Prof. Shunichi Sato Profile

Prof. Shunichi Sato

Professor at National Defense Medical College

SPIE Involvement:

Conference Program Committee | Author

Publications (155)

Proceedings Article | 13 March 2024 Presentation + Paper

Femtosecond laser-processed biodegradable porous membranes for cultivation and transplantation of three-dimensional skin substitutes

Yasuyuki Tsunoi, Izumi Takayama, Naonari Kondo, Yo Nagano, Hiromi Miyazaki, Taiichiro Ida, Mitsuru Akashi, Mitsuhiro Terakawa, Shunichi Sato

Proceedings Volume 12816, 1281609 (2024) https://doi.org/10.1117/12.2688299

KEYWORDS: Skin, Tissues, Porosity, 3D modeling, Transplantation, Femtosecond phenomena, Polymers, Defense and security, Blood vessels, Laser processing

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Proceedings Article | 12 March 2024 Presentation + Paper

Transvascular delivery of cisplatin to subcutaneous tumors in mice by photomechanical waves

Yasuyuki Tsunoi, Hitoshi Tsuda, Koji Araki, Shunichi Sato

Proceedings Volume 12840, 1284007 (2024) https://doi.org/10.1117/12.3000426

KEYWORDS: Tumors, Pulsed laser operation, Tissues, Animal model studies, Cancer, Plasma, Chemotherapy

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SPIE Journal Paper | 15 February 2024 Open Access

In vivo visualization of burn depth in skin tissue of rats using hemoglobin parameters estimated by diffuse reflectance spectral imaging

Md. Anowar Parvez, Kazuhiro Yashiro, Yuki Nagahama, Yasuyuki Tsunoi, Daizoh Saitoh, Shunichi Sato, Izumi Nishidate

JBO, Vol. 29, Issue 02, 026003, (February 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.2.026003

KEYWORDS: Skin, Injuries, Tissues, Image classification, Visualization, Absorbance, In vivo imaging, Diffuse reflectance spectroscopy, Oxygen, Imaging spectroscopy

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SignificanceBurn injuries represent a global public health problem that kills an estimated 180,000 people annually. Non-fatal burns result in prolonged hospitalization, disfigurement, and disability. The most common, convenient, and widely used method for assessing burn depth is physical or visual examination, but the accuracy of this method is reportedly poor (60% to 75%). Rapid, correct assessment of burn depth is very important for the optimal management and treatment of burn patients. New methods of burn depth assessment that are inexpensive, simple, rapid, non-contact, and non-invasive are therefore needed.AimThe aim of this study was to propose an approach to visualize the spatial distribution of burn depth using hemoglobin parameters estimated from spectral diffuse reflectance imaging and to demonstrate the feasibility of the proposed approach for differentiating burn depth in a rat model of scald burn injury.ApproachThe new approach to creating a spatial map of burn depth was based on canonical discriminant analysis (CDA) of total hemoglobin concentration, tissue oxygen saturation, and methemoglobin saturation as estimated from spectral diffuse reflectance images. Burns of three different degrees of severity were created in rat dorsal skin by 10-s exposure to water maintained at 70°C, 78°C, and 98°C, respectively. Spectral images for dorsal regions were acquired under anesthesia immediately after burn injury and at 24 h, 48 h, and 72 h after injury.ResultsMost areas of images in the group with skin exposed to 70°C water and 98°C water were classified as 70°C burn and 98°C burn, respectively. In contrast, no significant difference between areas classified as 78°C burn and 98°C burn from 24 h to 72 h was evident in the group with skin exposed to 78°C water, suggesting that burn depth was heterogeneous.ConclusionsThe proposed approach combining diffuse reflectance spectral imaging and CDA appears promising for differentiating 70°C burns from 78°C burns and 98°C burns, and 98°C burns from 70°C burns and 78°C burns at 24 to 72 h after burn injury in a rat model of scald burn injury.

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Proceedings Article | 20 September 2023 Paper

In vivo monitoring of hemoglobin derivative concentrations and saturations in rat burn wounds using a red-green-blue camera

Md Anowar Parvez, Kaisei Okura, Kazuhiro Yashiro, Yasuyuki Tsunoi, Daizoh Saitoh, Shunichi Sato, Izumi Nishidate

Proceedings Volume 12608, 1260815 (2023) https://doi.org/10.1117/12.3007929

KEYWORDS: Skin, Cameras, Tissues, Matrices, Injuries, In vivo imaging, RGB color model, Hemodynamics, Oxygen, Monte Carlo methods

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Proceedings Article | 11 August 2023 Paper

Control of the viability of three-dimensional cultured skins by photobiomodulation

Yasuyuki Tsunoi, Hiromi Miyazaki, Satoko Kawauchi, Daizoh Saitoh, Mitsuru Akashi, Shunichi Sato

Proceedings Volume 12627, 1262724 (2023) https://doi.org/10.1117/12.2668239

KEYWORDS: Skin, Light emitting diodes, Tissues, Defense and security, Medical research, Injuries, 3D modeling

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Proceedings Article | 22 May 2023 Presentation + Paper

In vivo transcutaneous monitoring of hemoglobin derivatives in thermally damaged skin tissue of rats using hyperspectral diffuse reflectance imaging

Md. Anowar Parvez, Kazuhiro Yashiro, Izumi Nishidate, Yasuyuki Tsunoi, Yasue Haruyama, Daizoh Saitoh, Shunichi Sato

Proceedings Volume 12327, 123270H (2023) https://doi.org/10.1117/12.2644804

KEYWORDS: Skin, Tissues, Injuries, Diffuse reflectance spectroscopy, Oxygen, Oxygenation, Hyperspectral imaging, In vivo imaging, Imaging spectroscopy, Cameras

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SPIE Journal Paper | 27 January 2022 Open Access

Depth distributions of bacteria for the Pseudomonas aeruginosa-infected burn wounds treated by methylene blue-mediated photodynamic therapy in rats: effects of additives to photosensitizer

Roma Rani Sarker, Yasuyuki Tsunoi, Yasue Haruyama, Shunichi Sato, Izumi Nishidate

JBO, Vol. 27, Issue 01, 018001, (January 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.1.018001

KEYWORDS: Bacteria, Tissues, Picosecond phenomena, Bioalcohols, Skin, Oxygen, Natural surfaces, Image segmentation, Toxicity, Photodynamic therapy

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Proceedings Article | 5 March 2021 Presentation + Paper

Antimicrobial photodynamic therapy for burn wound infection with P. aeruginosa in rats

Roma Rani Sarker, Yasuyuki Tsunoi, Yasue Haruyama, Shunichi Sato, Izumi Nishidate

Proceedings Volume 11626, 116260Q (2021) https://doi.org/10.1117/12.2578087

KEYWORDS: Bacteria, Photodynamic therapy, Tissues, Light emitting diodes, In vivo imaging, Bioalcohols

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Proceedings Article | 9 March 2020 Presentation

In vivo imaging of shock wave-induced nitric oxide generation in the rat cortex (Conference Presentation)

Masaki Inaba, Satoko Kawauchi, Takeshi Adachi, Shunichi Sato, Izumi Nishidate

Proceedings Volume 11225, 1122504 (2020) https://doi.org/10.1117/12.2545452

KEYWORDS: In vivo imaging, NOx, Luminescence, Brain, Traumatic brain injury, Blood vessels, Hemodynamics, Visualization, Cranial windows, Bone

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SPIE Journal Paper | 8 March 2019 Open Access

Multispectral imaging of cortical vascular and hemodynamic responses to a shock wave: observation of spreading depolarization and oxygen supply-demand mismatch

Satoko Kawauchi, Wataru Okuda, Hiroshi Nawashiro, Shunichi Sato, Izumi Nishidate

JBO, Vol. 24, Issue 03, 035005, (March 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.3.035005

KEYWORDS: Oxygen, Multispectral imaging, Hemodynamics, Brain, Tissues, Scattering, Light scattering, Reflectivity, Wave propagation, Absorption

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Proceedings Article | 4 March 2019 Presentation

Imaging of cerebral hemodynamic and light scattering responses to somatosensory electrical stimulation using a digital RGB color camera (Conference Presentation)

Izumi Nishidate, Takayuki Tsubonuma, Masaki Inaba, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yasuaki Kokubo

Proceedings Volume 10864, 108640D (2019) https://doi.org/10.1117/12.2509821

KEYWORDS: Light scattering, RGB color model, Cameras, Hemodynamics, Digital cameras, Scattering, Digital color imaging, Brain, Tissues, Oxygen

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Proceedings Article | 1 March 2019 Paper

Study on the cellular and molecular responses to a shock wave in the rat brain

Masaki Inaba, Satoko Kawauchi, Takeshi Adachi, Shunichi Sato, Izumi Nishidate

Proceedings Volume 10865, 108651C (2019) https://doi.org/10.1117/12.2509235

KEYWORDS: Brain, Hemodynamics, Calcium, Diffuse reflectance spectroscopy, Pulsed laser operation, Defense and security, Improvised explosive devices, Traumatic brain injury, NOx, Plasma

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Proceedings Article | 26 February 2019 Paper

Noninvasive assessment of light scattering and hemoglobin in cutaneous two-stage chemical carcinogenesis of mice based on multispectral diffuse reflectance images

Md Abdul Wares, Naoki Tobita, Masaki Inaba, Satoko Kawauchi, Shunichi Sato, Izumi Nishidate

Proceedings Volume 10851, 1085113 (2019) https://doi.org/10.1117/12.2509793

KEYWORDS: Skin, Tissues, Diffuse reflectance spectroscopy, Light scattering, Oxygen, Scattering, Multispectral imaging, Cancer, Tissue optics, Skin cancer

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SPIE Journal Paper | 11 January 2019 Open Access

Noninvasive evaluation of hemodynamics and light scattering property during two-stage mouse cutaneous carcinogenesis based on multispectral diffuse reflectance images at isosbestic wavelengths of hemoglobin

Md. Abdul Wares, Naoki Tobita, Satoko Kawauchi, Shunichi Sato, Izumi Nishidate

JBO, Vol. 24, Issue 03, 031020, (January 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.3.031020

KEYWORDS: Skin, Scattering, Light scattering, Tissues, Diffuse reflectance spectroscopy, Skin cancer, Tumors, Hemodynamics, Multispectral imaging, Tissue optics

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Proceedings Article | 3 January 2019 Paper

Computer simulation of electric energy distribution of CO gas mixture

Ryo Ochiai, Manabu Taniwaki, Shinnichi Sato, Mitsuhiro Iyoda

Proceedings Volume 11042, 110420B (2019) https://doi.org/10.1117/12.2518869

KEYWORDS: Carbon monoxide, Computer simulations, Gas lasers, Personal digital assistants, Laser development, High power lasers, Optical simulations, Defense technologies, Defense and security, Medical research

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Proceedings Article | 5 November 2018 Paper

RGB camera-based functional imaging of in vivo biological tissues

Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yoshihisa Aizu, Yasuaki Kokubo

Proceedings Volume 10815, 108150S (2018) https://doi.org/10.1117/12.2513306

KEYWORDS: Tissues, Scattering, RGB color model, Light scattering, Brain, Cameras, Oxygen, In vivo imaging, Absorption, Hemodynamics

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Proceedings Article | 24 April 2018 Paper

Effects of nitric oxide on cortical hemodynamic responses in the rat brain exposed to a shock wave

Masaki Inaba, Satoko Kawauchi, Takeshi Adachi, Shunichi Sato, Izumi Nishidate

Proceedings Volume 10711, 107111I (2018) https://doi.org/10.1117/12.2319359

KEYWORDS: Brain, Hemodynamics, Diffuse reflectance spectroscopy, Optical fibers, Pathophysiology, Traumatic brain injury, Improvised explosive devices, Skull, Nitric oxide

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Proceedings Article | 24 April 2018 Paper

Enhanced therapeutic effect of an antitumor agent on malignant glioma in rats by photomechanical wave-based transvascular drug delivery

Yumiko Koshi, Yasuyuki Tsunoi, Arata Tomiyama, Satoko Kawauchi, Kentaro Mori, Shunichi Sato, Izumi Nishidate

Proceedings Volume 10711, 1071111 (2018) https://doi.org/10.1117/12.2319269

KEYWORDS: Tumors, Brain, Pulsed laser operation, Blood brain barrier, Tissues

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Proceedings Article | 24 April 2018 Paper

Noninvasive estimation of light scattering and hemoglobin concentration in mice cutaneous carcinogenesis through multispectral imaging

Md. Abdul Wares, Naoki Tobita, Izumi Nishidate, Satoko Kawauchi, Shunichi Sato

Proceedings Volume 10711, 107110W (2018) https://doi.org/10.1117/12.2317410

KEYWORDS: Skin, Scattering, Light scattering, Skin cancer, Multispectral imaging, Cancer, Tissue optics, Neodymium, Chromophores, Diffuse reflectance spectroscopy

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Proceedings Article | 8 February 2018 Paper

In vivo imaging of cerebral hemodynamics and tissue scattering in rat brain using a surgical microscope camera system

Izumi Nishidate, Takuya Kanie, Afrina Mustari, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yasuaki Kokubo

Proceedings Volume 10480, 104800M (2018) https://doi.org/10.1117/12.2290488

KEYWORDS: Tissues, Scattering, Brain, Light scattering, Oxygen, Hemodynamics, RGB color model, Cameras, In vivo imaging, Neuroimaging

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Proceedings Article | 18 April 2017 Paper

In vivo imaging of spontaneous low-frequency oscillations in cerebral hemodynamics with a digital red-green-blue camera

Afrina Mustari, Naoki Nakamura, Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yasuaki Kokobo

Proceedings Volume 10251, 102510X (2017) https://doi.org/10.1117/12.2273613

KEYWORDS: Brain, Tissues, Cerebral cortex, Mode conditioning cables, Hemodynamics, Cameras, In vivo imaging, Digital cameras, RGB color model, Monte Carlo methods, Diffuse reflectance spectroscopy

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Proceedings Article | 17 February 2017 Paper

Rat brain imaging using full field optical coherence microscopy with short multimode fiber probe

Manabu Sato, Daisuke Saito, Reiko Kurotani, Hiroyuki Abe, Satoko Kawauchi, Shunichi Sato, Izumi Nishidate

Proceedings Volume 10053, 1005338 (2017) https://doi.org/10.1117/12.2250233

KEYWORDS: Multimode fibers, Brain, Optical coherence microscopy, Optical coherence tomography, Neuroimaging, 3D image processing, GRIN lenses, Dispersion, Glasses, Refractive index

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Proceedings Article | 8 February 2017 Paper

Evaluation of spontaneous low-frequency oscillations in cerebral hemodynamics with time-series red-green-blue images

Izumi Nishidate, Afrina Mustari, Naoki Nakamura, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yasuaki Kokubo

Proceedings Volume 10050, 100500Q (2017) https://doi.org/10.1117/12.2253512

KEYWORDS: Brain, Hemodynamics, RGB color model, Blood circulation, Traumatic brain injury, Tissues, Monte Carlo methods, Cerebral cortex, Neuroimaging, Blood, Scattering

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Proceedings Article | 8 February 2017 Presentation + Paper

In vivo imaging of tissue scattering parameter and cerebral hemodynamics in rat brain with a digital red-green-blue camera

Izumi Nishidate, Afrina Mustari, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yasuaki Kokubo

Proceedings Volume 10050, 100500O (2017) https://doi.org/10.1117/12.2251109

KEYWORDS: Scattering, Brain, Cameras, Tissues, Digital cameras, RGB color model, Oxygen, In vivo imaging, Neuroimaging, Monte Carlo methods, Light scattering, Hemodynamics

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Proceedings Article | 16 January 2017 Paper

Computer simulation of effect of conditions on discharge-excited high power gas flow CO laser

Ryo Ochiai, Mitsuhiro Iyoda, Manabu Taniwaki, Shunichi Sato

Proceedings Volume 10254, 102540V (2017) https://doi.org/10.1117/12.2254956

KEYWORDS: Lasers, Computer simulations, Gas lasers, High power lasers, Carbon monoxide, Analytical research, Laser development, Optical simulations, Laser systems engineering, Mirrors

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Proceedings Article | 26 April 2016 Presentation

Effective transvascular drug delivery to glioma in rats by using a pulsed laser-induced photomechanical wave (Conference Presentation)

Yusuke Akutsu, Shunichi Sato, Arata Tomiyama, Yasuyuki Tsunoi, Satoko Kawauchi, Kentaro Mori, Mitsuhiro Terakawa

Proceedings Volume 9690, 96900H (2016) https://doi.org/10.1117/12.2212565

KEYWORDS: Pulsed laser operation, Luminescence, Tumors, Defense and security, Cancer, Veins, Cranial windows, Microscopy, Neurophotonics, Optogenetics

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Proceedings Article | 9 March 2016 Presentation + Paper

In vivo imaging of cerebral hemodynamics and regional oxygen saturation in rats with a digital red-green-blue camera

Izumi Nishidate, Yoshika Harasaki, Satoko Kawauchi, Shunichi Sato, Manabu Sato, Yasuaki Kokubo

Proceedings Volume 9690, 96900Q (2016) https://doi.org/10.1117/12.2212134

KEYWORDS: Oxygen, Hemodynamics, Digital cameras, Cameras, Brain, In vivo imaging, Monte Carlo methods, RGB color model, Tissues, Diffuse reflectance spectroscopy, Neuroimaging, Cerebral cortex

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SPIE Journal Paper | 27 July 2015 Open Access

Evaluation of light scattering and absorption properties of in vivo rat liver using a single-reflectance fiber probe during preischemia, ischemia–reperfusion, and postmortem

Sharmin Akter, Satoshi Maejima, Satoko Kawauchi, Shunichi Sato, Akinari Hinoki, Suefumi Aosasa, Junji Yamamoto, Izumi Nishidate

JBO, Vol. 20, Issue 07, 076010, (July 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.7.076010

KEYWORDS: Liver, Ischemia, Absorption, Tissues, In vivo imaging, Scattering, Light scattering, Oxygen, Nitrogen, Blood

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Proceedings Article | 14 July 2015 Paper

Visualization of hemodynamics and light scattering in exposed brain of rat using multispectral image reconstruction based on Wiener estimation method

Izumi Nishidate, Tomohiro Ishizuka, Keiichiro Yoshida, Satoko Kawauchi, Shunichi Sato, Manabu Sato

Proceedings Volume 9536, 95360Z (2015) https://doi.org/10.1117/12.2183759

KEYWORDS: Scattering, Absorption, Brain, Tissues, Reflectivity, Neuroimaging, In vivo imaging, Monte Carlo methods, Light scattering, RGB color model

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Proceedings Article | 10 March 2015 Paper

Photoacoustic imaging for transvascular drug delivery to the rat brain

Ryota Watanabe, Shunichi Sato, Yasuyuki Tsunoi, Satoko Kawauchi, Toshiya Takemura, Mitsuhiro Terakawa

Proceedings Volume 9305, 930523 (2015) https://doi.org/10.1117/12.2078505

KEYWORDS: Brain, Blood vessels, Neuroimaging, Head, Photoacoustic imaging, Visualization, Tissue optics, Acoustics, In vivo imaging, Carbon

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Proceedings Article | 10 March 2015 Paper

Multichannel fiber-based diffuse reflectance spectroscopy for the rat brain exposed to a laser-induced shock wave: comparison between ipsi- and contralateral hemispheres

Mai Miyaki, Satoko Kawauchi, Wataru Okuda, Hiroshi Nawashiro, Toshiya Takemura, Shunichi Sato, Izumi Nishidate

Proceedings Volume 9305, 930526 (2015) https://doi.org/10.1117/12.2078553

KEYWORDS: Optical fibers, Diffuse reflectance spectroscopy, Brain, Reflectivity, Bone, Signal detection, Blood, Pulsed laser operation, Oxygen, Optical switching

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Proceedings Article | 10 March 2015 Paper

In vivo estimation of light scattering and absorption properties of rat brain using single reflectance fiber probe during anoxic depolarization

Izumi Nishidate, Keiichiro Yoshida, Satoko Kawauchi, Shunichi Sato, Manabu Sato

Proceedings Volume 9305, 93050M (2015) https://doi.org/10.1117/12.2078986

KEYWORDS: Absorption, Tissue optics, Scattering, Light scattering, Brain, In vivo imaging, Tissues, Monte Carlo methods, Reflectivity, Diffuse reflectance spectroscopy

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SPIE Journal Paper | 11 February 2015 Open Access

In vivo estimation of light scattering and absorption properties of rat brain using a single-reflectance fiber probe during cortical spreading depression

Izumi Nishidate, Chiharu Mizushima, Keiichiro Yoshida, Satoko Kawauchi, Shunichi Sato, Manabu Sato

JBO, Vol. 20, Issue 02, 027003, (February 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.2.027003

KEYWORDS: Scattering, Absorption, Light scattering, Brain, Reflectivity, In vivo imaging, Tissues, Monte Carlo methods, Electrodes, Tissue optics

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Proceedings Article | 3 February 2015 Paper

Simulation code of high power discharge for iPhones

Takuro Hatsugai, Takuya Sugimoto, Manabu Taniwaki, Shunichi Sato, Mitsuhiro Iyoda

Proceedings Volume 9255, 92551H (2015) https://doi.org/10.1117/12.2065120

KEYWORDS: Information operations, Operating systems, Global Positioning System, Retina, High power lasers, Lithium, Cameras, Computer programming, Human-machine interfaces, Software development

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SPIE Journal Paper | 23 January 2015 Open Access

Multispectral imaging of absorption and scattering properties of in vivo exposed rat brain using a digital red-green-blue camera

Keiichiro Yoshida, Izumi Nishidate, Tomohiro Ishizuka, Satoko Kawauchi, Shunichi Sato, Manabu Sato

JBO, Vol. 20, Issue 05, 051026, (January 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.5.051026

KEYWORDS: Scattering, Absorption, Brain, Reflectivity, Tissues, In vivo imaging, Neuroimaging, Multispectral imaging, Hyperoxia, Light scattering

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SPIE Journal Paper | 2 December 2014 Open Access

Characteristics of laser-induced shock wave injury to the inner ear of rats

Takaomi Kurioka, Takeshi Matsunobu, Katsuki Niwa, Atsushi Tamura, Satoko Kawauchi, Yasushi Satoh, Shunichi Sato, Akihiro Shiotani

JBO, Vol. 19, Issue 12, 125001, (December 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.12.125001

KEYWORDS: Injuries, Ear, Tissues, Animal model studies, Bone, Neurons, Microscopes, Luminescence, Defense and security, Ruby lasers

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SPIE Journal Paper | 15 August 2014 Open Access

Real-time photoacoustic imaging system for burn diagnosis

Taiichiro Ida, Yasushi Kawaguchi, Satoko Kawauchi, Keiichi Iwaya, Hitoshi Tsuda, Daizoh Saitoh, Shunichi Sato, Toshiaki Iwai

JBO, Vol. 19, Issue 08, 086013, (August 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.8.086013

KEYWORDS: Imaging systems, Tissues, Skin, Blood vessels, Photoacoustic imaging, Sensors, Absorption, Injuries, Signal detection, Fiber lasers

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Proceedings Article | 5 March 2014 Paper

Near-infrared diffuse reflectance imaging of infarct core and peri-infarct depolarization in a rat middle cerebral artery occlusion model

Satoko Kawauchi, Izumi Nishidate, Hiroshi Nawashiro, Shunichi Sato

Proceedings Volume 8928, 89280K (2014) https://doi.org/10.1117/12.2038771

KEYWORDS: Diffuse reflectance spectroscopy, Reflectivity, Brain, Blood circulation, Light scattering, Near infrared, Arteries, Neuroimaging, Scattering, Tissues

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Proceedings Article | 5 March 2014 Paper

In vivo imaging of scattering and absorption properties of exposed brain using a digital red-green-blue camera

Izumi Nishidate, Keiichiro Yoshida, Satoko Kawauchi, Shunichi Sato, Manabu Sato

Proceedings Volume 8928, 89280N (2014) https://doi.org/10.1117/12.2041169

KEYWORDS: Scattering, Absorption, Tissues, Brain, Reflectivity, In vivo imaging, Neuroimaging, Image analysis, Spectroscopy, Cameras

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Proceedings Article | 5 March 2014 Paper

Optical monitoring of shock wave-induced spreading depolarization and concomitant hypoxemia in rat brain

Wataru Okuda, Satoko Kawauchi, Hiroshi Ashida, Shunichi Sato, Izumi Nishidate

Proceedings Volume 8928, 892829 (2014) https://doi.org/10.1117/12.2040899

KEYWORDS: Brain, Multispectral imaging, Neuroimaging, Oxygen, Diffuse reflectance spectroscopy, Tissues, Cell death, Blood vessels, Monte Carlo methods, Reflectivity

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Proceedings Article | 26 February 2014 Paper

Focusing of photomechanical waves with an optical lens for depth-targeted molecular delivery

Takuichirou Shimada, Shunichi Sato, Satoko Kawauchi, Hiroshi Ashida, Mitsuhiro Terakawa

Proceedings Volume 8941, 89410B (2014) https://doi.org/10.1117/12.2039227

KEYWORDS: Skin, Tissues, Wave propagation, Tissue optics, Molecular lasers, Plasma, Luminescence, Biomedical optics, Pulsed laser operation, Silicon

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Proceedings Article | 20 February 2014 Paper

Optical fiber-based photomechanical molecular delivery system

Koki Nakano, Shunichi Sato, Satoko Kawauchi, Hiroshi Ashida, Izumi Nishidate

Proceedings Volume 8938, 89381J (2014) https://doi.org/10.1117/12.2040904

KEYWORDS: Fiber lasers, Pulsed laser operation, Plasma, Optical fibers, Skin, Tissues, Silicon, Positron emission tomography, Quartz, Luminescence

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SPIE Journal Paper | 12 September 2013 Open Access

Low-level laser therapy for spinal cord injury in rats: effects of polarization

Takahiro Ando, Shunichi Sato, Hiroaki Kobayashi, Hiroshi Nawashiro, Hiroshi Ashida, Michael Hamblin

JBO, Vol. 18, Issue 09, 098002, (September 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.9.098002

KEYWORDS: Polarization, Spinal cord, Injuries, Laser therapeutics, Tissue optics, Acquisition tracking and pointing, Laser irradiation, Tissues, Photons, Optical fibers

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Proceedings Article | 24 June 2013 Paper

Multispectral imaging of hemodynamics in exposed brain of rat during cortical spreading depression using Wiener estimation method

Izumi Nishidate, Keiichiro Yoshida, Chiharu Mizushima, Satoko Kawauchi, Shunichi Sato, Manabu Sato

Proceedings Volume 8804, 88040A (2013) https://doi.org/10.1117/12.2032558

KEYWORDS: Reflectivity, Hemodynamics, Brain, Spectrometers, RGB color model, Tissue optics, Neuroimaging, In vivo imaging, Cerebral cortex, Tissues

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Proceedings Article | 25 March 2013 Paper

In vivo estimation of light scattering and absorption properties of rat brain using single reflectance fiber probe during cortical spreading depression

Izumi Nishidate, Chiharu Mizushima, Keiichiro Yoshida, Satoko Kawauchi, Shunichi Sato, Manabu Sato

Proceedings Volume 8578, 85782Y (2013) https://doi.org/10.1117/12.2003049

KEYWORDS: Absorption, Scattering, Tissue optics, Light scattering, In vivo imaging, Brain, Monte Carlo methods, Reflectivity, Tissues, Diffuse reflectance spectroscopy

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Proceedings Article | 4 March 2013 Paper

Real-time photoacoustic imaging system for clinical burn diagnosis

Taiichiro Ida, Yasushi Kawaguchi, Satoko Kawauchi, Keiichi Iwaya, Daizoh Saitoh, Shunichi Sato, Toshiaki Iwai

Proceedings Volume 8581, 858109 (2013) https://doi.org/10.1117/12.2002223

KEYWORDS: Skin, Tissues, Imaging systems, Blood, Photoacoustic imaging, Transducers, Injuries, Defense and security, Photoacoustic spectroscopy, Tissue optics

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Proceedings Article | 4 March 2013 Paper

Real-time photoacoustic imaging of rat deep brain: hemodynamic responses to hypoxia

Satoko Kawauchi, Hideaki Iwazaki, Taiichiro Ida, Tomoya Hosaka, Yasushi Kawaguchi, Hiroshi Nawashiro, Shunichi Sato

Proceedings Volume 8581, 85811R (2013) https://doi.org/10.1117/12.2002834

KEYWORDS: Hypoxia, Brain, Hemodynamics, Neuroimaging, Blood, Photoacoustic imaging, Real time imaging, Skull, Tissues, Transducers

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Proceedings Article | 4 March 2013 Paper

Acoustic-resolution photoacoustic imaging system with simple fiber illumination

Yasuyuki Tsunoi, Shunichi Sato, Ryota Watanabe, Satoko Kawauchi, Hiroshi Ashida, Mitsuhiro Terakawa

Proceedings Volume 8581, 85812U (2013) https://doi.org/10.1117/12.2003150

KEYWORDS: Acoustics, Imaging systems, Sensors, Skin, Tissue optics, Head, Ultrasonography, Natural surfaces, In vivo imaging, Photography

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Proceedings Article | 30 January 2013 Paper

Mutual utilization of simulation for high power application in the cloud computing environment

Manabu Taniwaki, Shunichi Sato, Takuya Okamura, Yoshitaka Maekawa, Mitsuhiro Iyoda

Proceedings Volume 8677, 86771K (2013) https://doi.org/10.1117/12.2008856

KEYWORDS: Clouds, Computer simulations, Internet, Gas lasers, Operating systems, Lithium, High power lasers, Numerical simulations, Distributed computing, Computing systems

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SPIE Journal Paper | 7 January 2013 Open Access

Diffuse light reflectance signals as potential indicators of loss of viability in brain tissue due to hypoxia: charge-coupled-device-based imaging and fiber-based measurement

Satoko Kawauchi, Izumi Nishidate, Yoichi Uozumi, Hiroshi Nawashiro, Hiroshi Ashida, Shunichi Sato

JBO, Vol. 18, Issue 01, 015003, (January 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.1.015003

KEYWORDS: Brain, Reflectivity, Scattering, Absorption, Tissues, Hypoxia, Light scattering, Neuroimaging, Optical fibers, Tissue optics

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Proceedings Article | 10 March 2012 Paper

Effects of polarization in low-level laser therapy of spinal cord injury in rats

Takahiro Ando, Shunichi Sato, Hiroaki Kobayashi, Hiroshi Nawashiro, Hiroshi Ashida, Michael Hamblin, Minoru Obara

Proceedings Volume 8211, 82110B (2012) https://doi.org/10.1117/12.906951

KEYWORDS: Polarization, Spinal cord, Injuries, Acquisition tracking and pointing, Tissue optics, Laser irradiation, Laser therapeutics, Laser tissue interaction, Tissues, Photons

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Proceedings Article | 10 March 2012 Paper

Control of anoxic depolarization in rat brain by near-infrared laser irradiation and its monitoring by intrinsic optical signal imaging

Satoko Kawauchi, Shunichi Sato, Yoichi Uozumi, Hiroshi Nawashiro, Miya Ishihara, Hiroshi Ashida

Proceedings Volume 8211, 82110C (2012) https://doi.org/10.1117/12.907802

KEYWORDS: Brain, Scattering, Hypoxia, Laser irradiation, Laser scattering, Neuroimaging, Light scattering, Near infrared, Acquisition tracking and pointing, Phototherapy

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Proceedings Article | 9 March 2012 Paper

Photoacoustic imaging of intravenously injected photosensitizer in rat burn models for efficient antibacterial photodynamic therapy

Yasuyuki Tsunoi, Shunichi Sato, Hiroshi Ashida, Mitsuhiro Terakawa

Proceedings Volume 8210, 82100D (2012) https://doi.org/10.1117/12.907644

KEYWORDS: Tissues, Sodium, Skin, Photoacoustic imaging, Photodynamic therapy, Photoacoustic spectroscopy, Injuries, Visualization, Blood vessels, Diffusion

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Proceedings Article | 9 March 2012 Paper

Control of burn wound sepsis in rats by methylene blue-mediated photodynamic treatment

Hiroyuki Hasegawa, Shunichi Sato, Satoko Kawauchi, Daizoh Saitoh, Nariyoshi Shinomiya, Hiroshi Ashida, Mitsuhiro Terakawa

Proceedings Volume 8210, 82100V (2012) https://doi.org/10.1117/12.907643

KEYWORDS: Bacteria, Light emitting diodes, Liver, Blood, Photodynamic therapy, Injuries, Absorption, Defense and security, Skin, Molecules

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SPIE Journal Paper | 1 October 2011 Open Access

Site-specific gene transfer into the rat spinal cord by photomechanical waves

Takahiro Ando, Minoru Obara, Shunichi Sato, Hiroshi Ashida, Terushige Toyooka, Yoichi Uozumi, Hiroshi Nawashiro

JBO, Vol. 16, Issue 10, 108002, (October 2011) https://doi.org/10.1117/12.10.1117/1.3642014

KEYWORDS: Spinal cord, Tissues, Injuries, Laser irradiation, Pulsed laser operation, Luminescence, Glia, Defense and security, Natural surfaces, Laser tissue interaction

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SPIE Journal Paper | 1 September 2011 Open Access

Targeted gene transfer into rat facial muscles by nanosecond pulsed laser-induced stress waves

Akihiro Kurita, Takeshi Matsunobu, Akinori Shiotani, Yasushi Satoh, Takahiro Ando, Shunichi Sato, Minoru Obara

JBO, Vol. 16, Issue 09, 098002, (September 2011) https://doi.org/10.1117/12.10.1117/1.3628313

KEYWORDS: Tissues, Pulsed laser operation, Skin, Nerve, Laser tissue interaction, Laser therapeutics, Nerve regeneration, Nd:YAG lasers, Defense and security, Ultrasonography

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Proceedings Article | 17 June 2011 Paper

In vivo determination of absorption and scattering properties in rat cerebral cortex using single reflectance fiber probe with two sourcecollector geometries

Izumi Nishidate, Satoko Kawauchi, Shunichi Sato, Miya Ishihara, Makoto Kikuchi, Manabu Sato

Proceedings Volume 8087, 80872P (2011) https://doi.org/10.1117/12.889659

KEYWORDS: Absorption, Scattering, In vivo imaging, Brain, Monte Carlo methods, Cerebral cortex, Tissue optics, Light scattering, Reflectivity, Diffuse reflectance spectroscopy

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Proceedings Article | 19 February 2011 Paper

Traumatic brain injury caused by laser-induced shock wave in rats: a novel laboratory model for studying blast-induced traumatic brain injury

Ben Hatano, Yoshihisa Matsumoto, Naoki Otani, Daizoh Saitoh, Shinichi Tokuno, Yasushi Satoh, Hiroshi Nawashiro, Yoshitaro Matsushita, Shunichi Sato

Proceedings Volume 7897, 78971V (2011) https://doi.org/10.1117/12.875909

KEYWORDS: Traumatic brain injury, Brain, Injuries, Defense and security, Luminescence, Pulsed laser operation, Animal model studies, Tissues, Laser tissue interaction, Blood brain barrier

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Proceedings Article | 18 February 2011 Paper

Efficient delivery of small interfering RNA into injured spinal cords in rats by photomechanical waves

Takahiro Ando, Shunichi Sato, Terushige Toyooka, Hiroaki Kobayashi, Hiroshi Nawashiro, Hiroshi Ashida, Minoru Obara

Proceedings Volume 7883, 78834S (2011) https://doi.org/10.1117/12.873513

KEYWORDS: Spinal cord, Tissues, Proteins, Injuries, Luminescence, Defense and security, In vivo imaging, Medical research, Pulsed laser operation, Nervous system

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Proceedings Article | 12 February 2011 Paper

Near-infrared scattering imaging of depolarization waves in a rat hypoxic brain model and its application to assessment of brain tissue reversibility

Satoko Kawauchi, Shunichi Sato, Yoichi Uozumi, Hiroshi Nawashiro, Miya Ishihara, Makoto Kikuchi

Proceedings Volume 7907, 79070M (2011) https://doi.org/10.1117/12.874615

KEYWORDS: Brain, Scattering, Light scattering, Neuroimaging, Tissues, Hypoxia, Tissue optics, Near infrared, Diffuse reflectance spectroscopy, Reflectivity

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Proceedings Article | 11 February 2011 Paper

Depth-targeted transvascular drug delivery by using annular-shaped photomechanical waves

Takuya Akiyama, Shunichi Sato, Hiroshi Ashida, Mitsuhiro Terakawa

Proceedings Volume 7902, 79020X (2011) https://doi.org/10.1117/12.874383

KEYWORDS: Tissues, Blood vessels, Luminescence, Molecules, Superposition, Veins, Natural surfaces, Skin, Axicons, Laser tissue interaction

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SPIE Journal Paper | 1 February 2011 Open Access

Light-scattering signal may indicate critical time zone to rescue brain tissue after hypoxia

Satoko Kawauchi, Miya Ishihara, Makoto Kikuchi, Shunichi Sato, Yoichi Uozumi, Hiroshi Nawashiro

JBO, Vol. 16, Issue 02, 027002, (February 2011) https://doi.org/10.1117/12.10.1117/1.3542046

KEYWORDS: Brain, Reflectivity, Oxygen, Hypoxia, Tissue optics, Scattering, Near infrared, Light scattering, Diffuse reflectance spectroscopy, Electroencephalography

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Proceedings Article | 16 November 2010 Paper

Numerical analysis of high power gas laser accelerated by Xgrid computing technology

Manabu Taniwaki, Shunichi Sato, Hiroyuki Katagiri, Yoshitaka Maekawa, Mitsuhiro Iyoda

Proceedings Volume 7751, 77511E (2010) https://doi.org/10.1117/12.871598

KEYWORDS: Gas lasers, High power lasers, Numerical analysis, Optical simulations, Internet, Computer security, Defense technologies, Computing systems, Analytical research, Human-machine interfaces

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Proceedings Article | 5 March 2010 Paper

In vivo photodynamic inactivation of Psuedomonas aeruginosa in burned skin in rats

Akihiro Hirao, Shunichi Sato, Mitsuhiro Terakawa, Daizoh Saitoh, Nariyoshi Shinomiya, Hiroshi Ashida, Minoru Obara

Proceedings Volume 7551, 75510V (2010) https://doi.org/10.1117/12.841495

KEYWORDS: Photodynamic therapy, Bacteria, Skin, Picosecond phenomena, Tissues, In vivo imaging, Tissue optics, Defense and security, Natural surfaces, Medical research

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Proceedings Article | 26 February 2010 Paper

Correlation between light scattering signal and tissue reversibility in rat brain exposed to hypoxia

Satoko Kawauchi, Shunichi Sato, Yoichi Uozumi, Hiroshi Nawashiro, Miya Ishihara, Makoto Kikuchi

Proceedings Volume 7573, 75730U (2010) https://doi.org/10.1117/12.841489

KEYWORDS: Brain, Light scattering, Diffuse reflectance spectroscopy, Tissue optics, Oxygen, Scattering, Hypoxia, Tissues, Signal detection, Nitrogen

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Proceedings Article | 24 February 2010 Paper

Photoacoustic diagnosis of edema in rat burned skin

Ken Yoshida, Shunichi Sato, Kosuke Hatanaka, Daizoh Saitoh, Hiroshi Ashida, Toshihisa Sakamoto, Minoru Obara

Proceedings Volume 7564, 75641C (2010) https://doi.org/10.1117/12.841438

KEYWORDS: Tissues, Skin, Photoacoustic spectroscopy, Injuries, Absorption, Blood vessels, Signal detection, Defense and security, Tissue optics, Natural surfaces

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Proceedings Article | 23 February 2010 Paper

Effects of laser parameters on propagation characteristics of laser-induced stress wave for gene transfer

Takahiro Ando, Shunichi Sato, Mitsuhiro Terakawa, Hiroshi Ashida, Minoru Obara

Proceedings Volume 7562, 75620Y (2010) https://doi.org/10.1117/12.840815

KEYWORDS: Skin, Tissues, Wave propagation, Laser tissue interaction, Laser therapeutics, Pulsed laser operation, Laser energy, In vivo imaging, Nervous system, Plasma

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SPIE Journal Paper | 1 November 2009 Open Access

Accelerated adhesion of grafted skin by laser-induced stress wave-based gene transfer of hepatocyte growth factor

Kazuya Aizawa, Shunichi Sato, Mitsuhiro Terakawa, Daizoh Saitoh, Hitoshi Tsuda, Hiroshi Ashida, Minoru Obara

JBO, Vol. 14, Issue 06, 064043, (November 2009) https://doi.org/10.1117/12.10.1117/1.3253325

KEYWORDS: Skin, Tissues, Transplantation, Wound healing, Blood circulation, Doppler effect, Proteins, Defense and security, Laser tissue interaction, Imaging systems

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Proceedings Article | 24 February 2009 Paper

In vivo transcranial measurement of light scattering in rat brains during hypoxia

Satoko Kawauchi, Shunichi Sato, Yoichi Uozumi, Hiroshi Nawashiro, Miya Ishihara, Makoto Kikuchi

Proceedings Volume 7187, 71870U (2009) https://doi.org/10.1117/12.807967

KEYWORDS: Light scattering, Reflectivity, Brain, Diffuse reflectance spectroscopy, Tissue optics, Scattering, Hypoxia, In vivo imaging, Blood, Optical testing

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Proceedings Article | 23 February 2009 Paper

Photoacoustic monitoring of granulation tissue grown in grafted artificial dermis

Kousuke Hatanaka, Shunichi Sato, Daizoh Saitoh, Hiroshi Ashida, Toshihisa Sakamoto

Proceedings Volume 7161, 71610Z (2009) https://doi.org/10.1117/12.808143

KEYWORDS: Tissues, Advanced distributed simulations, Tissue optics, Photoacoustic spectroscopy, Skin, Signal detection, Blood vessels, Defense and security, Silicon, Collagen

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Proceedings Article | 19 February 2009 Paper

Accelerated adhesion of grafted skins by laser-induced stress wave-based gene transfer of hepatocyte growth factor

Kazuya Aizawa, Shunichi Sato, Daizoh Saitoh, Hitoshi Tsuda, Hiroshi Ashida, Minoru Obara

Proceedings Volume 7161, 71610L (2009) https://doi.org/10.1117/12.808663

KEYWORDS: Skin, Transplantation, Tissues, Blood circulation, Doppler effect, Wound healing, Defense and security, Plasma, Blood, Pulsed laser operation

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Proceedings Article | 12 February 2009 Paper

In vivo photoacoustic monitoring of photosensitizer in skin: application to dosimetry for antibacterial photodynamic treatment

Akihiro Hirao, Shunichi Sato, Daizoh Saitoh, Nariyoshi Shinomiya, Hiroshi Ashida, Minoru Obara

Proceedings Volume 7177, 71772C (2009) https://doi.org/10.1117/12.808480

KEYWORDS: Sodium, Skin, Tissue optics, Photoacoustic spectroscopy, Blood, In vivo imaging, Tissues, Signal attenuation, Signal detection, Acoustics

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SPIE Journal Paper | 1 November 2008 Open Access

Photoacoustic monitoring of burn healing process in rats

Kazuya Aizawa, Shunichi Sato, Daizoh Saitoh, Hiroshi Ashida, Minoru Obara

JBO, Vol. 13, Issue 06, 064020, (November 2008) https://doi.org/10.1117/12.10.1117/1.3028005

KEYWORDS: Tissues, Blood, Photoacoustic spectroscopy, Skin, Wound healing, Hemodynamics, Injuries, Signal processing, Blood vessels, Oxygen

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Proceedings Article | 28 February 2008 Paper

Monitoring of healing process of burns based on multiwavelength photoacoustic measurement

Kazuya Aizawa, Shunichi Sato, Daizoh Saitoh, Hiroshi Ashida, Minoru Obara

Proceedings Volume 6856, 685605 (2008) https://doi.org/10.1117/12.764247

KEYWORDS: Photoacoustic spectroscopy, Injuries, Tissues, Absorption, Wound healing, Blood, Skin, Oxygen, Hemodynamics, Defense and security

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Proceedings Article | 22 February 2008 Paper

Relationship between light scattering and absorption due to cytochrome c oxidase reduction during loss of tissue viability in brains of rats

Satoko Kawauchi, Shunichi Sato, Hidetoshi Ooigawa, Hiroshi Nawashiro, Miya Ishihara, Makoto Kikuchi

Proceedings Volume 6864, 68640K (2008) https://doi.org/10.1117/12.762811

KEYWORDS: Light scattering, Brain, Absorption, Scattering, Tissue optics, Tissues, Diffuse reflectance spectroscopy, Blood, Defense and security, Intrinsic optical signal

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Proceedings Article | 1 August 2007 Paper

Thin film synthesis of wurtzite boron nitride by femtosecond pulsed laser deposition

Tasuku Shimizu, Takahiro Nakamura, Shunichi Sato

Proceedings Volume 6785, 67850E (2007) https://doi.org/10.1117/12.755970

KEYWORDS: Thin films, Boron, Femtosecond phenomena, Pulsed laser deposition, Crystals, Silicon, Thin film deposition, Silicon films, Transmission electron microscopy, FT-IR spectroscopy

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Proceedings Article | 1 August 2007 Paper

Generation of a radially polarized Nd:YVO₄ laser beam

Kazuhiro Yonezawa, Yuichi Kozawa, Takahiro Nakamura, Shunichi Sato

Proceedings Volume 6785, 678507 (2007) https://doi.org/10.1117/12.755495

KEYWORDS: Crystals, Laser crystals, Polarization, Transmission electron microscopy, Birefringence, Semiconductor lasers, Laser resonators, Mirrors, Superposition, Optical pumping

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Proceedings Article | 11 July 2007 Paper

Intrinsic optical signals of brains in rats during loss of tissue viability: effect of brain temperature

Satoko Kawauchi, Shunichi Sato, Hidetoshi Ooigawa, Hiroshi Nawashiro, Makoto Kikuchi

Proceedings Volume 6628, 66280A (2007) https://doi.org/10.1117/12.729530

KEYWORDS: Brain, Tissue optics, Scattering, Light scattering, Intrinsic optical signal, Diffuse reflectance spectroscopy, Tissues, Signal attenuation, Dendrites, Mode conditioning cables

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SPIE Journal Paper | 1 May 2007 Open Access

Enhanced angiogenesis in grafted skins by laser-induced stress wave-assisted gene transfer of hepatocyte growth factor

Mitsuhiro Terakawa, Shunichi Sato, Daizoh Saitoh, Hitoshi Tsuda, Hiroshi Ashida, Hirofumi Okano, Minoru Obara

JBO, Vol. 12, Issue 03, 034031, (May 2007) https://doi.org/10.1117/12.10.1117/1.2745313

KEYWORDS: Skin, Tissues, Transplantation, In vivo imaging, Blood vessels, Defense and security, Laser therapeutics, Medicine, Medical research, Proteins

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Proceedings Article | 26 April 2007 Paper

Computer analysis of external effect on the discharge characteristics of gas mixture

Manabu Taniwaki, Kouki Shimizu, Shunichi Sato, Yoshihiro Tsuchiya, Yoshitaka Maekawa, Mitsuhiro Iyoda

Proceedings Volume 6346, 63462K (2007) https://doi.org/10.1117/12.739107

KEYWORDS: Magnetism, Computer programming, Java, Analytical research, Medical research, Differential equations, Personal digital assistants, Laser applications, Defense and security, Defense technologies

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Proceedings Article | 26 April 2007 Paper

Flexible laser simulator constructed in the integrated information processing environment

Yoshihiro Tsuchiya, Manabu Taniwaki, Kouki Shimizu, Shunichi Sato, Yoshitaka Maekawa, Mitsuhiro Iyoda

Proceedings Volume 6346, 63462T (2007) https://doi.org/10.1117/12.739119

KEYWORDS: Optical simulations, Switches, Laser processing, Computer hardware, Data processing, Binary data, Operating systems, Human-machine interfaces, Laser applications, Computer simulations

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Proceedings Article | 26 February 2007 Paper

Changes in intrinsic optical signals during loss of tissue viability of brains in rats: effect of brain temperature

Satoko Kawauchi, Shunichi Sato, Hidetoshi Ooigawa, Hiroshi Nawashiro, Makoto Kikuchi

Proceedings Volume 6434, 64341O (2007) https://doi.org/10.1117/12.700209

KEYWORDS: Brain, Tissue optics, Scattering, Light scattering, Diffuse reflectance spectroscopy, Intrinsic optical signal, Signal attenuation, Temperature metrology, Absorption, Tissues

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Proceedings Article | 19 February 2007 Paper

Enhanced angiogenesis in grafted skins by gene transfer of human hepatocyte growth factor using laser-induced stress waves

Mitsuhiro Terakawa, Shunichi Sato, Daizoh Saitoh, Hitoshi Tsuda, Hiroshi Ashida, Hideyuki Okano, Minoru Obara

Proceedings Volume 6435, 643513 (2007) https://doi.org/10.1117/12.700215

KEYWORDS: Skin, Laser therapeutics, Transplantation, Defense and security, Blood vessels, Medical research, Medicine, Oxygen, Tissues, Laser tissue interaction

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Proceedings Article | 6 February 2007 Paper

Laser-induced stress wave-assisted gene transfection: improved transfection efficiency with cationic liposome-modified plasmid DNA

Risa Otsuka, Mitsuhiro Terakawa, Shunichi Sato, Yasushi Satoh, Kunio Takishima, Hiroshi Ashida, Minoru Obara

Proceedings Volume 6435, 643518 (2007) https://doi.org/10.1117/12.701734

KEYWORDS: Luminescence, In vitro testing, Green fluorescent protein, Microscopes, Tissue optics, Polymers, Defense and security, Solids, Pulsed laser operation, Q switched lasers

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Proceedings Article | 7 June 2006 Paper

Gene transfer of human hepatocyte growth factor by the use of nanosecond pulsed laser-induced stress waves

Mitsuhiro Terakawa, Shunichi Sato, Daizoh Saitoh, Makoto Hasegawa, Hiroshi Ashida, Hideyuki Okano, Minoru Obara

Proceedings Volume 6261, 626133 (2006) https://doi.org/10.1117/12.668965

KEYWORDS: Skin, Proteins, Pulsed laser operation, In vivo imaging, Q switched lasers, Laser therapeutics, Defense and security, Medical research, Nd:YAG lasers, High power lasers

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Proceedings Article | 6 March 2006 Paper

Efficacy of photodynamic inactivation against Pseudomonas aeruginosa with pulsed light and CW light excitation

Tohru Yamaguchi, Shunichi Sato, Satoko Kawauchi, Mitsuhiro Terakawa, Nariyoshi Shinomiya, Daizoh Saitoh, Hiroshi Ashida, Minoru Obara

Proceedings Volume 6139, 61390V (2006) https://doi.org/10.1117/12.653078

KEYWORDS: Absorption, Tissue optics, Skin, Signal attenuation, Photodynamic therapy, Molecules, Transmittance, Bacteria, Oxygen

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Proceedings Article | 1 March 2006 Paper

Development of a noninvasive multifunctional measurement method using nanosecond pulsed laser for evaluation of regenerative medicine for articular cartilage

Miya Ishihara, Masato Sato, Nagatoshi Kaneshiro, Genya Mitani, Shunichi Sato, Masayuki Ishihara, Joji Mochida, Makoto Kikuchi

Proceedings Volume 6084, 60840V (2006) https://doi.org/10.1117/12.645888

KEYWORDS: Cartilage, Collagen, Tissues, Regenerative medicine, Photoacoustic spectroscopy, Luminescence, Pulsed laser operation, Time resolved spectroscopy, Tissue optics, Spectroscopy

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Proceedings Article | 22 February 2006 Paper

Changes in diffuse reflectance intensity and autofluorescence for brain tissue in rats during loss of tissue viability

Satoko Kawauchi, Shunichi Sato, Hidetoshi Ooigawa, Hiroshi Nawashiro, Katsuji Shima, Makoto Kikuchi

Proceedings Volume 6078, 607831 (2006) https://doi.org/10.1117/12.645782

KEYWORDS: Light scattering, Brain, Tissue optics, Tissues, Reflectivity, Diffuse reflectance spectroscopy, Absorption, Copper, Optical fibers, Luminescence

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Proceedings Article | 22 February 2006 Paper

Targeted gene transfer of human hepatocyte growth factor into rat skin by the use of laser-induced stress waves

Mitsuhiro Terakawa, Shunichi Sato, Daizoh Saitoh, Hiroshi Ashida, Hideyuki Okano, Minoru Obara

Proceedings Volume 6078, 60780T (2006) https://doi.org/10.1117/12.645473

KEYWORDS: Skin, Proteins, Laser therapeutics, In vivo imaging, Defense and security, Medicine, Energy efficiency, Laser tissue interaction, Laser bonding, Electronics

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SPIE Journal Paper | 1 January 2006 Open Access

Intracellular kinetics of ATX-S10·Na(II) and its correlation with photochemical reaction dynamics during a pulsed photosensitization process: effect of pulse repetition rate

Satoko Kawauchi, Shunichi Sato, Yuji Morimoto, Makoto Kikuchi

JBO, Vol. 11, Issue 01, 014005, (January 2006) https://doi.org/10.1117/12.10.1117/1.2160387

KEYWORDS: Luminescence, Sodium, Oxygen, Photomicroscopy, Photodynamic therapy, Molecules, Microscopes, Statistical analysis, Defense and security, Switching

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SPIE Journal Paper | 1 January 2006 Open Access

In vitro gene transfer to mammalian cells by the use of laser-induced stress waves: effects of stress wave parameters, ambient temperature, and cell type

Mitsuhiro Terakawa, Shunichi Sato, Hiroshi Ashida, Kazuya Aizawa, Maki Uenoyama, Yoshinori Masaki, Minoru Obara

JBO, Vol. 11, Issue 01, 014026, (January 2006) https://doi.org/10.1117/12.10.1117/1.2160407

KEYWORDS: In vitro testing, Laser therapeutics, Plasma, Pulsed laser operation, Luminescence, Tissues, Laser energy, In vivo imaging, Temperature metrology, Glasses

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SPIE Journal Paper | 1 November 2005 Open Access

Transcranial measurement of diffuse light reflectance from cold-injured brains in rats

Yoshinori Ueda, Shunichi Sato, Hiroshi Ashida, Hidetoshi Ooigawa, Hiroshi Nawashiro, Katsuji Shima, Daizoh Saitoh, Yoshiaki Okada, Minoru Obara

JBO, Vol. 10, Issue 06, 064010, (November 2005) https://doi.org/10.1117/12.10.1117/1.2136386

KEYWORDS: Brain, Reflectivity, Injuries, Tissue optics, Tissues, Optical testing, Light scattering, Blood, Scattering, Blood circulation

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SPIE Journal Paper | 1 November 2005 Open Access

Targeted DNA transfection into the mouse central nervous system using laser-induced stress waves

Yasushi Sato, Kunio Takishima, Yasunari Kanda, Katsushige Mizuno, Yasuhiro Watanabe, Mitsuhiro Terakawa, Minoru Obara, Shogo Endo, Hidetoshi Ooigawa, Hiroshi Nawashiro, Shunichi Sato

JBO, Vol. 10, Issue 06, 060501, (November 2005) https://doi.org/10.1117/12.10.1117/1.2128432

KEYWORDS: Brain, Tissues, Nervous system, Defense and security, Luminescence, Pulsed laser operation, Natural surfaces, Biochemistry, Pharmacology, Neuroscience

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SPIE Journal Paper | 1 November 2005 Open Access

Measurement of burn depths in rats using multiwavelength photoacoustic depth profiling

Mutsuo Yamazaki, Shunichi Sato, Hiroshi Ashida, Daizo Saito, Yoshiaki Okada, Minoru Obara

JBO, Vol. 10, Issue 06, 064011, (November 2005) https://doi.org/10.1117/12.10.1117/1.2137287

KEYWORDS: Skin, Tissues, Blood, Absorption, Tissue optics, Photoacoustic spectroscopy, Sensors, Blood vessels, Profiling, Injuries

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Proceedings Article | 27 August 2005 Paper

Antimicrobial photodynamic treatment of gram-negative bacteria with a cationic phenothiazine dye under pulsed light irradiation

Satoko Kawauchi, Shunichi Sato, Toru Yamaguchi, Nariyoshi Shinomiya, Daizo Saito, Hiroshi Ashida, Minoru Obara, Makoto Kikuchi

Proceedings Volume 5863, 58630W (2005) https://doi.org/10.1117/12.633093

KEYWORDS: Bacteria, Picosecond phenomena, Defense and security, Oxygen, In vitro testing, Photoacoustic spectroscopy, Biomedical optics, Lung cancer, Photodynamic therapy

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Proceedings Article | 27 August 2005 Paper

Gene transfer by the use of laser-induced stress wave: cell type dependence of transfection efficiency

Mitsuhiro Terakawa, Shunichi Sato, Hiroshi Ashida, Minoru Obara

Proceedings Volume 5863, 58630E (2005) https://doi.org/10.1117/12.633104

KEYWORDS: Laser tissue interaction, Luminescence, Electronics, Electrical engineering, Biomedical optics, Ovary, Q switched lasers, Defense and security, Medical research, Safety

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Proceedings Article | 25 April 2005 Paper

Transcranial measurement of diffuse light reflectance from brain edema in rats: effect of change in the blood flow

Yoshinori Ueda, Shunichi Sato, Hidetoshi Ooigawa, Hiroshi Nawashiro, Daizoh Saitoh, Katsuji Shima, Yoshiaki Okada, Hiroshi Ashida, Minoru Obara

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.590008

KEYWORDS: Brain, Injuries, Reflectivity, Diffuse reflectance spectroscopy, Blood, Blood circulation, Scattering, Optical testing, Absorption, Light scattering

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Proceedings Article | 25 April 2005 Paper

Photoacoustic detection of neovascularities in skin graft

Mutsuo Yamazaki, Shunichi Sato, Daizo Saitoh, Miya Ishihara, Yoshiaki Okada, Hiroshi Ashida, Minoru Obara

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.588879

KEYWORDS: Skin, Photoacoustic spectroscopy, Signal detection, Transplantation, Tissues, Transducers, Defense and security, Blood circulation, Chromophores, Blood

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Proceedings Article | 15 April 2005 Paper

Usefulness of the photoacoustic measurement method for monitoring the regenerative process of full-thickness defects in articular cartilage using tissue-engineering technology

Miya Ishihara, Masato Sato, Shunichi Sato, Toshiyuki Kikuchi, Genya Mitani, Nagatoshi Kaneshiro, Masayuki Ishihara, Joji Mochida, Makoto Kikuchi

Proceedings Volume 5695, (2005) https://doi.org/10.1117/12.591890

KEYWORDS: Cartilage, Photoacoustic spectroscopy, Tissue optics, Transplantation, Tissues, In vivo imaging, Surgery, Transducers, Regenerative medicine, In vitro testing

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Proceedings Article | 15 April 2005 Paper

In vitro gene transfer by the use of laser-induced stress wave: effect of laser irradiation conditions on transfection efficiency

Mitsuhiro Terakawa, Shunichi Sato, Makoto Ogura, Yoshinori Masaki, Maki Uenoyama, Hitoshi Wakisaka, Hiroshi Ashida, Minoru Obara

Proceedings Volume 5695, (2005) https://doi.org/10.1117/12.588852

KEYWORDS: In vitro testing, Laser therapeutics, Laser irradiation, Plasma, Laser energy, Laser tissue interaction, In vivo imaging, Pulsed laser operation, Defense and security, Medical research

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Proceedings Article | 8 April 2005 Paper

Reaction dynamics during pulsed light activation of ATX-S10 Na(II)-sensitized cell cultures: analysis based on fluorescence-oxygen diagram

Satoko Kawauchi, Shunichi Sato, Yuji Morimoto, Makoto Kikuchi

Proceedings Volume 5689, (2005) https://doi.org/10.1117/12.589569

KEYWORDS: Luminescence, Oxygen, Photodynamic therapy, Microscopy, Switching, Statistical analysis, Microscopes, Defense and security, Tissue optics, Light sources

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Proceedings Article | 8 April 2005 Paper

Pulsed photodynamic inactivation of gram-negative bacteria: electron microscopic study

Masafumi Nagasawa, Shunichi Sato, Satoko Kawauchi, Nariyoshi Shinomiya, Daizo Saito, Hiroshi Ashida, Minoru Obara

Proceedings Volume 5689, (2005) https://doi.org/10.1117/12.589993

KEYWORDS: Bacteria, Photodynamic therapy, Transmission electron microscopy, Photomicroscopy, Scanning electron microscopy, Defense and security, Electron microscopy, Luminescence, In vitro testing, Resistance

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Proceedings Article | 23 March 2005 Paper

Simulation for discharge excited gas mixture executed by cellular phones

Toshihiko Tabei, Yoshitaka Maekawa, Mitsuhiro Iyoda, Manabu Taniwaki, Kouki Shimizu, Shunichi Sato

Proceedings Volume 5777, (2005) https://doi.org/10.1117/12.611197

KEYWORDS: Java, Computer programming, Data storage, Computer simulations, Internet, Computer programming languages, Operating systems, Optical simulations, Medical research, Data communications

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Proceedings Article | 23 March 2005 Paper

Improvement of simulation computing for discharge exited gas lasers

Manabu Taniwaki, Kouki Shimizu, Shunichi Sato, Toshihiko Tabei, Yoshitaka Maekawa, Mitsuhiro Iyoda

Proceedings Volume 5777, (2005) https://doi.org/10.1117/12.611195

KEYWORDS: Computing systems, Computer simulations, Gas lasers, Parallel computing, Optical simulations, Computer architecture, Device simulation, Operating systems, Solid state lighting, Medical research

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Proceedings Article | 21 October 2004 Paper

Wide spectral width of frequency-shifted-feedback semiconductor laser

Shunichi Sato, Masaki Kawasaki

Proceedings Volume 5581, (2004) https://doi.org/10.1117/12.582798

KEYWORDS: Semiconductor lasers, Reflectivity, Laser resonators, Bragg cells, Mirrors, Diffraction gratings, Homodyne detection, Antireflective coatings, Spectrum analysis, Modulation

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Proceedings Article | 21 October 2004 Paper

The effect of deposition parameters on the boron nitride films grown on Si(100) by PLD with nanosecond pulses

C. Luculescu, Shunichi Sato, Constantin Fenic

Proceedings Volume 5581, (2004) https://doi.org/10.1117/12.582922

KEYWORDS: Boron, Nitrogen, Protactinium, Nd:YAG lasers, FT-IR spectroscopy, Scanning electron microscopy, Oxides, Oxygen, Ions, Nickel

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Proceedings Article | 13 July 2004 Paper

Measurement of backscattered light from the cold-injured brain: feasibility study of noninvasive monitoring of brain edema

Yoshinori Ueda, Shunichi Sato, Daizoh Saitoh, Hiroshi Nawashiro, Hidetoshi Ooigawa, Katsuji Shima, Yoshiaki Okada, Hiroshi Ashida, Minoru Obara

Proceedings Volume 5312, (2004) https://doi.org/10.1117/12.533024

KEYWORDS: Brain, Injuries, Skull, Optical testing, Light scattering, Scattering, Tissue optics, Optical fibers, Helium neon lasers, Reflectivity

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Proceedings Article | 12 July 2004 Paper

Adhesion monitoring of skin grafts by photoacoustic measurement: experiment using rat allograft models

Mutsuo Yamazaki, Shunichi Sato, Daizo Saito, Yoshiaki Okada, Hiroshi Ashida, Minoru Obara

Proceedings Volume 5320, (2004) https://doi.org/10.1117/12.530200

KEYWORDS: Skin, Photoacoustic spectroscopy, Tissues, Transducers, Visualization, Defense and security, Nd:YAG lasers, Signal detection, Electronics, Electrical engineering

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Proceedings Article | 1 July 2004 Paper

In vitro gene transfer by the application of laser-induced stress wave: effect of cellular heating

Mitsuhiro Terakawa, Shunichi Sato, Makoto Ogura, Kuniaki Nakanishi, Yoshinori Masaki, Maki Uenoyama, Hitoshi Wakisaka, Hiroshi Ashida, Minoru Obara

Proceedings Volume 5322, (2004) https://doi.org/10.1117/12.530815

KEYWORDS: In vitro testing, Laser therapeutics, Plasma, Laser irradiation, Luminescence, Defense and security, Medical research, Green fluorescent protein, Pulsed laser operation, Sodium

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Proceedings Article | 1 July 2004 Paper

Applicability of photoacoustic measurement for biomechanical characterization: from in vitro engineered tissue characterization to in vivo diagnosis

Miya Ishihara, Masato Sato, Shunichi Sato, Toshiyuki Kikuchi, Masayuki Ishihara, Joji Mochida, Kyosuke Fujikawa, Makoto Kikuchi

Proceedings Volume 5319, (2004) https://doi.org/10.1117/12.530527

KEYWORDS: Photoacoustic spectroscopy, Cartilage, In vivo imaging, Reflectivity, Transducers, Tissue optics, Optical fibers, Laser tissue interaction, Optical parametric oscillators, Tissues

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Proceedings Article | 14 June 2004 Paper

Pulsed photodynamic inactivation of gram-negative bacteria: in vitro study using methylene blue

Masafumi Nagasawa, Shunichi Sato, Satoko Kawauchi, Nariyoshi Shinomiya, Daizo Saito, Hiroshi Ashida, Minoru Obara

Proceedings Volume 5315, (2004) https://doi.org/10.1117/12.530817

KEYWORDS: Bacteria, Photodynamic therapy, In vitro testing, Defense and security, Cell death, Molecules, Biomedical optics, Optical parametric oscillators, Electronics, Electrical engineering

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Proceedings Article | 10 June 2004 Paper

Sealed hollow waveguide for catheter-based pulsed photodynamic therapy

Shunichi Sato, Satoko Kawauchi, Yi-Wei Shi, Yuji Matsuura, Mitsunobu Miyagi

Proceedings Volume 5317, (2004) https://doi.org/10.1117/12.533376

KEYWORDS: Waveguides, Hollow waveguides, Photodynamic therapy, Quartz, Polymer multimode waveguides, Polymers, Silver, Medium wave, Optical parametric oscillators, Optical fibers

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SPIE Journal Paper | 1 January 2004 Open Access

Assessment of expressions of heat shock protein (HSP 72) and apoptosis after ArF excimer laser ablation of the cornea

Miya Ishihara, Masato Sato, Shunichi Sato, Tsunenori Arai, Minoru Obara, Makoto Kikuchi

JBO, Vol. 9, Issue 01, (January 2004) https://doi.org/10.1117/12.10.1117/1.1630605

KEYWORDS: Laser ablation, Cell death, Excimer lasers, Temperature metrology, Cornea, Proteins, Laser optics, Tissues, Defense and security, Monoclonal antibodies

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Proceedings Article | 10 November 2003 Paper

Implementation of simulation codes for gas flow CO lasers by the combination of server-side and client-side processing

Manabu Taniwaki, Kouki Shimizu, Shunichi Sato, Yohei Takatsu, Yoshitaka Maekawa, Mitsuhiro Iyoda

Proceedings Volume 5120, (2003) https://doi.org/10.1117/12.515487

KEYWORDS: Java, Gas lasers, Optical simulations, Computer simulations, Laser development, Human-machine interfaces, Internet, Medical research, Distributed computing, Operating systems

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Proceedings Article | 10 November 2003 Paper

PDA simulator for the power distribution analyses of discharge-excited gaseous media

Yohei Takatsu, Yoshitaka Maekawa, Mitsuhiro Iyoda, Manabu Taniwaki, Kouki Shimizu, Shunichi Sato

Proceedings Volume 5120, (2003) https://doi.org/10.1117/12.515486

KEYWORDS: Personal digital assistants, Computer simulations, Optical simulations, Analytical research, Medical research, Neon, Computer programming, Defense technologies, Computer science

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Proceedings Article | 12 September 2003 Paper

Photosensitizer delivery into tissue and cells by simultaneous application of laser-induced stress wave and heating

Makoto Ogura, Mitsuhiro Terakawa, Shunichi Sato, Hiroshi Ashida, Minoru Obara

Proceedings Volume 4949, (2003) https://doi.org/10.1117/12.476137

KEYWORDS: Skin, Fiber lasers, Laser tissue interaction, Photodynamic therapy, Laser therapeutics, Confocal microscopy, Sodium, Pulsed laser operation, Laser scanners, Microscopes

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Proceedings Article | 27 August 2003 Paper

Biomechanical characterization of tissue-engineered cartilages by photoacoustic measurement

Miya Ishihara, Masato Sato, Shunichi Sato, Toshiyuki Kikuchi, Kyosuke Fujikawa, Makoto Kikuchi

Proceedings Volume 4961, (2003) https://doi.org/10.1117/12.477659

KEYWORDS: Photoacoustic spectroscopy, Tissues, Cartilage, Tissue optics, Laser tissue interaction, Tissue engineering, Optical parametric oscillators, Acoustics, Defense and security, Transducers

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Proceedings Article | 1 July 2003 Paper

Photoacoustic diagnosis of burns in rats: two-dimensional photoacoustic imaging of burned tissue

Mutsuo Yamazaki, Shunichi Sato, Daizo Saito, Yoshiaki Okada, Akira Kurita, Makoto Kikuchi, Hiroshi Ashida, Minoru Obara

Proceedings Volume 4960, (2003) https://doi.org/10.1117/12.477638

KEYWORDS: Photoacoustic spectroscopy, Tissue optics, Skin, Photoacoustic imaging, Biomedical optics, Time metrology, Blood, Injuries, Sensors, Wound healing

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Proceedings Article | 13 June 2003 Paper

Repetition-rate-dependent oxygen consumption modifies cytotoxicity in photodynamic therapy using pulsed light

Satoko Kawauchi, Yuji Morimoto, Hiroshi Asanuma, Hiroyuki Sato, Tsunenori Arai, Shunichi Sato, Isao Sakata, Takeshi Takemura, Susumu Nakajima, Makoto Kikuchi

Proceedings Volume 4952, (2003) https://doi.org/10.1117/12.474150

KEYWORDS: Oxygen, Photodynamic therapy, Luminescence, Diffusion, Phototherapy, In vitro testing, Pulsed laser operation, Defense and security, Physics, Medicine

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Proceedings Article | 27 June 2002 Paper

Development for medical surgical system with function variability and flexible delivery using dual-wavelength infrared fiber laser

Kyota Naruse, Tsunenori Arai, Satoko Kawauchi, Tetsumi Sumiyoshi, Shoichi Kiyoshima, Miya Ishihara, Shunichi Sato, Makoto Kikuchi, Hitoshi Sekita, Minoru Obara

Proceedings Volume 4617, (2002) https://doi.org/10.1117/12.472515

KEYWORDS: Fiber lasers, Optical filters, Sapphire, Infrared radiation, Laser cutting, Infrared lasers, Laser dentistry, Tissues, Beam delivery, Laser tissue interaction

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Proceedings Article | 17 June 2002 Paper

Transdermal delivery of photosensitizer by laser-induced stress wave

Makoto Ogura, Shunichi Sato, Masahiko Kuroki, Hitoshi Wakisaka, Satoko Kawauchi, Miya Ishihara, Makoto Kikuchi, Masahiko Yoshioka, Hiroshi Ashida, Minoru Obara

Proceedings Volume 4609, (2002) https://doi.org/10.1117/12.432076

KEYWORDS: Skin, Opacity, Liquid crystals, Luminescence, Defense and security, Solids, Sodium, Plasma, Electronics, HVAC controls

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Proceedings Article | 10 June 2002 Paper

Photoacoustic signal measurement for burned skins in the spectral range of 500-650 nm: experiment with rat burn models

Mutsuo Yamazaki, Shunichi Sato, Daizo Saito, Masanori Fujita, Yoshiaki Okada, Makoto Kikuchi, Hiroshi Ashida, Minoru Obara

Proceedings Volume 4618, (2002) https://doi.org/10.1117/12.469862

KEYWORDS: Photoacoustic spectroscopy, Skin, Transducers, Blood, Tissues, Optical parametric oscillators, Acoustics, Quartz, Biomedical optics, Defense and security

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Proceedings Article | 26 March 2002 Paper

Hollow-waveguide-based laser-to-ultrasound transducer for drug delivery application

Shunichi Sato, Makoto Ogura, Minoru Obara, Yi-Wei Shi, Yuji Matsuura, Mitsunobu Miyagi, Hiroshi Ashida

Proceedings Volume 4616, (2002) https://doi.org/10.1117/12.463814

KEYWORDS: Tissues, Hollow waveguides, Transducers, Laser applications, Plasma, Waveguides, Acoustics, Ultrasonography, Rhodamine B, Laser tissue interaction

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Proceedings Article | 24 October 2001 Paper

Measurement of photoacoustic signals from skin: potential application to burn depth estimation

Shunichi Sato, Tomoaki Shimada, Tsunenori Arai, Makoto Kikuchi, Minoru Obara, Hiroshi Ashida

Proceedings Volume 4434, (2001) https://doi.org/10.1117/12.446677

KEYWORDS: Skin, Photoacoustic spectroscopy, Transducers, Injuries, Tissues, Signal detection, Absorption, Blood, Acoustics, Natural surfaces

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Proceedings Article | 9 July 2001 Paper

Nanosecond-time-response temperature measurements using radiation thermometry during 193-nm and 247-nm pulsed light irradiation: comparison of corneal surface temperature histories

Miya Ishihara, Tsunenori Arai, Shunichi Sato, Yuji Morimoto, Minoru Obara, Makoto Kikuchi

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434712

KEYWORDS: Temperature metrology, Absorption, Cornea, Laser ablation, Excimer lasers, Radiometry, Radiation thermometry, Light sources, Defense and security, Laser development

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Proceedings Article | 9 July 2001 Paper

Channeling in myocardium tissue through nanosecond pulsed laser photodisruption at visible and near-infrared wavelengths

Makoto Ogura, Shunichi Sato, Tsunenori Arai, Miya Ishihara, Satoko Kawauchi, Takemi Matsui, Akira Kurita, Makoto Kikuchi, Hitoshi Wakisaka, Hiroshi Ashida, Minoru Obara

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434714

KEYWORDS: Laser ablation, Laser optics, Laser tissue interaction, Pulsed laser operation, Tissue optics, Tissues, Plasma, Laser irradiation, Laser damage threshold, Q switched lasers

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Proceedings Article | 9 July 2001 Paper

Theoretical study of variable function (cutting/coagulating) laser surgical system using continuous-wave 3 um, 2u m cascade Ho3+:ZBLAN fiber laser

Kyota Naruse, Tsunenori Arai, Satoko Kawauchi, Tetsumi Sumiyoshi, Shoichi Kiyoshima, Miya Ishihara, Shunichi Sato, Makoto Kikuchi, Hitoshi Sekita, Minoru Obara

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434718

KEYWORDS: Fiber lasers, Quantum cascade lasers, Tissues, Laser cutting, Absorption, Laser tissue interaction, Laser dentistry, Continuous wave operation, Microscopes, Laser systems engineering

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Proceedings Article | 4 June 2001 Paper

Myocardium tissue ablation with hollow-waveguide-delivered near-infrared nanosecond laser pulses

Shunichi Sato, Tsunenori Arai, Yi-Wei Shi, Yuji Matsuura, Mitsunobu Miyagi, Hiroshi Ashida

Proceedings Volume 4253, (2001) https://doi.org/10.1117/12.427917

KEYWORDS: Laser ablation, Waveguides, Laser tissue interaction, Pulsed laser operation, Hollow waveguides, Laser energy, Beam delivery, Laser applications, Tissue optics, Collimation

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Proceedings Article | 9 April 2001 Paper

Influence of light intensity and repetition rate of nanosecond laser pulses on photodynamic therapy with PAD-S31 in mouse renal carcinoma cell line in vitro: study for oxygen consumption and photo..

Satoko Kawauchi, Tsunenori Arai, Kenji Seguchi, Hiroshi Asanuma, Shunichi Sato, Makoto Kikuchi, Takeshi Takemura, Isao Sakata, Susumu Nakajima

Proceedings Volume 4248, (2001) https://doi.org/10.1117/12.424445

KEYWORDS: Photodynamic therapy, Oxygen, Luminescence, In vitro testing, Diffusion, Laser therapeutics, Defense and security, Sodium, Finite element methods, Fluorescence spectroscopy

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Proceedings Article | 25 January 2001 Paper

Comprehensive computer simulation on fundamental-band and first-overtone carbon monoxide lasers

Katsuhisa Takada, Yoshitaka Maekawa, Mitsuhiro Iyoda, Manabu Taniwaki, Kouki Shimizu, Shunichi Sato

Proceedings Volume 4184, (2001) https://doi.org/10.1117/12.414062

KEYWORDS: Gas lasers, Computer simulations, Continuous wave operation, Mirrors, Carbon monoxide, Computer programming, High power lasers, Medical research, Laser applications

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Proceedings Article | 16 November 2000 Paper

Plasma-mediated tissue ablation with nanosecond laser pulses in the spectral region from ultraviolet to near infrared: in-vitro study with porcine myocardium tissue

Shunichi Sato, Makoto Ogura, Tomoaki Shimada, Miya Ishihara, Tsunenori Arai, Takemi Matsui, Akira Kurita, Minoru Obara, Makoto Kikuchi, Hitoshi Wakisaka, Hiroshi Ashida

Proceedings Volume 4161, (2000) https://doi.org/10.1117/12.409316

KEYWORDS: Laser ablation, Laser tissue interaction, Laser optics, Laser irradiation, Plasma, Tissue optics, Pulsed laser operation, Nd:YAG lasers, Optical microscopes, In vitro testing

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Proceedings Article | 13 June 2000 Paper

Laser-tissue interaction of a continuous-wave 2-um, 3-um cascade oscillation fiber laser: sharp incision with controlled coagulation layer thickness

Tsunenori Arai, Tetsumi Sumiyoshi, Kyota Naruse, Miya Ishihara, Shunichi Sato, Makoto Kikuchi, Tadashi Kasamatsu, Hitoshi Sekita, Minoru Obara

Proceedings Volume 3914, (2000) https://doi.org/10.1117/12.388052

KEYWORDS: Fiber lasers, Laser tissue interaction, Laser cutting, Laser systems engineering, Continuous wave operation, Laser development, Photography, Tissues, Laser therapeutics, Liver

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Proceedings Article | 13 June 2000 Paper

65MHz bandwidth measurement of thermal emission induced by ArF excimer laser ablation of cornea

Miya Ishihara, Shunichi Sato, Tsunenori Arai, Minoru Obara, Makoto Kikuchi

Proceedings Volume 3914, (2000) https://doi.org/10.1117/12.388031

KEYWORDS: Cornea, Excimer lasers, Temperature metrology, Laser ablation, Mercury cadmium telluride, Sensors, Photovoltaic detectors, Photovoltaics, Tissues, Signal detection

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Proceedings Article | 13 June 2000 Paper

Myocardium tissue ablation with nanosecond ultraviolet pulses: in-vitro study with porcine myocardium tissues

Tomoaki Shimada, Shunichi Sato, Miya Ishihara, Tsunenori Arai, Takemi Matsui, Akira Kurita, Makoto Kikuchi, Hitoshi Wakisaka, Hiroshi Ashida, Minoru Obara

Proceedings Volume 3914, (2000) https://doi.org/10.1117/12.388029

KEYWORDS: Laser ablation, Tissues, Tissue optics, Optical parametric oscillators, Ultraviolet radiation, Laser tissue interaction, Signal attenuation, Nd:YAG lasers, In vitro testing, Absorption

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Proceedings Article | 3 May 2000 Paper

Vacuum-cored hollow waveguide for high-energy high-intensity laser transmission and its application to biological tissue ablation

Shunichi Sato, Tsunenori Arai, Yi-Wei Shi, Yuji Matsuura, Mitsunobu Miyagi, Hiroshi Ashida

Proceedings Volume 3911, (2000) https://doi.org/10.1117/12.384917

KEYWORDS: Waveguides, Laser ablation, Hollow waveguides, Laser energy, Laser tissue interaction, Coating, Nd:YAG lasers, Q switched lasers, Laser damage threshold, Laser induced damage

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Proceedings Article | 3 April 2000 Paper

High-power room-temperature-operated CO laser

Kouki Shimizu, Manabu Taniwaki, Shunichi Sato, Mikio Kumagai, Yoich Takashima, Yasuhiro Naito, Hiroshi Nagano, Toru Hasuike

Proceedings Volume 3889, (2000) https://doi.org/10.1117/12.380915

KEYWORDS: Gas lasers, Krypton, Xenon, Carbon monoxide, Carbon dioxide lasers, High power lasers, Carbon dioxide, Electrodes, Gases, Molecules

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Proceedings Article | 1 February 2000 Paper

Characteristics and mechanism of myocardium tissue laser ablation: in-vitro study for transmyocardial laser revascularization

Shunichi Sato, Tomoaki Shimada, Makoto Ogura, Miya Ishihara, Tsunenori Arai, Takemi Matsui, Akira Kurita, Minoru Obara, Makoto Kikuchi, Hitoshi Wakisaka, Hiroshi Ashida

Proceedings Volume 3885, (2000) https://doi.org/10.1117/12.376956

KEYWORDS: Laser ablation, Laser tissue interaction, Plasma, Tissues, Optical parametric oscillators, Nd:YAG lasers, In vitro testing, Q switched lasers, Ultraviolet radiation, Absorption

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Proceedings Article | 14 January 2000 Paper

Evaluation of secondary contamination in laser cutting of surface-contaminated metals

Kunimitsu Takahashi, Shunichi Sato, Tadashi Fukushima, Akira Sano, Yasuhisa Ikeda, Yoich Takashima

Proceedings Volume 3887, (2000) https://doi.org/10.1117/12.375209

KEYWORDS: Laser cutting, Oxygen, Molybdenum, Metals, Optical simulations, Contamination, Nitrogen, Chemical analysis, X-rays, Oxidation

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Proceedings Article | 14 June 1999 Paper

Temperature monitoring by infrared radiation measurements during ArF excimer laser ablation with cornea

Miya Ishihara, Tsunenori Arai, Shunichi Sato, Hironori Nakano, Minoru Obara, Makoto Kikuchi

Proceedings Volume 3601, (1999) https://doi.org/10.1117/12.350017

KEYWORDS: Laser ablation, Cornea, Temperature metrology, Excimer lasers, Sensors, Infrared radiation, Time metrology, Pulsed laser operation, Thermography, Laser tissue interaction

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Proceedings Article | 21 April 1999 Paper

Hollow-waveguide-based transmission of a Q-switched Nd:YAG laser beam for biological tissue ablation

Shunichi Sato, Hiroshi Ashida, Yi-Wei Shi, Yuji Matsuura, Mitsunobu Miyagi

Proceedings Volume 3596, (1999) https://doi.org/10.1117/12.346726

KEYWORDS: Waveguides, Nd:YAG lasers, Hollow waveguides, Laser energy, Q switched lasers, Silver, Laser tissue interaction, Laser ablation, Energy efficiency, Laser applications

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Proceedings Article | 15 January 1999 Paper

New cyclic olefin polymer-coated silver hollow glass waveguides for the near-infrared to mid-infrared

Yi-Wei Shi, Konosuke Hanamoto, You Wang, Yukio Abe, Yuji Matsuura, Shunichi Sato, Mitsunobu Miyagi

Proceedings Volume 3570, (1999) https://doi.org/10.1117/12.336914

KEYWORDS: Waveguides, Glasses, Gas lasers, Polymers, Silver, Er:YAG lasers, Polymer multimode waveguides, Nd:YAG lasers, Carbon monoxide, Carbon dioxide lasers

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Proceedings Article | 22 December 1998 Paper

Distributed computing for CO laser simulation

Manabu Taniwaki, Shunichi Sato, Yoshitaka Maekawa, Mitsuhiro Iyoda

Proceedings Volume 3574, (1998) https://doi.org/10.1117/12.334485

KEYWORDS: Java, Gas lasers, Computer simulations, Optical simulations, Visualization, Distributed computing, Internet, Human-machine interfaces, Laser development, Medical research

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Proceedings Article | 8 July 1998 Paper

Thin film synthesis with ultrafast lasers

Peter Pronko, Paul VanRompay, Shunichi Sato

Proceedings Volume 3269, (1998) https://doi.org/10.1117/12.312331

KEYWORDS: Plasmas, Ions, Laser ablation, Ultrafast lasers, Absorption, Boron, Pulsed laser operation, Thin films, Silicon, Fusion energy

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Proceedings Article | 5 June 1998 Paper

Fabrication of cyclic olefin polymer (COP)-coated silver hollow glass waveguides for the infrared

Yi-Wei Shi, You Wang, Yukio Abe, Yuji Matsuura, Mitsunobu Miyagi, Hiroshi Uyama, Manabu Taniwaki, Shunichi Sato

Proceedings Volume 3262, (1998) https://doi.org/10.1117/12.309461

KEYWORDS: Waveguides, Silver, Glasses, Er:YAG lasers, Hollow waveguides, Gas lasers, Infrared radiation, Polymers, Carbon dioxide lasers, Coating

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Proceedings Article | 12 May 1998 Paper

High-power 5-um-band CO laser and its new hollow waveguides for industrial applications

Shunichi Sato, Kouki Shimizu, Yi-Wei Shi, Mitsunobu Miyagi

Proceedings Volume 3268, (1998) https://doi.org/10.1117/12.308088

KEYWORDS: Gas lasers, Carbon dioxide lasers, High power lasers, Carbon monoxide, Xenon, Electrodes, Surgery, Beam delivery, Molecules, Hollow waveguides

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Proceedings Article | 20 March 1997 Paper

Application of slip-band visualization technique to tensile analysis of laser-welded aluminum alloy

- Muchiar, Sanichiro Yoshida, Rini Widiastuti, A. Kusnowo, Kunimitsu Takahashi, Shunichi Sato

Proceedings Volume 2921, (1997) https://doi.org/10.1117/12.269819

KEYWORDS: Interferometers, Aluminum, Speckle, Visualization, Visual analytics, Image processing, Analytical research, Interferometry, Solid state electronics, Statistical analysis

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Proceedings Article | 31 March 1995 Paper

Fast Fourier transform (FFT) analysis of CO laser beam mode based on personal computer (PC) and workstation

Mitsuhiro Iyoda, Hidetoshi Okaya, Mamoru Akiyama, Manabu Taniwaki, Shunichi Sato

Proceedings Volume 2502, (1995) https://doi.org/10.1117/12.204909

KEYWORDS: Gas lasers, Computer simulations, Fourier transforms, Beam analyzers, Beam propagation method, Refraction, Optical filters, Electronic filtering, Computing systems, Laser development

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Proceedings Article | 25 May 1994 Paper

High-performance fast-axial-flow radio-frequency discharge-excited CO laser

Kouki Shimizu, Shunichi Sato, Kojiro Shimamoto, Yasunobu Takahashi

Proceedings Volume 2118, (1994) https://doi.org/10.1117/12.176651

KEYWORDS: Electrodes, Gas lasers, Quartz, Carbon dioxide lasers, Microwave radiation, Photography, Near field, High power lasers, Thermal effects, Analytical research

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Proceedings Article | 4 May 1993 Paper

PC-based beam mode analysis of CO laser

Mitsuhiro Iyoda, Yuki Yamaguchi, Hidetoshi Okaya, Mamoru Akiyama, Manabu Taniwaki, Shunichi Sato

Proceedings Volume 1810, (1993) https://doi.org/10.1117/12.144569

KEYWORDS: Gas lasers, Beam analyzers, Computer programming, Laser development, Near field, Computer simulations, Mirrors, Chemical lasers, Output couplers, Optical simulations

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Proceedings Article | 1 May 1991 Paper

One-dimensional and two-dimensional computer models of industrial CO laser

Mitsuhiro Iyoda, Tomoya Murota, Mamoru Akiyama, Shunichi Sato

Proceedings Volume 1415, (1991) https://doi.org/10.1117/12.43699

KEYWORDS: Gas lasers, Optical simulations, Computer simulations, Carbon monoxide, Systems modeling, Modeling and simulation, Laser systems engineering, Laser development, Energy transfer, Molecules

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