blood circulation, Brain mapping, Somatosensory cortex, Blood

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Proceedings Article | 18 January 2005 Paper

Changes in hemodynamics and light scattering during cortical spreading depression

Pengcheng Li, Yuanyuan Yang, Qingming Luo

Proceedings Volume 5630, (2005) https://doi.org/10.1117/12.580655

KEYWORDS: Light scattering, Reflectivity, Intrinsic optical signal, Signal detection, Information operations, Hemodynamics, Scattering, Brain, Optical imaging, Spectroscopy

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Proceedings Article | 18 January 2005 Paper

Fluorescence correlation spectroscopy considering the effect of photobleaching

Yafeng Liu, Tongsheng Chen, Qingming Luo, Shaoqun Zeng

Proceedings Volume 5630, (2005) https://doi.org/10.1117/12.580645

KEYWORDS: Molecules, Luminescence, Fluorescence correlation spectroscopy, Diffusion, Biomedical optics, Sensors, Molecular spectroscopy, Tissue optics, Signal to noise ratio, Time metrology

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Proceedings Article | 18 January 2005 Paper

Monitoring of prefrontal cortex activation during verbal n-back task with 24-channel functional NIRS imager

Chengjun Li, Hui Gong, Zhuo Gan, Qingming Luo

Proceedings Volume 5630, (2005) https://doi.org/10.1117/12.580575

KEYWORDS: Near infrared spectroscopy, Imaging systems, Hemodynamics, Prefrontal cortex, Brain, Positron emission tomography, Cognitive modeling, Neuroimaging, Light emitting diodes, Biomedical optics

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Proceedings Article | 18 January 2005 Paper

Laser speckle contrast imaging: monitoring blood flow dynamics and vascular structure of photodynamic therapy

Qian Liu, Sibo Zhou, Zhihong Zhang, Qingming Luo

Proceedings Volume 5630, (2005) https://doi.org/10.1117/12.572202

KEYWORDS: Speckle, Photodynamic therapy, Laser speckle contrast imaging, Blood circulation, Content addressable memory, In vivo imaging, Blood, Tumors, Speckle pattern, CCD cameras

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Proceedings Article | 18 January 2005 Paper

Compact whole-body fluorescent imaging of nude mice bearing EGFP expressing tumor

Yanping Chen, Tao Xiong, Jun Chu, Li Yu, Shaoqun Zeng, Qingming Luo

Proceedings Volume 5630, (2005) https://doi.org/10.1117/12.580663

KEYWORDS: Tumors, Luminescence, Green fluorescent protein, Lung, Lamps, In vivo imaging, Mercury, Optical imaging, Visualization, Fluorescent proteins

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Proceedings Article | 18 January 2005 Paper

Thermally-induced effects on normal and tumor of mouse mesentery based on measuring microcirculation parameters and temperature

Dan Zhu, Qingming Luo, Ting Zhang

Proceedings Volume 5630, (2005) https://doi.org/10.1117/12.580797

KEYWORDS: Tumors, Tissues, Blood, Blood circulation, Temperature metrology, Thermal effects, Blood vessels, Speckle, Heat therapy, Video

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Proceedings Article | 20 August 2004 Paper

Speckle method for monitoring of blood microflow

Yulia Ganilova, Haiying Cheng, Sergey Ulyanov, Qingming Luo

Proceedings Volume 5474, (2004) https://doi.org/10.1117/12.578983

KEYWORDS: Speckle, Gaussian beams, Image quality, Blood, Convolution, Speckle pattern, Blood circulation, Beam analyzers, Geometrical optics, Microscopy

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Proceedings Article | 20 August 2004 Paper

Monte Carlo simulation of polarization backscattering spectroscopy

Yong Deng, Qiang Lu, Qingming Luo, Rui Hu, Dan Zhu

Proceedings Volume 5474, (2004) https://doi.org/10.1117/12.578937

KEYWORDS: Monte Carlo methods, Scattering, Light scattering, Polarization, Spectroscopy, Mie scattering, Tissue optics, Backscatter, Particles, Algorithm development

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SPIE Journal Paper | 1 July 2004 Open Access

Redox ratio of mitochondria as an indicator for the response of photodynamic therapy

Zhihong Zhang, Dana Blessington, Hui Li, Theresa Busch, Jerry Glickson, Qingming Luo, Britton Chance, Gang Zheng

JBO, Vol. 9, Issue 04, (July 2004) https://doi.org/10.1117/12.10.1117/1.1760759

KEYWORDS: Tumors, Photodynamic therapy, Luminescence, Control systems, Flavoproteins, Oxygen, Tissues, Photography, Radiology, Tissue optics

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Proceedings Article | 28 May 2004 Paper

Temporal clustering analysis of cerebral blood flow activation maps measured by laser speckle contrast imaging

Zheng Wang, Qingming Luo

Proceedings Volume 5330, (2004) https://doi.org/10.1117/12.535380

KEYWORDS: Laser speckle contrast imaging, Brain, Functional magnetic resonance imaging, Nerve, Cerebral blood flow, Speckle, Blood circulation, Somatosensory cortex, Spatial resolution, Brain mapping

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